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Results: 1 to 20 of 30

1.

Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors.

Levy JM, Thompson JC, Griesinger AM, Amani V, Donson AM, Birks DK, Morgan MJ, Mirsky DM, Handler MH, Foreman NK, Thorburn A.

Cancer Discov. 2014 Jul;4(7):773-80. doi: 10.1158/2159-8290.CD-14-0049. Epub 2014 May 13.

PMID:
24823863
[PubMed - in process]
2.

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.

Venkataraman S, Alimova I, Balakrishnan I, Harris P, Birks DK, Griesinger A, Amani V, Cristiano B, Remke M, Taylor MD, Handler M, Foreman NK, Vibhakar R.

Oncotarget. 2014 May 15;5(9):2355-71.

PMID:
24796395
[PubMed - in process]
Free PMC Article
3.

Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.

Harris PS, Venkataraman S, Alimova I, Birks DK, Balakrishnan I, Cristiano B, Donson AM, Dubuc AM, Taylor MD, Foreman NK, Reigan P, Vibhakar R.

Mol Cancer. 2014 Mar 24;13:72. doi: 10.1186/1476-4598-13-72.

PMID:
24661910
[PubMed - in process]
Free PMC Article
4.

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma.

Hoffman LM, Donson AM, Nakachi I, Griesinger AM, Birks DK, Amani V, Hemenway MS, Liu AK, Wang M, Hankinson TC, Handler MH, Foreman NK.

Acta Neuropathol. 2014 May;127(5):731-45. doi: 10.1007/s00401-013-1212-8. Epub 2013 Nov 17.

PMID:
24240813
[PubMed - in process]
5.

Pediatric Brainstem Gangliogliomas Show BRAF(V600E) Mutation in a High Percentage of Cases.

Donson AM, Kleinschmidt-DeMasters BK, Aisner DL, Bemis LT, Birks DK, Levy JM, Smith AA, Handler MH, Foreman NK, Rush SZ.

Brain Pathol. 2014 Mar;24(2):173-83. doi: 10.1111/bpa.12103. Epub 2013 Dec 23.

PMID:
24238153
[PubMed - in process]
6.

Characterization of distinct immunophenotypes across pediatric brain tumor types.

Griesinger AM, Birks DK, Donson AM, Amani V, Hoffman LM, Waziri A, Wang M, Handler MH, Foreman NK.

J Immunol. 2013 Nov 1;191(9):4880-8. doi: 10.4049/jimmunol.1301966. Epub 2013 Sep 27.

PMID:
24078694
[PubMed - indexed for MEDLINE]
7.

Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.

Barton VN, Donson AM, Birks DK, Kleinschmidt-DeMasters BK, Handler MH, Foreman NK, Rush SZ.

J Neuropathol Exp Neurol. 2013 May;72(5):442-9. doi: 10.1097/NEN.0b013e31829023dd.

PMID:
23584203
[PubMed - indexed for MEDLINE]
8.

Epithelioid GBMs show a high percentage of BRAF V600E mutation.

Kleinschmidt-DeMasters BK, Aisner DL, Birks DK, Foreman NK.

Am J Surg Pathol. 2013 May;37(5):685-98. doi: 10.1097/PAS.0b013e31827f9c5e.

PMID:
23552385
[PubMed - indexed for MEDLINE]
9.

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes.

Birks DK, Donson AM, Patel PR, Sufit A, Algar EM, Dunham C, Kleinschmidt-DeMasters BK, Handler MH, Vibhakar R, Foreman NK.

Pediatr Blood Cancer. 2013 Jul;60(7):1095-102. doi: 10.1002/pbc.24481. Epub 2013 Feb 4.

PMID:
23382118
[PubMed - indexed for MEDLINE]
10.

MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.

Venkataraman S, Birks DK, Balakrishnan I, Alimova I, Harris PS, Patel PR, Handler MH, Dubuc A, Taylor MD, Foreman NK, Vibhakar R.

J Biol Chem. 2013 Jan 18;288(3):1918-28. doi: 10.1074/jbc.M112.396762. Epub 2012 Dec 4.

