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Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer.

Clarke K, Daubon T, Turan N, Soulet F, Mohd Zahari M, Ryan KR, Durant S, He S, Herbert J, Ankers J, Heath JK, Bjerkvig R, Bicknell R, Hotchin NA, Bikfalvi A, Falciani F.

PLoS Genet. 2015 Jul 1;11(7):e1005325. doi: 10.1371/journal.pgen.1005325. eCollection 2015 Jul.


FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis.

Yakkundi A, Bennett R, Hernández-Negrete I, Delalande JM, Hanna M, Lyubomska O, Arthur K, Short A, McKeen H, Nelson L, McCrudden CM, McNally R, McClements L, McCarthy HO, Burns AJ, Bicknell R, Kissenpfennig A, Robson T.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):845-54. doi: 10.1161/ATVBAHA.114.304539. Epub 2015 Mar 12.


Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth.

Noy PJ, Lodhia P, Khan K, Zhuang X, Ward DG, Verissimo AR, Bacon A, Bicknell R.

Oncogene. 2015 Mar 9. doi: 10.1038/onc.2015.34. [Epub ahead of print]


Effect of implant geometry on range of motion in reverse shoulder arthroplasty assessed using glenohumeral separation distance.

North LR, Hetzler MA, Pickell M, Bryant JT, Deluzio KJ, Bicknell RT.

J Shoulder Elbow Surg. 2015 Feb 25. pii: S1058-2746(15)00017-8. doi: 10.1016/j.jse.2014.12.031. [Epub ahead of print]


Comparing conventional and computer-assisted surgery baseplate and screw placement in reverse shoulder arthroplasty.

Venne G, Rasquinha BJ, Pichora D, Ellis RE, Bicknell R.

J Shoulder Elbow Surg. 2015 Jul;24(7):1112-9. doi: 10.1016/j.jse.2014.10.012. Epub 2015 Jan 1.


Identification of novel vascular targets in lung cancer.

Zhuang X, Herbert JM, Lodhia P, Bradford J, Turner AM, Newby PM, Thickett D, Naidu U, Blakey D, Barry S, Cross DA, Bicknell R.

Br J Cancer. 2015 Feb 3;112(3):485-94. doi: 10.1038/bjc.2014.626. Epub 2014 Dec 23.


The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer.

Ward ST, Li KK, Hepburn E, Weston CJ, Curbishley SM, Reynolds GM, Hejmadi RK, Bicknell R, Eksteen B, Ismail T, Rot A, Adams DH.

Br J Cancer. 2015 Jan 20;112(2):319-28. doi: 10.1038/bjc.2014.572. Epub 2014 Nov 18.


Computer navigation and patient-specific instrumentation in shoulder arthroplasty.

Verborgt O, Vanhees M, Heylen S, Hardy P, Declercq G, Bicknell R.

Sports Med Arthrosc. 2014 Dec;22(4):e42-9. doi: 10.1097/JSA.0000000000000045. Review.


Robo4 vaccines induce antibodies that retard tumor growth.

Zhuang X, Ahmed F, Zhang Y, Ferguson HJ, Steele JC, Steven NM, Nagy Z, Heath VL, Toellner KM, Bicknell R.

Angiogenesis. 2015 Jan;18(1):83-95. doi: 10.1007/s10456-014-9448-z. Epub 2014 Oct 28.


In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism.

Packham IM, Watson SP, Bicknell R, Egginton S.

PLoS One. 2014 Sep 19;9(9):e107503. doi: 10.1371/journal.pone.0107503. eCollection 2014.


Differential cavitation, angiogenesis and wound-healing responses in injured mouse and rat spinal cords.

Surey S, Berry M, Logan A, Bicknell R, Ahmed Z.

Neuroscience. 2014 Sep 5;275:62-80. doi: 10.1016/j.neuroscience.2014.06.003. Epub 2014 Jun 11.


RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly.

Wilson E, Leszczynska K, Poulter NS, Edelmann F, Salisbury VA, Noy PJ, Bacon A, Rappoport JZ, Heath JK, Bicknell R, Heath VL.

J Cell Sci. 2014 Jul 15;127(Pt 14):3039-51. doi: 10.1242/jcs.140434. Epub 2014 Jun 13.


Electroporation and microinjection successfully deliver single-stranded and duplex DNA into live cells as detected by FRET measurements.

Bamford RA, Zhao ZY, Hotchin NA, Styles IB, Nash GB, Tucker JH, Bicknell R.

PLoS One. 2014 Apr 22;9(4):e95097. doi: 10.1371/journal.pone.0095097. eCollection 2014.


Shear stress regulated gene expression and angiogenesis in vascular endothelium.

Wragg JW, Durant S, McGettrick HM, Sample KM, Egginton S, Bicknell R.

Microcirculation. 2014 May;21(4):290-300. doi: 10.1111/micc.12119. Review.


Vaccination against tumour blood vessels in colorectal cancer.

Ferguson HJ, Wragg J, Ismail T, Bicknell R.

Eur J Surg Oncol. 2014 Feb;40(2):133-6. doi: 10.1016/j.ejso.2013.11.025. Epub 2013 Dec 13. No abstract available.


Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5.

Exertier P, Javerzat S, Wang B, Franco M, Herbert J, Platonova N, Winandy M, Pujol N, Nivelles O, Ormenese S, Godard V, Becker J, Bicknell R, Pineau R, Wilting J, Bikfalvi A, Hagedorn M.

Oncotarget. 2013 Dec;4(12):2302-16.


Dysfunction of the mTOR pathway is a risk factor for Alzheimer's disease.

Yates SC, Zafar A, Hubbard P, Nagy S, Durant S, Bicknell R, Wilcock G, Christie S, Esiri MM, Smith AD, Nagy Z.

Acta Neuropathol Commun. 2013 May 8;1:3. doi: 10.1186/2051-5960-1-3.


From the unstable painful shoulder to multidirectional instability in the young athlete.

Ren H, Bicknell RT.

Clin Sports Med. 2013 Oct;32(4):815-23. doi: 10.1016/j.csm.2013.07.014. Review.


Paracrine signals from liver sinusoidal endothelium regulate hepatitis C virus replication.

Rowe IA, Galsinh SK, Wilson GK, Parker R, Durant S, Lazar C, Branza-Nichita N, Bicknell R, Adams DH, Balfe P, McKeating JA.

Hepatology. 2014 Feb;59(2):375-84. doi: 10.1002/hep.26571. Epub 2013 Dec 18.


Mapping the extracellular and membrane proteome associated with the vasculature and the stroma in the embryo.

Soulet F, Kilarski WW, Roux-Dalvai F, Herbert JM, Sacewicz I, Mouton-Barbosa E, Bicknell R, Lalor P, Monsarrat B, Bikfalvi A.

Mol Cell Proteomics. 2013 Aug;12(8):2293-312. doi: 10.1074/mcp.M112.024075. Epub 2013 May 14.

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