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Results: 1 to 20 of 126

1.

Reactivity to N-terminally truncated GAD65(96-585) identifies GAD autoantibodies that are more closely associated with diabetes progression in relatives of patients with type 1 diabetes.

Williams AJ, Lampasona V, Wyatt R, Brigatti C, Gillespie KM, Bingley PJ, Achenbach P.

Diabetes. 2015 May 22. pii: db141694. [Epub ahead of print]

PMID:
26001397
2.

Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial.

Bonifacio E, Ziegler AG, Klingensmith G, Schober E, Bingley PJ, Rottenkolber M, Theil A, Eugster A, Puff R, Peplow C, Buettner F, Lange K, Hasford J, Achenbach P; Pre-POINT Study Group.

JAMA. 2015 Apr 21;313(15):1541-9. doi: 10.1001/jama.2015.2928.

PMID:
25898052
3.

Novel association between immune-mediated susceptibility loci and persistent autoantibody positivity in type 1 diabetes.

Brorsson CA, Onengut S, Chen WM, Wenzlau J, Yu L, Baker P, Williams AJ, Bingley PJ, Hutton JC, Eisenbarth GS, Concannon P, Rich SS, Pociot F; Type 1 Diabetes Genetics Consortium.

Diabetes. 2015 Mar 31. pii: db141730. [Epub ahead of print]

PMID:
25829454
4.

Seasonal variation in month of diagnosis in children with type 1 diabetes registered in 23 European centers during 1989-2008: little short-term influence of sunshine hours or average temperature.

Patterson C, Gyürüs E, Rosenbauer J, Cinek O, Neu A, Schober E, Parslow R, Joner G, Svensson J, Castell C, Bingley P, Schoenle E, Jarosz-Chobot P, Urbonaité B, Rothe U, Kržišnik C, Ionescu-Tirgoviste C, Weets I, Kocova M, Stipancic G, Samardzic M, de Beaufort C, Green A, Soltész G, Dahlquist G.

Pediatr Diabetes. 2014 Oct 15. doi: 10.1111/pedi.12227. [Epub ahead of print]

PMID:
25316271
5.

β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure.

Skowera A, Ladell K, McLaren JE, Dolton G, Matthews KK, Gostick E, Kronenberg-Versteeg D, Eichmann M, Knight RR, Heck S, Powrie J, Bingley PJ, Dayan CM, Miles JJ, Sewell AK, Price DA, Peakman M.

Diabetes. 2015 Mar;64(3):916-25. doi: 10.2337/db14-0332. Epub 2014 Sep 23.

PMID:
25249579
6.

Risk of pediatric celiac disease according to HLA haplotype and country.

Liu E, Lee HS, Aronsson CA, Hagopian WA, Koletzko S, Rewers MJ, Eisenbarth GS, Bingley PJ, Bonifacio E, Simell V, Agardh D; TEDDY Study Group.

N Engl J Med. 2014 Jul 3;371(1):42-9. doi: 10.1056/NEJMoa1313977. Erratum in: N Engl J Med. 2014 Jul 24;371(4):390.

7.

Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes.

Arif S, Leete P, Nguyen V, Marks K, Nor NM, Estorninho M, Kronenberg-Versteeg D, Bingley PJ, Todd JA, Guy C, Dunger DB, Powrie J, Willcox A, Foulis AK, Richardson SJ, de Rinaldis E, Morgan NG, Lorenc A, Peakman M.

Diabetes. 2014 Nov;63(11):3835-45. doi: 10.2337/db14-0365. Epub 2014 Jun 17.

8.

Islet autoantibody testing: an end to the trials and tribulations?

Bingley PJ, Williams AJ.

Diabetes. 2013 Dec;62(12):4009-11. doi: 10.2337/db13-1445. No abstract available.

9.

Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings.

Gillespie KM, Aitken RJ, Wilson I, Williams AJ, Bingley PJ.

Diabetes. 2014 Mar;63(3):1041-7. doi: 10.2337/db13-0994. Epub 2013 Nov 7.

10.

Humoral responses to islet antigen-2 and zinc transporter 8 are attenuated in patients carrying HLA-A*24 alleles at the onset of type 1 diabetes.

Long AE, Gillespie KM, Aitken RJ, Goode JC, Bingley PJ, Williams AJ.

Diabetes. 2013 Jun;62(6):2067-71. doi: 10.2337/db12-1468. Epub 2013 Feb 8.

