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Obesity is associated with pain and impaired mobility despite therapy in systemic lupus erythematosus.
Borg A, Lindblom J, Gomez A, Soltani A, Enman Y, Heintz E, Regardt M, Grannas D, Emamikia S, Parodis I. Borg A, et al. Front Med (Lausanne). 2023 Aug 24;10:1247354. doi: 10.3389/fmed.2023.1247354. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37692782 Free PMC article.
OBJECTIVE: To investigate whether abnormal BMI is associated with health-related quality of life (HRQoL) impairments, defined as patient-reported problems within the different dimensions of the three-level EQ-5D (EQ-5D-3L), before and after treatment for active syst …
OBJECTIVE: To investigate whether abnormal BMI is associated with health-related quality of life (HRQoL) impairments, defined as patient-rep …
POSNOC-POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: a randomised controlled trial of axillary treatment in women with early-stage breast cancer who have metastases in one or two sentinel nodes.
Goyal A, Mann GB, Fallowfield L, Duley L, Reed M, Dodwell D, Coleman RE, Fakis A, Newcombe R, Jenkins V, Whitham D, Childs M, Whynes D, Keeley V, Ellis I, Fairbrother P, Sadiq S, Monson K, Montgomery A, Tan W, Vale L, Homer T, Badger H, Haines RH, Lewis M, Megias D, Nabi Z, Singh P, Caraman A, Miles E; POSNOC Trialists. Goyal A, et al. BMJ Open. 2021 Dec 2;11(12):e054365. doi: 10.1136/bmjopen-2021-054365. BMJ Open. 2021. PMID: 34857578 Free PMC article. Clinical Trial.
Secondary outcomes are arm morbidity assessed by Lymphoedema and Breast Cancer Questionnaire and QuickDASH questionnaires; quality of life and anxiety as assessed with FACT B+4 and State/Trait Anxiety Inventory questionnaires, respectively; other oncological outcomes; economic ev …
Secondary outcomes are arm morbidity assessed by Lymphoedema and Breast Cancer Questionnaire and QuickDASH questionnaires; quality of life a …
Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727).
Tovey H, Sipos O, Parker JS, Hoadley KA, Quist J, Kernaghan S, Kilburn L, Salgado R, Loi S, Kennedy RD, Roxanis I, Gazinska P, Pinder SE, Bliss J, Perou CM, Haider S, Grigoriadis A, Tutt A, Cheang MCU. Tovey H, et al. Clin Cancer Res. 2023 Sep 15;29(18):3691-3705. doi: 10.1158/1078-0432.CCR-23-0370. Clin Cancer Res. 2023. PMID: 37574209 Free PMC article.
EQ-5D full health state after therapy heralds reduced hazard to accrue subsequent organ damage in systemic lupus erythematosus.
Lindblom J, Zetterberg S, Emamikia S, Borg A, von Perner G, Enman Y, Heintz E, Regardt M, Grannas D, Gomez A, Parodis I. Lindblom J, et al. Front Med (Lausanne). 2022 Dec 20;9:1092325. doi: 10.3389/fmed.2022.1092325. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36606059 Free PMC article.
In a separate analysis, we sought to investigate associations between experience of "no problems" in each one of the five dimensions of EQ-5D and the risk to accrue damage. METHODS: Data from the open-label extension periods of the BLISS-52 and BLISS-76 trial …
In a separate analysis, we sought to investigate associations between experience of "no problems" in each one of the five dimensions of EQ- …
EQ-5D-3L full health state discriminates between drug and placebo in clinical trials of systemic lupus erythematosus.
Lindblom J, Gomez A, Borg A, Emamikia S, Ladakis D, Matilla J, Pehr M, Cobar F, Enman Y, Heintz E, Regardt M, Parodis I. Lindblom J, et al. Rheumatology (Oxford). 2021 Oct 2;60(10):4703-4716. doi: 10.1093/rheumatology/keab080. Rheumatology (Oxford). 2021. PMID: 33502473 Free PMC article.
