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Items: 1 to 20 of 317

1.

Structure and dynamics of the aliphatic cholesterol side chain in membranes as studied by (2)H NMR spectroscopy and molecular dynamics simulation.

Vogel A, Scheidt HA, Baek DJ, Bittman R, Huster D.

Phys Chem Chem Phys. 2016 Jan 27;18(5):3730-8. doi: 10.1039/c5cp05084g.

PMID:
26762541
2.

"Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720".

Camp SM, Chiang ET, Sun C, Usatyuk PV, Bittman R, Natarajan V, Garcia JG, Dudek SM.

Chem Phys Lipids. 2016 Jan;194:85-93. doi: 10.1016/j.chemphyslip.2015.10.004. Epub 2015 Oct 29.

PMID:
26496151
3.

Ceramide channel: Structural basis for selective membrane targeting.

Perera MN, Ganesan V, Siskind LJ, Szulc ZM, Bielawska A, Bittman R, Colombini M.

Chem Phys Lipids. 2016 Jan;194:110-6. doi: 10.1016/j.chemphyslip.2015.09.007. Epub 2015 Sep 25.

PMID:
26408265
4.

LAPTM4B facilitates late endosomal ceramide export to control cell death pathways.

Blom T, Li S, Dichlberger A, Bäck N, Kim YA, Loizides-Mangold U, Riezman H, Bittman R, Ikonen E.

Nat Chem Biol. 2015 Oct;11(10):799-806. doi: 10.1038/nchembio.1889. Epub 2015 Aug 17.

PMID:
26280656
5.

Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720.

Camp SM, Chiang ET, Sun C, Usatyuk PV, Bittman R, Natarajan V, Garcia JG, Dudek SM.

Chem Phys Lipids. 2015 Oct;191:16-24. doi: 10.1016/j.chemphyslip.2015.08.004. Epub 2015 Aug 10.

PMID:
26272033
6.

Synthesis and biological activity of alkynoic acids derivatives against mycobacteria.

Vilchèze C, Leung LW, Bittman R, Jacobs WR Jr.

Chem Phys Lipids. 2016 Jan;194:125-38. doi: 10.1016/j.chemphyslip.2015.08.001. Epub 2015 Aug 6.

PMID:
26256431
7.

Synthesis and antiproliferative properties of a new ceramide analog of varacin.

Mahendran A, Ghogare AA, Bittman R, Arthur G, Greer A.

Chem Phys Lipids. 2016 Jan;194:165-70. doi: 10.1016/j.chemphyslip.2015.07.023. Epub 2015 Aug 5.

PMID:
26254858
8.

Synthesis and photochemical properties of PEGylated coumarin-caged ceramides for cell studies.

Kim YA, Day J, Lirette CA, Costain WJ, Johnston LJ, Bittman R.

Chem Phys Lipids. 2016 Jan;194:117-24. doi: 10.1016/j.chemphyslip.2015.07.006. Epub 2015 Jul 19.

PMID:
26200920
9.

Properties of HIV-1 associated cholesterol in addition to raft formation are important for virus infection.

Hawkes D, Jones KL, Smyth RP, Pereira CF, Bittman R, Jaworowski A, Mak J.

Virus Res. 2015 Dec 2;210:18-21. doi: 10.1016/j.virusres.2015.06.023. Epub 2015 Jul 17.

PMID:
26191619
10.

Effect of ether glycerol lipids on interleukin-1β release and experimental autoimmune encephalomyelitis.

Boomkamp SD, Byun HS, Ubhi S, Jiang HR, Pyne S, Bittman R, Pyne NJ.

Chem Phys Lipids. 2016 Jan;194:2-11. doi: 10.1016/j.chemphyslip.2015.07.001. Epub 2015 Jul 14.

PMID:
26187854
11.

Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures.

Schweitzer KS, Chen SX, Law S, Van Demark M, Poirier C, Justice MJ, Hubbard WC, Kim ES, Lai X, Wang M, Kranz WD, Carroll CJ, Ray BD, Bittman R, Goodpaster J, Petrache I.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L175-87. doi: 10.1152/ajplung.00411.2014. Epub 2015 May 15.

PMID:
25979079
12.

Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics.

Woodcock JM, Coolen C, Goodwin KL, Baek DJ, Bittman R, Samuel MS, Pitson SM, Lopez AF.

Oncotarget. 2015 Jun 10;6(16):14522-36.

13.

Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate.

Wang L, Bittman R, Garcia JG, Dudek SM.

Microvasc Res. 2015 May;99:102-9. doi: 10.1016/j.mvr.2015.03.007. Epub 2015 Apr 7.

PMID:
25862132
14.

Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation.

Baudiß K, Ayata CK, Lazar Z, Cicko S, Beckert J, Meyer A, Zech A, Vieira RP, Bittman R, Gómez-Muñoz A, Merfort I, Idzko M.

Eur Respir J. 2015 Jun;45(6):1669-80. doi: 10.1183/09031936.00080014. Epub 2015 Jan 22.

PMID:
25614161
15.

p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.

Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD.

Dev Biol. 2015 Mar 1;399(1):41-53. doi: 10.1016/j.ydbio.2014.12.010. Epub 2014 Dec 16.

16.

Phosphatidic acid inhibits ceramide 1-phosphate-stimulated macrophage migration.

Ouro A, Arana L, Rivera IG, Ordoñez M, Gomez-Larrauri A, Presa N, Simón J, Trueba M, Gangoiti P, Bittman R, Gomez-Muñoz A.

Biochem Pharmacol. 2014 Dec 15;92(4):642-50. doi: 10.1016/j.bcp.2014.10.005. Epub 2014 Oct 18.

PMID:
25450673
17.

Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.

Degagné E, Pandurangan A, Bandhuvula P, Kumar A, Eltanawy A, Zhang M, Yoshinaga Y, Nefedov M, de Jong PJ, Fong LG, Young SG, Bittman R, Ahmedi Y, Saba JD.

J Clin Invest. 2014 Dec;124(12):5368-84. doi: 10.1172/JCI74188. Epub 2014 Oct 27.

18.

Improving Mycobacterium bovis bacillus Calmette-Guèrin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells.

Venkataswamy MM, Ng TW, Kharkwal SS, Carreño LJ, Johnson AJ, Kunnath-Velayudhan S, Liu Z, Bittman R, Jervis PJ, Cox LR, Besra GS, Wen X, Yuan W, Tsuji M, Li X, Ho DD, Chan J, Lee S, Frothingham R, Haynes BF, Panas MW, Gillard GO, Sixsmith JD, Korioth-Schmitz B, Schmitz JE, Larsen MH, Jacobs WR Jr, Porcelli SA.

PLoS One. 2014 Sep 25;9(9):e108383. doi: 10.1371/journal.pone.0108383. eCollection 2014.

19.

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics.

Evangelisti C, Evangelisti C, Teti G, Chiarini F, Falconi M, Melchionda F, Pession A, Bertaina A, Locatelli F, McCubrey JA, Beak DJ, Bittman R, Pyne S, Pyne NJ, Martelli AM.

Oncotarget. 2014 Sep 15;5(17):7886-901.

20.

Membrane properties of cholesterol analogs with an unbranched aliphatic side chain.

Meyer T, Baek DJ, Bittman R, Haralampiev I, Müller P, Herrmann A, Huster D, Scheidt HA.

Chem Phys Lipids. 2014 Dec;184:1-6. doi: 10.1016/j.chemphyslip.2014.08.002. Epub 2014 Aug 27.

PMID:
25173446
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