11.

Early-onset, coexisting autoimmunity and decreased HLA-mediated susceptibility are the characteristics of diabetes in Down syndrome.

Aitken RJ, Mehers KL, Williams AJ, Brown J, Bingley PJ, Holl RW, Rohrer TR, Schober E, Abdul-Rasoul MM, Shield JP, Gillespie KM.

Diabetes Care. 2013 May;36(5):1181-5. doi: 10.2337/dc12-1712. Epub 2012 Dec 28.

12.

The core cysteines, (C909) of islet antigen-2 and (C945) of islet antigen-2β, are crucial to autoantibody binding in type 1 diabetes.

Elvers KT, Geoghegan I, Shoemark DK, Lampasona V, Bingley PJ, Williams AJ.

Diabetes. 2013 Jan;62(1):214-22. doi: 10.2337/db11-1590. Epub 2012 Sep 10.

13.

Trends in childhood type 1 diabetes incidence in Europe during 1989-2008: evidence of non-uniformity over time in rates of increase.

Patterson CC, Gyürüs E, Rosenbauer J, Cinek O, Neu A, Schober E, Parslow RC, Joner G, Svensson J, Castell C, Bingley PJ, Schoenle E, Jarosz-Chobot P, Urbonaité B, Rothe U, Krzisnik C, Ionescu-Tirgoviste C, Weets I, Kocova M, Stipancic G, Samardzic M, de Beaufort CE, Green A, Dahlquist GG, Soltész G.

Diabetologia. 2012 Aug;55(8):2142-7. doi: 10.1007/s00125-012-2571-8. Epub 2012 May 26.

PMID:
22638547
14.

Worth the wait: type 1 diabetes prospective birth cohort studies enter adolescence.

Williams AJ, Bingley PJ.

Diabetologia. 2012 Jul;55(7):1873-6. doi: 10.1007/s00125-012-2583-4. Epub 2012 May 20.

PMID:
22610401
15.

Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies.

Yu L, Boulware DC, Beam CA, Hutton JC, Wenzlau JM, Greenbaum CJ, Bingley PJ, Krischer JP, Sosenko JM, Skyler JS, Eisenbarth GS, Mahon JL; Type 1 Diabetes TrialNet Study Group.

Diabetes Care. 2012 Jun;35(6):1213-8. doi: 10.2337/dc11-2081. Epub 2012 Mar 23.

16.

Systematic assessment of etiology in adults with a clinical diagnosis of young-onset type 2 diabetes is a successful strategy for identifying maturity-onset diabetes of the young.

Thanabalasingham G, Pal A, Selwood MP, Dudley C, Fisher K, Bingley PJ, Ellard S, Farmer AJ, McCarthy MI, Owen KR.

Diabetes Care. 2012 Jun;35(6):1206-12. doi: 10.2337/dc11-1243. Epub 2012 Mar 19.

17.

Rising incidence of type 1 diabetes is associated with altered immunophenotype at diagnosis.

Long AE, Gillespie KM, Rokni S, Bingley PJ, Williams AJ.

Diabetes. 2012 Mar;61(3):683-6. doi: 10.2337/db11-0962. Epub 2012 Feb 7.

18.

The role of autoantibodies to zinc transporter 8 in prediction of type 1 diabetes in relatives: lessons from the European Nicotinamide Diabetes Intervention Trial (ENDIT) cohort.

Long AE, Gooneratne AT, Rokni S, Williams AJ, Bingley PJ.

J Clin Endocrinol Metab. 2012 Feb;97(2):632-7. doi: 10.1210/jc.2011-1952. Epub 2011 Dec 7.

PMID:
22162482
19.

'Insulin autoantibody affinity measurement using a single concentration of unlabelled insulin competitor discriminates risk in relatives of patients with type 1 diabetes.

Curnock RM, Reed CR, Rokni S, Broadhurst JW, Bingley PJ, Williams AJ.

Clin Exp Immunol. 2012 Jan;167(1):67-72. doi: 10.1111/j.1365-2249.2011.04495.x.

20.

Diabetes Antibody Standardization Program: First evaluation of assays for autoantibodies to IA-2β.

Schlosser M, Mueller PW, Achenbach P, Lampasona V, Bingley PJ; Participating Laboratories.

Diabetes Care. 2011 Nov;34(11):2410-2. doi: 10.2337/dc11-1161. Epub 2011 Sep 16.

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