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Results: 1 to 20 of 32

1.

Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions.

Betts MJ, Lu Q, Jiang Y, Drusko A, Wichmann O, Utz M, Valtierra-Gutiérrez IA, Schlesner M, Jaeger N, Jones DT, Pfister S, Lichter P, Eils R, Siebert R, Bork P, Apic G, Gavin AC, Russell RB.

Nucleic Acids Res. 2015 Jan;43(2):e10. doi: 10.1093/nar/gku1094. Epub 2014 Nov 11.

2.

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

Suratanee A, Schaefer MH, Betts MJ, Soons Z, Mannsperger H, Harder N, Oswald M, Gipp M, Ramminger E, Marcus G, Männer R, Rohr K, Wanker E, Russell RB, Andrade-Navarro MA, Eils R, König R.

PLoS Comput Biol. 2014 Sep 25;10(9):e1003814. doi: 10.1371/journal.pcbi.1003814. eCollection 2014 Sep.

3.

SMARCA4-mutated atypical teratoid/rhabdoid tumors are associated with inherited germline alterations and poor prognosis.

Hasselblatt M, Nagel I, Oyen F, Bartelheim K, Russell RB, Schüller U, Junckerstorff R, Rosenblum M, Alassiri AH, Rossi S, Schmid I, Gottardo NG, Toledano H, Viscardi E, Balbin M, Witkowski L, Lu Q, Betts MJ, Foulkes WD, Siebert R, Frühwald MC, Schneppenheim R.

Acta Neuropathol. 2014 Sep;128(3):453-6. doi: 10.1007/s00401-014-1323-x. Epub 2014 Jul 25. No abstract available.

PMID:
25060813
4.

Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols.

Rohde M, Richter J, Schlesner M, Betts MJ, Claviez A, Bonn BR, Zimmermann M, Damm-Welk C, Russell RB, Borkhardt A, Eils R, Hoell JI, Szczepanowski M, Oschlies I, Klapper W, Burkhardt B, Siebert R; German ICGC MMML-Seq-Project; NHL-BFM Study Group.

Genes Chromosomes Cancer. 2014 Nov;53(11):911-6. doi: 10.1002/gcc.22202. Epub 2014 Jul 8.

PMID:
25044415
5.

Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia.

Bergmann AK, Schneppenheim S, Seifert M, Betts MJ, Haake A, Lopez C, Maria Murga Penas E, Vater I, Jayne S, Dyer MJ, Schrappe M, Dührsen U, Ammerpohl O, Russell RB, Küppers R, Dürig J, Siebert R.

Genes Chromosomes Cancer. 2014 Apr;53(4):309-16. doi: 10.1002/gcc.22141. Epub 2014 Jan 21.

PMID:
24446122
6.

Negative protein-protein interaction datasets derived from large-scale two-hybrid experiments.

Trabuco LG, Betts MJ, Russell RB.

Methods. 2012 Dec;58(4):343-8. doi: 10.1016/j.ymeth.2012.07.028. Epub 2012 Aug 4.

PMID:
22884951
7.

Dissecting the genomic complexity underlying medulloblastoma.

Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber UD, Wang Q, Lasitschka B, Bartholomae CC, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts MJ, Russell RB, Coco S, Tonini GP, Schüller U, Hans V, Graf N, Kim YJ, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, von Deimling A, Witt O, Maass E, Rössler J, Ebinger M, Schuhmann MU, Frühwald MC, Hasselblatt M, Jabado N, Rutkowski S, von Bueren AO, Williamson D, Clifford SC, McCabe MG, Collins VP, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott PA, Taylor MD, Meyerson M, Pomeroy SL, Yaspo ML, Korbel JO, Korshunov A, Eils R, Pfister SM, Lichter P.

Nature. 2012 Aug 2;488(7409):100-5. doi: 10.1038/nature11284.

8.

Allosteric modulation of the group III mGlu4 receptor provides functional neuroprotection in the 6-hydroxydopamine rat model of Parkinson's disease.

Betts MJ, O'Neill MJ, Duty S.

Br J Pharmacol. 2012 Aug;166(8):2317-30. doi: 10.1111/j.1476-5381.2012.01943.x.

9.

Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.

van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.

Mol Syst Biol. 2012 Feb 28;8:571. doi: 10.1038/msb.2012.4.

10.

Content disputes in Wikipedia reflect geopolitical instability.

Apic G, Betts MJ, Russell RB.

PLoS One. 2011;6(6):e20902. doi: 10.1371/journal.pone.0020902. Epub 2011 Jun 22.

11.

Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata.

Broadstock M, Austin PJ, Betts MJ, Duty S.

Br J Pharmacol. 2012 Feb;165(4b):1034-45. doi: 10.1111/j.1476-5381.2011.01515.x.

12.

A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae.

Gallego O, Betts MJ, Gvozdenovic-Jeremic J, Maeda K, Matetzki C, Aguilar-Gurrieri C, Beltran-Alvarez P, Bonn S, Fernández-Tornero C, Jensen LJ, Kuhn M, Trott J, Rybin V, Müller CW, Bork P, Kaksonen M, Russell RB, Gavin AC.

Mol Syst Biol. 2010 Nov 30;6:430. doi: 10.1038/msb.2010.87.

13.

Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease.

Austin PJ, Betts MJ, Broadstock M, O'Neill MJ, Mitchell SN, Duty S.

Br J Pharmacol. 2010 Aug;160(7):1741-53. doi: 10.1111/j.1476-5381.2010.00820.x.

14.

The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation.

Arnesen T, Starheim KK, Van Damme P, Evjenth R, Dinh H, Betts MJ, Ryningen A, Vandekerckhove J, Gevaert K, Anderson D.

Mol Cell Biol. 2010 Apr;30(8):1898-909. doi: 10.1128/MCB.01199-09. Epub 2010 Feb 12.

15.

Proteome organization in a genome-reduced bacterium.

Kühner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castaño-Diez D, Chen WH, Devos D, Güell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Böttcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC.

Science. 2009 Nov 27;326(5957):1235-40. doi: 10.1126/science.1176343.

16.

A more structured metabolome.

Betts MJ, Russell RB.

Nat Struct Mol Biol. 2009 Nov;16(11):1125-6. doi: 10.1038/nsmb1109-1125. No abstract available.

PMID:
19888310
17.

A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1).

Arnesen T, Gromyko D, Kagabo D, Betts MJ, Starheim KK, Varhaug JE, Anderson D, Lillehaug JR.

BMC Biochem. 2009 May 29;10:15. doi: 10.1186/1471-2091-10-15.

18.

The molecular architecture of cadherins in native epidermal desmosomes.

Al-Amoudi A, Díez DC, Betts MJ, Frangakis AS.

Nature. 2007 Dec 6;450(7171):832-7.

PMID:
18064004
19.

The hard cell: from proteomics to a whole cell model.

Betts MJ, Russell RB.

FEBS Lett. 2007 Jun 19;581(15):2870-6. Epub 2007 May 30. Review.

20.

Differential localization of coatomer complex isoforms within the Golgi apparatus.

Moelleken J, Malsam J, Betts MJ, Movafeghi A, Reckmann I, Meissner I, Hellwig A, Russell RB, Söllner T, Brügger B, Wieland FT.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4425-30. Epub 2007 Mar 7.

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