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Items: 1 to 20 of 105

1.

META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies.

Rosenberger A, Friedrichs S, Amos CI, Brennan P, Fehringer G, Heinrich J, Hung RJ, Muley T, Müller-Nurasyid M, Risch A, Bickeböller H.

PLoS One. 2015 Oct 26;10(10):e0140179. doi: 10.1371/journal.pone.0140179. eCollection 2015.

2.

The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation.

Isernhagen A, Malzahn D, Viktorova E, Elsner L, Monecke S, von Bonin F, Kilisch M, Wermuth JM, Walther N, Balavarca Y, Stahl-Hennig C, Engelke M, Walter L, Bickeböller H, Kube D, Wulf G, Dressel R.

EMBO Mol Med. 2015 Oct 19;7(11):1480-502. doi: 10.15252/emmm.201505246.

3.

Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions.

Qian DC, Byun J, Han Y, Greene CS, Field JK, Hung RJ, Brhane Y, Mclaughlin JR, Fehringer G, Landi MT, Rosenberger A, Bickeböller H, Malhotra J, Risch A, Heinrich J, Hunter DJ, Henderson BE, Haiman CA, Schumacher FR, Eeles RA, Easton DF, Seminara D, Amos CI.

Hum Mol Genet. 2015 Dec 20;24(25):7406-20. doi: 10.1093/hmg/ddv440. Epub 2015 Oct 19.

PMID:
26483192
4.

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence.

Hancock DB, Reginsson GW, Gaddis NC, Chen X, Saccone NL, Lutz SM, Qaiser B, Sherva R, Steinberg S, Zink F, Stacey SN, Glasheen C, Chen J, Gu F, Frederiksen BN, Loukola A, Gudbjartsson DF, Brüske I, Landi MT, Bickeböller H, Madden P, Farrer L, Kaprio J, Kranzler HR, Gelernter J, Baker TB, Kraft P, Amos CI, Caporaso NE, Hokanson JE, Bierut LJ, Thorgeirsson TE, Johnson EO, Stefansson K.

Transl Psychiatry. 2015 Oct 6;5:e651. doi: 10.1038/tp.2015.149.

PMID:
26440539
5.

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia.

Brenner DR, Amos CI, Brhane Y, Timofeeva MN, Caporaso N, Wang Y, Christiani DC, Bickeböller H, Yang P, Albanes D, Stevens VL, Gapstur S, McKay J, Boffetta P, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Skorpen F, Gabrielsen ME, Vatten L, Njølstad I, Chen C, Goodman G, Lathrop M, Vooder T, Välk K, Nelis M, Metspalu A, Broderick P, Eisen T, Wu X, Zhang D, Chen W, Spitz MR, Wei Y, Su L, Xie D, She J, Matsuo K, Matsuda F, Ito H, Risch A, Heinrich J, Rosenberger A, Muley T, Dienemann H, Field JK, Raji O, Chen Y, Gosney J, Liloglou T, Davies MP, Marcus M, McLaughlin J, Orlow I, Han Y, Li Y, Zong X, Johansson M; EPIC Investigators, Liu G, Tworoger SS, Le Marchand L, Henderson BE, Wilkens LR, Dai J, Shen H, Houlston RS, Landi MT, Brennan P, Hung RJ.

Carcinogenesis. 2015 Nov;36(11):1314-26. doi: 10.1093/carcin/bgv128. Epub 2015 Sep 10.

PMID:
26363033
6.

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer.

Hung RJ, Ulrich CM, Goode EL, Brhane Y, Muir K, Chan AT, Marchand LL, Schildkraut J, Witte JS, Eeles R, Boffetta P, Spitz MR, Poirier JG, Rider DN, Fridley BL, Chen Z, Haiman C, Schumacher F, Easton DF, Landi MT, Brennan P, Houlston R, Christiani DC, Field JK, Bickeböller H, Risch A, Kote-Jarai Z, Wiklund F, Grönberg H, Chanock S, Berndt SI, Kraft P, Lindström S, Al Olama AA, Song H, Phelan C, Wentzensen N, Peters U, Slattery ML; GECCO, Sellers TA; FOCI, Casey G, Gruber SB; CORECT, Hunter DJ; DRIVE, Amos CI, Henderson B; GAME-ON Network.

J Natl Cancer Inst. 2015 Aug 29;107(11). pii: djv246. doi: 10.1093/jnci/djv246. Print 2015 Nov.

PMID:
26319099
7.

Predicting survival using clinical risk scores and non-HLA immunogenetics.

Balavarca Y, Pearce K, Norden J, Collin M, Jackson G, Holler E, Dressel R, Kolb HJ, Greinix H, Socie G, Toubert A, Rocha V, Gluckman E, Hromadnikova I, Sedlacek P, Wolff D, Holtick U, Dickinson A, Bickeböller H.

Bone Marrow Transplant. 2015 Nov;50(11):1445-52. doi: 10.1038/bmt.2015.173. Epub 2015 Jul 27.

PMID:
26214138
8.

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study.