OBJECTIVES: The objectives of this study were to investigate the discriminative ability of EQ-5D-3L full health state (FHS) in clinical trials of SLE, and to identify factors associated with FHS after treatment. METHODS: Data from the BLISS-52 (NCT00424476) and B …
OBJECTIVES: The objectives of this study were to investigate the discriminative ability of EQ-5D-3L full health state (FHS) in clinic …
Impact of remission and low disease activity on health-related quality of life in patients with systemic lupus erythematosus.
Emamikia S, Oon S, Gomez A, Lindblom J, Borg A, Enman Y, Morand E, Grannas D, van Vollenhoven RF, Nikpour M, Parodis I. Emamikia S, et al. Rheumatology (Oxford). 2022 Nov 28;61(12):4752-4762. doi: 10.1093/rheumatology/keac185. Rheumatology (Oxford). 2022. PMID: 35302581 Free PMC article.
OBJECTIVES: To investigate the impact of remission and lupus low disease activity state (LLDAS) on health-related quality of life (HRQoL) in systemic lupus erythematosus. METHODS: Short-Form 36 (SF-36), three-level EQ-5D (EQ-5D-3L) and Functional Assessment of Chron …
OBJECTIVES: To investigate the impact of remission and lupus low disease activity state (LLDAS) on health-related quality of life (HRQoL) in …
Sensitivity analysis of EQ-5D-3L index scores in terms of discriminative and known-groups validity in SLE: introducing Adequate Health State.
Hua N, Gomez A, Lindblom J, Emamikia S, Enman Y, Grannas D, Heintz E, Regardt M, Parodis I. Hua N, et al. Rheumatology (Oxford). 2023 Dec 1;62(12):3916-3923. doi: 10.1093/rheumatology/kead140. Rheumatology (Oxford). 2023. PMID: 36946293 Free PMC article.
METHODS: Data from the BLISS-52 (NCT00424476) and BLISS-76 (NCT00410384) trials (N = 1684), which both showed superiority of belimumab to placebo, were utilized. ...EQ-5D index scores less stringent than FHS may be clinically relevant health-related quality o …
METHODS: Data from the BLISS-52 (NCT00424476) and BLISS-76 (NCT00410384) trials (N = 1684), which both showed superiority of b …
Impact of overweight and obesity on patient-reported health-related quality of life in systemic lupus erythematosus.
Gomez A, Hani Butrus F, Johansson P, Åkerström E, Soukka S, Emamikia S, Enman Y, Pettersson S, Parodis I. Gomez A, et al. Rheumatology (Oxford). 2021 Mar 2;60(3):1260-1272. doi: 10.1093/rheumatology/keaa453. Rheumatology (Oxford). 2021. PMID: 32918459 Free PMC article.
We determined the impact of overweight and obesity on HRQoL in a large SLE population. METHODS: We pooled cross-sectional baseline data from the BLISS-52 (NCT00424476) and BLISS-76 (NCT00410384) trials (N = 1684). HRQoL was evaluated using the 36-item Short Form Hea …
We determined the impact of overweight and obesity on HRQoL in a large SLE population. METHODS: We pooled cross-sectional baseline data from …
Use of Antimalarial Agents is Associated with Favourable Physical Functioning in Patients with Systemic Lupus Erythematosus.
Gomez A, Soukka S, Johansson P, Åkerström E, Emamikia S, Enman Y, Chatzidionysiou K, Parodis I. Gomez A, et al. J Clin Med. 2020 Jun 10;9(6):1813. doi: 10.3390/jcm9061813. J Clin Med. 2020. PMID: 32532059 Free PMC article.
Antimalarial agents (AMA) are the cornerstone of SLE therapy, but data on their impact on HRQoL are scarce. We investigated this impact using baseline data from the BLISS-52 (NCT00424476) and BLISS-76 (NCT00410384) trials (n = 1684). HRQoL was self-reported using th …
Antimalarial agents (AMA) are the cornerstone of SLE therapy, but data on their impact on HRQoL are scarce. We investigated this impact usin …
16 results