PubMed

Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival.

Kovacheva VP, Davison JM, Mellott TJ, Rogers AE, Yang S, O'Brien MJ, Blusztajn JK.

FASEB J. 2009 Apr;23(4):1054-63. Epub 2008 Dec 1.PMID: 19047067 [PubMed - indexed for MEDLINE]Related articles

Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain.

Davison JM, Mellott TJ, Kovacheva VP, Blusztajn JK.

J Biol Chem. 2009 Jan 23;284(4):1982-9. Epub 2008 Nov 10.PMID: 19001366 [PubMed - indexed for MEDLINE]Related articles

Developmental periods of choline sensitivity provide an ontogenetic mechanism for regulating memory capacity and age-related dementia.

Meck WH, Williams CL, Cermak JM, Blusztajn JK.

Front Integr Neurosci. 2007;1:7. Epub 2008 May 3.PMID: 18958235 [PubMed - in process]Related articlesFree article

Differential modulation of nerve growth factor receptor (p75) and cholinergic gene expression in purified p75-expressing and non-expressing basal forebrain neurons by BMP9.

Schnitzler AC, Lopez-Coviella I, Blusztajn JK.

Brain Res. 2008 Dec 30;1246:19-28. Epub 2008 Oct 14.PMID: 18952073 [PubMed - indexed for MEDLINE]Related articles

Nerve growth factor regulates the expression of the cholinergic locus and the high-affinity choline transporter via the Akt/PKB signaling pathway.

Madziar B, Shah S, Brock M, Burke R, Lopez-Coviella I, Nickel AC, Cakal EB, Blusztajn JK, Berse B.

J Neurochem. 2008 Dec;107(5):1284-93. Epub 2008 Sep 13.PMID: 18793330 [PubMed - indexed for MEDLINE]Related articles

Prenatal choline supplementation in rats increases the expression of IGF2 and its receptor IGF2R and enhances IGF2-induced acetylcholine release in hippocampus and frontal cortex.

Napoli I, Blusztajn JK, Mellott TJ.

Brain Res. 2008 Oct 27;1237:124-35. Epub 2008 Aug 28.PMID: 18786520 [PubMed - indexed for MEDLINE]Related articles

Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats.

Glenn MJ, Kirby ED, Gibson EM, Wong-Goodrich SJ, Mellott TJ, Blusztajn JK, Williams CL.

Brain Res. 2008 Oct 27;1237:110-23. Epub 2008 Aug 28.PMID: 18786518 [PubMed - indexed for MEDLINE]Related articlesFree article

Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero.

Wong-Goodrich SJ, Glenn MJ, Mellott TJ, Blusztajn JK, Meck WH, Williams CL.

Brain Res. 2008 Oct 27;1237:153-66. Epub 2008 Sep 4.PMID: 18778697 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus.

Wong-Goodrich SJ, Mellott TJ, Glenn MJ, Blusztajn JK, Williams CL.

Neurobiol Dis. 2008 May;30(2):255-69. Epub 2008 Feb 16.PMID: 18353663 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of mTOR-dependent S6 phosphorylation by muscarinic acetylcholine receptor subtypes.

Slack BE, Blusztajn JK.

J Cell Biochem. 2008 Aug 1;104(5):1818-31.PMID: 18348264 [PubMed - indexed for MEDLINE]Related articles

Purification and culture of nerve growth factor receptor (p75)-expressing basal forebrain cholinergic neurons.

Schnitzler AC, Lopez-Coviella I, Blusztajn JK.

Nat Protoc. 2008;3(1):34-40.PMID: 18193019 [PubMed - indexed for MEDLINE]Related articles

Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of Dnmt1 expression.

Kovacheva VP, Mellott TJ, Davison JM, Wagner N, Lopez-Coviella I, Schnitzler AC, Blusztajn JK.

J Biol Chem. 2007 Oct 26;282(43):31777-88. Epub 2007 Aug 27.PMID: 17724018 [PubMed - indexed for MEDLINE]Related articlesFree article

A cyclic peptide that binds p75(NTR) protects neurones from beta amyloid (1-40)-induced cell death.

Yaar M, Zhai S, Panova I, Fine RE, Eisenhauer PB, Blusztajn JK, Lopez-Coviella I, Gilchrest BA.

