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Items: 1 to 20 of 102


Chernobyl cleanup workers from Estonia: cohort description and related epidemiological research.

Rahu K, Rahu M, Tekkel M, Veidebaum T, Hakulinen T, Auvinen A, Bigbee WL, Hartshorne MF, Inskip PD, Boice JD Jr.

J Radiol Prot. 2015 Dec;35(4):R35-45. doi: 10.1088/0952-4746/35/4/R35. Epub 2015 Oct 29.


Validation of a blood protein signature for non-small cell lung cancer.

Mehan MR, Williams SA, Siegfried JM, Bigbee WL, Weissfeld JL, Wilson DO, Pass HI, Rom WN, Muley T, Meister M, Franklin W, Miller YE, Brody EN, Ostroff RM.

Clin Proteomics. 2014 Aug 1;11(1):32. doi: 10.1186/1559-0275-11-32. eCollection 2014.


Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma.

Zaidi AH, Gopalakrishnan V, Kasi PM, Zeng X, Malhotra U, Balasubramanian J, Visweswaran S, Sun M, Flint MS, Davison JM, Hood BL, Conrads TP, Bergman JJ, Bigbee WL, Jobe BA.

Cancer. 2014 Dec 15;120(24):3902-13. doi: 10.1002/cncr.28963. Epub 2014 Aug 5.


Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration.

McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, Conley BA.

BMC Med. 2013 Oct 17;11:220. doi: 10.1186/1741-7015-11-220.


Criteria for the use of omics-based predictors in clinical trials.

McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, Conley BA.

Nature. 2013 Oct 17;502(7471):317-20. doi: 10.1038/nature12564.


Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study.

Seymour CW, Yende S, Scott MJ, Pribis J, Mohney RP, Bell LN, Chen YF, Zuckerbraun BS, Bigbee WL, Yealy DM, Weissfeld L, Kellum JA, Angus DC.

Intensive Care Med. 2013 Aug;39(8):1423-34. doi: 10.1007/s00134-013-2935-7. Epub 2013 May 15.


Automated lobe-based airway labeling.

Gu S, Wang Z, Siegfried JM, Wilson D, Bigbee WL, Pu J.

Int J Biomed Imaging. 2012;2012:382806. doi: 10.1155/2012/382806. Epub 2012 Oct 9.


Three-dimensional airway tree architecture and pulmonary function.

Pu J, Leader JK, Meng X, Whiting B, Wilson D, Sciurba FC, Reilly JJ, Bigbee WL, Siegfried J, Gur D.

Acad Radiol. 2012 Nov;19(11):1395-401. doi: 10.1016/j.acra.2012.06.007. Epub 2012 Aug 11.


Identification of pulmonary fissures using a piecewise plane fitting algorithm.

Gu S, Wilson D, Wang Z, Bigbee WL, Siegfried J, Gur D, Pu J.

Comput Med Imaging Graph. 2012 Oct;36(7):560-71. doi: 10.1016/j.compmedimag.2012.06.001. Epub 2012 Jun 29.


A multiplexed serum biomarker immunoassay panel discriminates clinical lung cancer patients from high-risk individuals found to be cancer-free by CT screening.

Bigbee WL, Gopalakrishnan V, Weissfeld JL, Wilson DO, Dacic S, Lokshin AE, Siegfried JM.

J Thorac Oncol. 2012 Apr;7(4):698-708. doi: 10.1097/JTO.0b013e31824ab6b0.


Serum biomarker profiles as diagnostic tools in lung cancer.

Nolen BM, Langmead CJ, Choi S, Lomakin A, Marrangoni A, Bigbee WL, Weissfeld JL, Wilson DO, Dacic S, Siegfried JM, Lokshin AE.

Cancer Biomark. 2011-2012;10(1):3-12. doi: 10.3233/CBM-2012-0229.


A metaproteomic approach to study human-microbial ecosystems at the mucosal luminal interface.

Li X, LeBlanc J, Truong A, Vuthoori R, Chen SS, Lustgarten JL, Roth B, Allard J, Ippoliti A, Presley LL, Borneman J, Bigbee WL, Gopalakrishnan V, Graeber TG, Elashoff D, Braun J, Goodglick L.

PLoS One. 2011;6(11):e26542. doi: 10.1371/journal.pone.0026542. Epub 2011 Nov 21.


Relative quantitation of proteins in expressed prostatic secretion with a stable isotope labeled secretome standard.

Zhao T, Zeng X, Bateman NW, Sun M, Teng PN, Bigbee WL, Dhir R, Nelson JB, Conrads TP, Hood BL.

J Proteome Res. 2012 Feb 3;11(2):1089-99. doi: 10.1021/pr200829f. Epub 2011 Dec 1.


Transfer learning of classification rules for biomarker discovery and verification from molecular profiling studies.

Ganchev P, Malehorn D, Bigbee WL, Gopalakrishnan V.

J Biomed Inform. 2011 Dec;44 Suppl 1:S17-23. doi: 10.1016/j.jbi.2011.04.009. Epub 2011 May 6.


Lung cancer serum biomarker discovery using label-free liquid chromatography-tandem mass spectrometry.

Zeng X, Hood BL, Zhao T, Conrads TP, Sun M, Gopalakrishnan V, Grover H, Day RS, Weissfeld JL, Wilson DO, Siegfried JM, Bigbee WL.

J Thorac Oncol. 2011 Apr;6(4):725-34. doi: 10.1097/JTO.0b013e31820c312e.


Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer.

Ostroff RM, Bigbee WL, Franklin W, Gold L, Mehan M, Miller YE, Pass HI, Rom WN, Siegfried JM, Stewart A, Walker JJ, Weissfeld JL, Williams S, Zichi D, Brody EN.

PLoS One. 2010 Dec 7;5(12):e15003. doi: 10.1371/journal.pone.0015003.


Lung cancer serum biomarker discovery using glycoprotein capture and liquid chromatography mass spectrometry.

Zeng X, Hood BL, Sun M, Conrads TP, Day RS, Weissfeld JL, Siegfried JM, Bigbee WL.

J Proteome Res. 2010 Dec 3;9(12):6440-9. doi: 10.1021/pr100696n. Epub 2010 Oct 28.


Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR.

Ostrow KL, Hoque MO, Loyo M, Brait M, Greenberg A, Siegfried JM, Grandis JR, Gaither Davis A, Bigbee WL, Rom W, Sidransky D.

Clin Cancer Res. 2010 Jul 1;16(13):3463-72. doi: 10.1158/1078-0432.CCR-09-3304. Epub 2010 Jun 30.


Cigarette smoking during pregnancy: chromosome translocations and phenotypic susceptibility in mothers and newborns.

Bennett LM, Wang Y, Ramsey MJ, Harger GF, Bigbee WL, Tucker JD.

Mutat Res. 2010 Feb;696(1):81-8. doi: 10.1016/j.mrgentox.2009.12.015. Epub 2010 Jan 7.


A HUPO test sample study reveals common problems in mass spectrometry-based proteomics.

Bell AW, Deutsch EW, Au CE, Kearney RE, Beavis R, Sechi S, Nilsson T, Bergeron JJ; HUPO Test Sample Working Group.

Nat Methods. 2009 Jun;6(6):423-30. doi: 10.1038/nmeth.1333.

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