Zhang C, Doherty JA, Burgess S, Hung RJ, Lindström S, Kraft P, Gong J, Amos CI, Sellers TA, Monteiro AN, Chenevix-Trench G, Bickeböller H, Risch A, Brennan P, Mckay JD, Houlston RS, Landi MT, Timofeeva MN, Wang Y, Heinrich J, Kote-Jarai Z, Eeles RA, Muir K, Wiklund F, Grönberg H, Berndt SI, Chanock SJ, Schumacher F, Haiman CA, Henderson BE, Amin Al Olama A, Andrulis IL, Hopper JL, Chang-Claude J, John EM, Malone KE, Gammon MD, Ursin G, Whittemore AS, Hunter DJ, Gruber SB, Knight JA, Hou L, Le Marchand L, Newcomb PA, Hudson TJ, Chan AT, Li L, Woods MO, Ahsan H, Pierce BL; GECCO and GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI, and TRICL.

Hum Mol Genet. 2015 Sep 15;24(18):5356-66. doi: 10.1093/hmg/ddv252. Epub 2015 Jul 2.

9.

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.

Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Lutz S, Rosenberger A, Aben KK, Andrew AS, Breslau N, Chang SC, Dieffenbach AK, Dienemann H, Frederiksen B, Han J, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden HF, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Heinrich J, Hokanson JE, Hunter DJ, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare D, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Kraft P, Amos CI, Bierut LJ.

J Natl Cancer Inst. 2015 Apr 14;107(5). pii: djv100. doi: 10.1093/jnci/djv100. Print 2015 May. Review.

PMID:
25873736
10.

Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer.

Poirier JG, Brennan P, McKay JD, Spitz MR, Bickeböller H, Risch A, Liu G, Le Marchand L, Tworoger S, McLaughlin J, Rosenberger A, Heinrich J, Brüske I, Muley T, Henderson BE, Wilkens LR, Zong X, Li Y, Hao K, Timens W, Bossé Y, Sin DD, Obeidat M, Amos CI, Hung RJ.

Genet Epidemiol. 2015 Mar;39(3):197-206. doi: 10.1002/gepi.21882. Epub 2015 Jan 19.

11.

Kernel score statistic for dependent data.

Malzahn D, Friedrichs S, Rosenberger A, Bickeböller H.

BMC Proc. 2014 Jun 17;8(Suppl 1):S41. doi: 10.1186/1753-6561-8-S1-S41. eCollection 2014.

12.

Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees.

Bickeböller H, Bailey JN, Beyene J, Cantor RM, Cordell HJ, Culverhouse RC, Engelman CD, Fardo DW, Ghosh S, König IR, Lorenzo Bermejo J, Melton PE, Santorico SA, Satten GA, Sun L, Tintle NL, Ziegler A, MacCluer JW, Almasy L.

BMC Proc. 2014 Jun 17;8(Suppl 1):S1. doi: 10.1186/1753-6561-8-S1-S1. eCollection 2014.

13.

Genetic factors in individual radiation sensitivity.

Hornhardt S, Rößler U, Sauter W, Rosenberger A, Illig T, Bickeböller H, Wichmann HE, Gomolka M.

DNA Repair (Amst). 2014 Apr;16:54-65. doi: 10.1016/j.dnarep.2014.02.001. Epub 2014 Mar 4.

PMID:
24674628
14.

Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R.

Malzahn D, Müller-Nurasyid M, Heid IM, Wichmann HE; KORA study group, Bickeböller H.

Eur J Hum Genet. 2014 Oct;22(10):1217-24. doi: 10.1038/ejhg.2014.3. Epub 2014 Feb 12.

15.

A network-based kernel machine test for the identification of risk pathways in genome-wide association studies.

Freytag S, Manitz J, Schlather M, Kneib T, Amos CI, Risch A, Chang-Claude J, Heinrich J, Bickeböller H.

Hum Hered. 2013;76(2):64-75. doi: 10.1159/000357567. Epub 2014 Jan 14.

16.

Comparison of three summary statistics for ranking genes in genome-wide association studies.

Freytag S, Bickeböller H.

Stat Med. 2014 May 20;33(11):1828-41. doi: 10.1002/sim.6063. Epub 2013 Dec 9.

PMID:
24323702
17.

Odor naming and interpretation performance in 881 schizophrenia subjects: association with clinical parameters.

Kästner A, Malzahn D, Begemann M, Hilmes C, Bickeböller H, Ehrenreich H.

BMC Psychiatry. 2013 Aug 30;13:218. doi: 10.1186/1471-244X-13-218.

18.

Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL.

Sohns M, Viktorova E, Amos CI, Brennan P, Fehringer G, Gaborieau V, Han Y, Heinrich J, Chang-Claude J, Hung RJ, Müller-Nurasyid M, Risch A, Lewinger JP, Thomas DC, Bickeböller H.

Genet Epidemiol. 2013 Sep;37(6):551-9. doi: 10.1002/gepi.21741. Epub 2013 Jul 26.

19.

A novel kernel for correcting size bias in the logistic kernel machine test with an application to rheumatoid arthritis.

Freytag S, Bickeböller H, Amos CI, Kneib T, Schlather M.

Hum Hered. 2012;74(2):97-108. doi: 10.1159/000347188. Epub 2013 Mar 1.

20.

Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls.

Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, Goodman G, Heinrich J, Bickeböller H, Rosenberger A, Risch A, Muley T, McLaughlin JR, Benhamou S, Bouchardy C, Lewinger JP, Witte JS, Chen G, Bull S, Hung RJ.

Hum Genet. 2013 May;132(5):579-89. doi: 10.1007/s00439-013-1270-y. Epub 2013 Feb 1.

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