Neuropathol Appl Neurobiol. 2007 Oct;33(5):533-43. Epub 2007 Jun 27.PMID: 17596181 [PubMed - indexed for MEDLINE]Related articles

Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats.

Glenn MJ, Gibson EM, Kirby ED, Mellott TJ, Blusztajn JK, Williams CL.

Eur J Neurosci. 2007 Apr;25(8):2473-82.PMID: 17445242 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats.

Mellott TJ, Kowall NW, Lopez-Coviella I, Blusztajn JK.

Brain Res. 2007 Jun 2;1151:1-11. Epub 2007 Mar 12.PMID: 17399691 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of the high affinity choline transporter and the cholinergic locus by cAMP signaling pathways.

Brock M, Nickel AC, Madziar B, Blusztajn JK, Berse B.

Brain Res. 2007 May 11;1145:1-10. Epub 2007 Feb 2.PMID: 17320829 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal choline availability modulates hippocampal and cerebral cortical gene expression.

Mellott TJ, Follettie MT, Diesl V, Hill AA, Lopez-Coviella I, Blusztajn JK.

FASEB J. 2007 May;21(7):1311-23. Epub 2007 Jan 30.PMID: 17264169 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain.

Lopez-Coviella I, Mellott TM, Kovacheva VP, Berse B, Slack BE, Zemelko V, Schnitzler A, Blusztajn JK.

Brain Res. 2006 May 9;1088(1):49-56. Epub 2006 Apr 13.PMID: 16626664 [PubMed - indexed for MEDLINE]Related articles

Collagen type I selectively activates ectodomain shedding of the discoidin domain receptor 1: involvement of Src tyrosine kinase.

Slack BE, Siniaia MS, Blusztajn JK.

J Cell Biochem. 2006 Jun 1;98(3):672-84.PMID: 16440311 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of high affinity choline transporter during mouse development in vivo and its upregulation by NGF and BMP-4 in vitro.

Berse B, Szczecinska W, Lopez-Coviella I, Madziar B, Zemelko V, Kaminski R, Kozar K, Lips KS, Pfeil U, Blusztajn JK.

Brain Res Dev Brain Res. 2005 Jun 30;157(2):132-40.PMID: 15885806 [PubMed - indexed for MEDLINE]Related articles

Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons.

Lopez-Coviella I, Follettie MT, Mellott TJ, Kovacheva VP, Slack BE, Diesl V, Berse B, Thies RS, Blusztajn JK.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6984-9. Epub 2005 May 3.PMID: 15870197 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways.

Kaczmarek E, Erb L, Koziak K, Jarzyna R, Wink MR, Guckelberger O, Blusztajn JK, Trinkaus-Randall V, Weisman GA, Robson SC.

Thromb Haemost. 2005 Apr;93(4):735-42.PMID: 15841322 [PubMed - indexed for MEDLINE]Related articles

Nutrients as trophic factors in neurons and the central nervous system: role of retinoic acid.

Malik MA, Blusztajn JK, Greenwood CE.

J Nutr Biochem. 2000 Jan;11(1):2-13.PMID: 15539337 [PubMed]Related articles

Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency.

Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK.

J Neurosci. 2004 Jun 16;24(24):5459-66.PMID: 15201317 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation.

Mellott TJ, Williams CL, Meck WH, Blusztajn JK.

FASEB J. 2004 Mar;18(3):545-7. Epub 2004 Jan 8.PMID: 14715695 [PubMed - indexed for MEDLINE]Related articlesFree article

Toxicity of glucosylsphingosine (glucopsychosine) to cultured neuronal cells: a model system for assessing neuronal damage in Gaucher disease type 2 and 3.

Schueler UH, Kolter T, Kaneski CR, Blusztajn JK, Herkenham M, Sandhoff K, Brady RO.

Neurobiol Dis. 2003 Dec;14(3):595-601.PMID: 14678774 [PubMed - indexed for MEDLINE]Related articles

Synthesis of acetylcholine by lung cancer.

Song P, Sekhon HS, Proskocil B, Blusztajn JK, Mark GP, Spindel ER.

Life Sci. 2003 Mar 28;72(18-19):2159-68.PMID: 12628474 [PubMed - indexed for MEDLINE]Related articles

Acetylcholine is synthesized by and acts as an autocrine growth factor for small cell lung carcinoma.