PMID:
23212916
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.

Alimova I, Birks DK, Harris PS, Knipstein JA, Venkataraman S, Marquez VE, Foreman NK, Vibhakar R.

Neuro Oncol. 2013 Feb;15(2):149-60. doi: 10.1093/neuonc/nos285. Epub 2012 Nov 28.

PMID:
23190500
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells.

Whiteway SL, Harris PS, Venkataraman S, Alimova I, Birks DK, Donson AM, Foreman NK, Vibhakar R.

J Neurooncol. 2013 Jan;111(2):113-21. doi: 10.1007/s11060-012-1000-7. Epub 2012 Nov 9.

PMID:
23138228
[PubMed - indexed for MEDLINE]
13.

Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.

Donson AM, Birks DK, Schittone SA, Kleinschmidt-DeMasters BK, Sun DY, Hemenway MF, Handler MH, Waziri AE, Wang M, Foreman NK.

J Immunol. 2012 Aug 15;189(4):1920-7. doi: 10.4049/jimmunol.1103373. Epub 2012 Jul 16.

PMID:
22802421
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas.

Sufit A, Donson AM, Birks DK, Knipstein JA, Fenton LZ, Jedlicka P, Hankinson TC, Handler MH, Foreman NK.

J Neurosurg Pediatr. 2012 Aug;10(2):81-8. doi: 10.3171/2012.3.PEDS11316. Epub 2012 Jun 29.

PMID:
22747092
[PubMed - indexed for MEDLINE]
15.

Clinical and molecular characteristics of congenital glioblastoma.

Macy ME, Birks DK, Barton VN, Chan MH, Donson AM, Kleinschmidt-Demasters BK, Bemis LT, Handler MH, Foreman NK.

Neuro Oncol. 2012 Jul;14(7):931-41. doi: 10.1093/neuonc/nos125. Epub 2012 Jun 18.

PMID:
22711608
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Pediatric brainstem gangliogliomas show overexpression of neuropeptide prepronociceptin (PNOC) by microarray and immunohistochemistry.

Chan MH, Kleinschmidt-Demasters BK, Donson AM, Birks DK, Foreman NK, Rush SZ.

Pediatr Blood Cancer. 2012 Dec 15;59(7):1173-9. doi: 10.1002/pbc.24232. Epub 2012 Jun 15.

PMID:
22706982
[PubMed - indexed for MEDLINE]
17.

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.

Harris PS, Venkataraman S, Alimova I, Birks DK, Donson AM, Knipstein J, Dubuc A, Taylor MD, Handler MH, Foreman NK, Vibhakar R.

BMC Cancer. 2012 Mar 5;12:80. doi: 10.1186/1471-2407-12-80.

PMID:
22390279
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Atypical teratoid rhabdoid tumors (ATRTs): the British Columbia's Children's Hospital's experience, 1986-2006.

Fleming AJ, Hukin J, Rassekh R, Fryer C, Kim J, Stemmer-Rachamimov A, Birks DK, Huang A, Yip S, Dunham C.

Brain Pathol. 2012 Sep;22(5):625-35. doi: 10.1111/j.1750-3639.2011.00561.x. Epub 2012 Feb 13.

PMID:
22188464
[PubMed - indexed for MEDLINE]
19.

Histone deacetylase inhibition decreases proliferation and potentiates the effect of ionizing radiation in atypical teratoid/rhabdoid tumor cells.

Knipstein JA, Birks DK, Donson AM, Alimova I, Foreman NK, Vibhakar R.

Neuro Oncol. 2012 Feb;14(2):175-83. doi: 10.1093/neuonc/nor208. Epub 2011 Dec 8.

PMID:
22156471
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Atypical teratoid/rhabdoid tumor arising in a ganglioglioma: genetic characterization.

Kleinschmidt-DeMasters BK, Birks DK, Aisner DL, Hankinson TC, Rosenblum MK.

Am J Surg Pathol. 2011 Dec;35(12):1894-901. doi: 10.1097/PAS.0b013e3182382a3f.

PMID:
22082607
[PubMed - indexed for MEDLINE]

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