Song P, Sekhon HS, Jia Y, Keller JA, Blusztajn JK, Mark GP, Spindel ER.

Cancer Res. 2003 Jan 1;63(1):214-21.PMID: 12517800 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression.

Mellott T, Lopez-Coviella I, Blusztajn JK, Berse B.

Eur J Biochem. 2002 Feb;269(3):850-8.PMID: 11846786 [PubMed - indexed for MEDLINE]Related articlesFree article

Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus.

Holmes GL, Yang Y, Liu Z, Cermak JM, Sarkisian MR, Stafstrom CE, Neill JC, Blusztajn JK.

Epilepsy Res. 2002 Jan;48(1-2):3-13.PMID: 11823105 [PubMed - indexed for MEDLINE]Related articles

[Bone morphogenetic proteins and cholinergic neurons in the central nervous system]

López-Coviella I, Blusztajn JK.

Rev Neurol. 2001 Dec 1-15;33(11):1054-60. Review. Spanish. PMID: 11785034 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal choline supplementation protects against postnatal neurotoxicity.

Guo-Ross SX, Clark S, Montoya DA, Jones KH, Obernier J, Shetty AK, White AM, Blusztajn JK, Wilson WA, Swartzwelder HS.

J Neurosci. 2002 Jan 1;22(1):RC195.PMID: 11756524 [PubMed - indexed for MEDLINE]Related articlesFree article

Upregulation of acetylcholine synthesis by bone morphogenetic protein 9 in a murine septal cell line.

López-Coviella I, Berse B, Thies RS, Blusztajn JK.

J Physiol Paris. 2002 Jan-Mar;96(1-2):53-9.PMID: 11755783 [PubMed - indexed for MEDLINE]Related articles

Generation of choline for acetylcholine synthesis by phospholipase D isoforms.

Zhao D, Frohman MA, Blusztajn JK.

BMC Neurosci. 2001;2:16. Epub 2001 Oct 19.PMID: 11734063 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex steroids modulate luteinizing hormone-releasing hormone secretion in a cholinergic cell line from the basal forebrain.

Martínez-Morales JR, López-Coviella I, Hernández-Jiménez JG, Reyes R, Bello AR, Hernández G, Blusztajn JK, Alonso R.

Neuroscience. 2001;103(4):1025-31.PMID: 11301209 [PubMed - indexed for MEDLINE]Related articles

Protective effects of prenatal choline supplementation on seizure-induced memory impairment.

Yang Y, Liu Z, Cermak JM, Tandon P, Sarkisian MR, Stafstrom CE, Neill JC, Blusztajn JK, Holmes GL.

J Neurosci. 2000 Nov 15;20(22):RC109.PMID: 11069978 [PubMed - indexed for MEDLINE]Related articlesFree article

Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease.

Farber SA, Slack BE, Blusztajn JK.

FASEB J. 2000 Nov;14(14):2198-206.PMID: 11053240 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal choline exposure alters hippocampal responsiveness to cholinergic stimulation in adulthood.

Montoya DA, White AM, Williams CL, Blusztajn JK, Meck WH, Swartzwelder HS.

Brain Res Dev Brain Res. 2000 Sep 30;123(1):25-32.PMID: 11020547 [PubMed - indexed for MEDLINE]Related articles

Cholinergic differentiation triggered by blocking cell proliferation and treatment with all-trans-retinoic acid.

Malik MA, Greenwood CE, Blusztajn JK, Berse B.

Brain Res. 2000 Aug 25;874(2):178-85.PMID: 10960602 [PubMed - indexed for MEDLINE]Related articles

Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9.

López-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK.

Science. 2000 Jul 14;289(5477):313-6.PMID: 10894782 [PubMed - indexed for MEDLINE]Related articlesFree article

The cholinergic neuronal phenotype in Alzheimer's disease.

Blusztajn JK, Berse B.

Metab Brain Dis. 2000 Mar;15(1):45-64. Review.PMID: 10885540 [PubMed - indexed for MEDLINE]Related articles

Changes in phospholipase D isoform activity and expression in multidrug-resistant human cancer cells.

Fiucci G, Czarny M, Lavie Y, Zhao D, Berse B, Blusztajn JK, Liscovitch M.

Int J Cancer. 2000 Mar 15;85(6):882-8.PMID: 10709112 [PubMed - indexed for MEDLINE]Related articles

Palmitoylation targets CD39/endothelial ATP diphosphohydrolase to caveolae.

Koziak K, Kaczmarek E, Kittel A, Sévigny J, Blusztajn JK, Schulte Am Esch J 2nd, Imai M, Guckelberger O, Goepfert C, Qawi I, Robson SC.

J Biol Chem. 2000 Jan 21;275(3):2057-62.PMID: 10636909 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein serum amyloid A down-regulates smooth-muscle cell lipid biosynthesis.

Schreiber BM, Veverbrants M, Fine RE, Blusztajn JK, Salmona M, Patel A, Sipe JD.

Biochem J. 1999 Nov 15;344 Pt 1:7-13.PMID: 10548527 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor.

Berse B, Lopez-Coviella I, Blusztajn JK.

Biochem J. 1999 Sep 1;342 ( Pt 2):301-8.PMID: 10455015 [PubMed - indexed for MEDLINE]Related articlesFree article

Prenatal availability of choline alters the development of acetylcholinesterase in the rat hippocampus.

Cermak JM, Blusztajn JK, Meck WH, Williams CL, Fitzgerald CM, Rosene DL, Loy R.

Dev Neurosci. 1999;21(2):94-104.PMID: 10449981 [PubMed - indexed for MEDLINE]Related articles

Acetylcholine and acetyl-CoA metabolism in differentiating SN56 septal cell line.

Szutowicz A, Jankowska A, Blusztajn JK, Tomaszewicz M.

J Neurosci Res. 1999 Jul 1;57(1):131-6.PMID: 10397643 [PubMed - indexed for MEDLINE]Related articles

Imprinting of hippocampal metabolism of choline by its availability during gestation: implications for cholinergic neurotransmission.

Blusztajn JK, Cermak JM, Holler T, Jackson DA.

J Physiol Paris. 1998 Jun-Aug;92(3-4):199-203.PMID: 9789808 [PubMed - indexed for MEDLINE]Related articles

Developmental changes in phospholipase D activity and mRNA levels in rat brain.

Zhao D, Berse B, Holler T, Cermak JM, Blusztajn JK.

Brain Res Dev Brain Res. 1998 Aug 8;109(2):121-7.PMID: 9729325 [PubMed - indexed for MEDLINE]Related articles

Choline, a vital amine.

Blusztajn JK.

Science. 1998 Aug 7;281(5378):794-5. No abstract available. PMID: 9714685 [PubMed - indexed for MEDLINE]Related articles

Sexually dimorphic activation of liver and brain phosphatidylethanolamine N-methyltransferase by dietary choline deficiency.

Johnson PI, Blusztajn JK.

Neurochem Res. 1998 May;23(5):583-7.PMID: 9566595 [PubMed - indexed for MEDLINE]Related articles

Prenatal availability of choline modifies development of the hippocampal cholinergic system.

Cermak JM, Holler T, Jackson DA, Blusztajn JK.

FASEB J. 1998 Mar;12(3):349-57.PMID: 9506479 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the acetylcholine-reducing effect of the amyloid-beta peptide in mouse SN56 cells.

Pedersen WA, Blusztajn JK.

Neurosci Lett. 1997 Dec 19;239(2-3):77-80.PMID: 9469660 [PubMed - indexed for MEDLINE]Related articles

A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization.

Li H, Leeman SE, Slack BE, Hauser G, Saltsman WS, Krause JE, Blusztajn JK, Boyd ND.

Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9475-80.PMID: 9256507 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of cholinergic locus expression by glucocorticoids and retinoic acid is cell-type specific.

Berse B, Blusztajn JK.

FEBS Lett. 1997 Jun 30;410(2-3):175-9.PMID: 9237624 [PubMed - indexed for MEDLINE]Related articles

Phospholipid biosynthetic enzymes in human brain.

Ross BM, Moszczynska A, Blusztajn JK, Sherwin A, Lozano A, Kish SJ.

Lipids. 1997 Apr;32(4):351-8.PMID: 9113621 [PubMed - indexed for MEDLINE]Related articles

Activities of enzymes of acetyl-CoA and acetylcholine metabolism in SN56 hybrid cholinergic cell line differentiated by dibutyryl cyclic AMP and all-trans retinoic acid.

Jankowska A, Blusztajn JK, Szutowicz A.

Folia Neuropathol. 1997;35(4):247-9.PMID: 9833404 [PubMed - indexed for MEDLINE]Related articles

Cell culture models of interspecies selectivity to organophosphorous insecticides.

Veronesi B, Ehrich M, Blusztajn JK, Oortgiesen M, Durham H.

Neurotoxicology. 1997;18(1):283-97. Review.PMID: 9216006 [PubMed - indexed for MEDLINE]Related articles

Dietary choline supplementation in pregnant rats increases hippocampal phospholipase D activity of the offspring.

Holler T, Cermak JM, Blusztajn JK.

FASEB J. 1996 Dec;10(14):1653-9.PMID: 9002559 [PubMed - indexed for MEDLINE]Related articlesFree article

Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain.

Pedersen WA, Kloczewiak MA, Blusztajn JK.

Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):8068-71.PMID: 8755604 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences in the developmental expression of the vesicular acetylcholine transporter and choline acetyltransferase in the rat brain.

Holler T, Berse B, Cermak JM, Diebler MF, Blusztajn JK.

Neurosci Lett. 1996 Jul 12;212(2):107-10.PMID: 8832650 [PubMed - indexed for MEDLINE]Related articles

Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.

Lemere CA, Blusztajn JK, Yamaguchi H, Wisniewski T, Saido TC, Selkoe DJ.

Neurobiol Dis. 1996 Feb;3(1):16-32.PMID: 9173910 [PubMed - indexed for MEDLINE]Related articles

Retinoic acid specifically increases nuclear PKC alpha and stimulates AP-1 transcriptional activity in B16 mouse melanoma cells.

Gruber JR, Desai S, Blusztajn JK, Niles RM.

Exp Cell Res. 1995 Dec;221(2):377-84.PMID: 7493637 [PubMed - indexed for MEDLINE]Related articles

Coordinated up-regulation of choline acetyltransferase and vesicular acetylcholine transporter gene expression by the retinoic acid receptor alpha, cAMP, and leukemia inhibitory factor/ciliary neurotrophic factor signaling pathways in a murine septal cell line.

Berse B, Blusztajn JK.

J Biol Chem. 1995 Sep 22;270(38):22101-4.PMID: 7673184 [PubMed - indexed for MEDLINE]Related articlesFree article

Radioactive choline metabolism in guinea pig gallbladder. Is there measurable acetylcholine release?

Brotschi EA, Hilbinger CL, Kahl EA, Vaules WA, Midis NA, Blusztajn JK, Zeisel SH.

Dig Dis Sci. 1995 Sep;40(9):1982-9.PMID: 7555453 [PubMed - indexed for MEDLINE]Related articles

All-trans- and 9-cis-retinoic acid enhance the cholinergic properties of a murine septal cell line: evidence that the effects are mediated by activation of retinoic acid receptor-alpha.

Pedersen WA, Berse B, Schüler U, Wainer BH, Blusztajn JK.

J Neurochem. 1995 Jul;65(1):50-8.PMID: 7790895 [PubMed - indexed for MEDLINE]Related articles

Use of differentiated cholinergic and second messenger endpoints to evaluate cholinesterase inhibitors.

Blusztajn JK, Davis RO.

Clin Exp Pharmacol Physiol. 1995 May;22(5):368-9.PMID: 7554433 [PubMed - indexed for MEDLINE]Related articles

Modulation by sphingolipids of calcium signals evoked by epidermal growth factor.

Hudson PL, Pedersen WA, Saltsman WS, Liscovitch M, MacLaughlin DT, Donahoe PK, Blusztajn JK.

J Biol Chem. 1994 Aug 26;269(34):21885-90.PMID: 8063833 [PubMed - indexed for MEDLINE]Related articlesFree article

Formation of endogenous free sphingoid bases in cells induced by changing medium conditions.

Lavie Y, Blusztajn JK, Liscovitch M.

Biochim Biophys Acta. 1994 Feb 17;1220(3):323-8.PMID: 8305506 [PubMed - indexed for MEDLINE]Related articles

Choline and human nutrition.

Zeisel SH, Blusztajn JK.

Annu Rev Nutr. 1994;14:269-96. Review.PMID: 7946521 [PubMed - indexed for MEDLINE]Related articles

Alzheimer's disease: prevention, models, and diagnostic tools.

Blusztajn JK.

Neurobiol Aging. 1994;15 Suppl 2:S37-9. Review. No abstract available. PMID: 7700457 [PubMed - indexed for MEDLINE]Related articles

Phospholipase D-catalyzed hydrolysis of phosphatidylcholine provides the choline precursor for acetylcholine synthesis in a human neuronal cell line.

Lee HC, Fellenz-Maloney MP, Liscovitch M, Blusztajn JK.

Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10086-90.PMID: 8234260 [PubMed - indexed for MEDLINE]Related articlesFree article

Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy.

Nitsch RM, Blusztajn JK, Doyle FM, Robitaille Y, Wurtman RJ, Growdon JH, Kish SJ.

Neurosci Lett. 1993 Oct 29;161(2):191-4.PMID: 8272265 [PubMed - indexed for MEDLINE]Related articles

Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline-deficient rats.

da Costa KA, Cochary EF, Blusztajn JK, Garner SC, Zeisel SH.

J Biol Chem. 1993 Jan 25;268(3):2100-5.PMID: 8420980 [PubMed - indexed for MEDLINE]Related articlesFree article

Measurement of the formation of betaine aldehyde and betaine in rat liver mitochondria by a high pressure liquid chromatography-radioenzymatic assay.

Zhang J, Blusztajn JK, Zeisel SH.

Biochim Biophys Acta. 1992 Oct 27;1117(3):333-9.PMID: 1420283 [PubMed - indexed for MEDLINE]Related articles

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons.

Cashman NR, Durham HD, Blusztajn JK, Oda K, Tabira T, Shaw IT, Dahrouge S, Antel JP.

Dev Dyn. 1992 Jul;194(3):209-21.PMID: 1467557 [PubMed - indexed for MEDLINE]Related articlesFree article

Acetylcholine synthesis and release is enhanced by dibutyryl cyclic AMP in a neuronal cell line derived from mouse septum.

Blusztajn JK, Venturini A, Jackson DA, Lee HJ, Wainer BH.

J Neurosci. 1992 Mar;12(3):793-9.PMID: 1312135 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a membrane defect in Alzheimer disease brain.

Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, Wurtman RJ.

Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1671-5.PMID: 1311847 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations of phospholipid metabolites in postmortem brain from patients with Alzheimer's disease.

Nitsch R, Pittas A, Blusztajn JK, Slack BE, Growdon JH, Wurtman RJ.

Ann N Y Acad Sci. 1991;640:110-3.PMID: 1663712 [PubMed - indexed for MEDLINE]Related articles

Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients.

Blusztajn JK, Lopez Gonzalez-Coviella I, Logue M, Growdon JH, Wurtman RJ.

Brain Res. 1990 Dec 17;536(1-2):240-4.PMID: 2150771 [PubMed - indexed for MEDLINE]Related articles

Choline metabolism in cholinergic neurons: implications for the pathogenesis of neurodegenerative diseases.

Wurtman RJ, Blusztajn JK, Ulus IH, Coviella IL, Buyukuysal RL, Growdon JH, Slack BE.

Adv Neurol. 1990;51:117-25. Review. No abstract available. PMID: 2403709 [PubMed - indexed for MEDLINE]Related articles

Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]choline into phosphatidylcholine.

Slack BE, Liscovitch M, Blusztajn JK, Wurtman RJ.

J Neurochem. 1989 Aug;53(2):472-81.PMID: 2746233 [PubMed - indexed for MEDLINE]Related articles

Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum.

Ulus IH, Wurtman RJ, Mauron C, Blusztajn JK.

Brain Res. 1989 Apr 10;484(1-2):217-27.PMID: 2713682 [PubMed - indexed for MEDLINE]Related articles

1,2-sn-diacylglycerol accumulates in choline-deficient liver. A possible mechanism of hepatic carcinogenesis via alteration in protein kinase C activity?

Blusztajn JK, Zeisel SH.

FEBS Lett. 1989 Jan 30;243(2):267-70.PMID: 2917651 [PubMed - indexed for MEDLINE]Related articles

Acetylcholine synthesis and secretion by LA-N-2 human neuroblastoma cells.

Richardson UI, Liscovitch M, Blusztajn JK.

Brain Res. 1989 Jan 9;476(2):323-31.PMID: 2702472 [PubMed - indexed for MEDLINE]Related articles

Effects of running the Boston marathon on plasma concentrations of large neutral amino acids.

Conlay LA, Wurtman RJ, Lopez G-Coviella I, Blusztajn JK, Vacanti CA, Logue M, During M, Caballero B, Maher TJ, Evoniuk G.

J Neural Transm. 1989;76(1):65-71.PMID: 2708978 [PubMed - indexed for MEDLINE]Related articles

Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine.

Yang EK, Blusztajn JK, Pomfret EA, Zeisel SH.

Biochem J. 1988 Dec 15;256(3):821-8.PMID: 3223955 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells.

Liscovitch M, Slack B, Blusztajn JK, Wurtman RJ.

J Biol Chem. 1987 Dec 25;262(36):17487-91.PMID: 3693364 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis of acetylcholine from choline derived from phosphatidylcholine in a human neuronal cell line.

Blusztajn JK, Liscovitch M, Richardson UI.

Proc Natl Acad Sci U S A. 1987 Aug;84(15):5474-7.PMID: 3474663 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate.

Liscovitch M, Blusztajn JK, Freese A, Wurtman RJ.

Biochem J. 1987 Jan 1;241(1):81-6.PMID: 3566713 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylcholine as a precursor of choline for acetylcholine synthesis.

Blusztajn JK, Liscovitch M, Mauron C, Richardson UI, Wurtman RJ.

J Neural Transm Suppl. 1987;24:247-59. Review.PMID: 3316498 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: stimulation by phorbol esters.

Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ.

J Neurochem. 1986 Dec;47(6):1936-41.PMID: 3772385 [PubMed - indexed for MEDLINE]Related articles

"Autocannibalism" of membrane choline-phospholipids: physiology and pathology.

Blusztajn JK, Holbrook PG, Lakher M, Liscovitch M, Maire JC, Mauron C, Richardson UI, Tacconi M, Wurtman RJ.

Psychopharmacol Bull. 1986;22(3):781-6. No abstract available. PMID: 3025910 [PubMed - indexed for MEDLINE]Related articles

Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain.

Blusztajn JK, Zeisel SH, Wurtman RJ.

Biochem J. 1985 Dec 1;232(2):505-11.PMID: 4091805 [PubMed - indexed for MEDLINE]Related articlesFree article

High-performance liquid chromatography of water-soluble choline metabolites.

Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ.

Anal Biochem. 1985 Nov 15;151(1):182-7.PMID: 4091278 [PubMed - indexed for MEDLINE]Related articles

Choline and cholinergic neurons.

Blusztajn JK, Wurtman RJ.

Science. 1983 Aug 12;221(4611):614-20.PMID: 6867732 [PubMed - indexed for MEDLINE]Related articles

Formation of methylamines from ingested choline and lecithin.

Zeisel SH, Wishnok JS, Blusztajn JK.

J Pharmacol Exp Ther. 1983 May;225(2):320-4.PMID: 6842395 [PubMed - indexed for MEDLINE]Related articles

Dopamine stimulation of phosphatidylcholine (lecithin) biosynthesis in rat brain neurons.

Leprohon CE, Blusztajn JK, Wurtman RJ.

Proc Natl Acad Sci U S A. 1983 Apr;80(7):2063-6.PMID: 6572961 [PubMed - indexed for MEDLINE]Related articlesFree article

Choline biosynthesis by a preparation enriched in synaptosomes from rat brain.

Blusztajn JK, Wurtman RJ.

Nature. 1981 Apr 2;290(5805):417-8.PMID: 7219528 [PubMed - indexed for MEDLINE]Related articles

Prenatal diagnosis of neural tube defects. V. The value of amniotic fluid cholinesterase studies.

Zeisel SH, Milunsky A, Blusztajn JK.

Am J Obstet Gynecol. 1980 Jun 15;137(4):481-5.PMID: 6155784 [PubMed - indexed for MEDLINE]Related articles