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Results: 1 to 20 of 97

1.

Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2.

Fortin J, Boehm U, Deng CX, Treier M, Bernard DJ.

FASEB J. 2014 Apr 16. [Epub ahead of print]

PMID:
24739304
[PubMed - as supplied by publisher]
2.

Bone morphogenetic protein 2 stimulates noncanonical SMAD2/3 signaling via the BMP type 1A receptor in gonadotrope-like cells: implications for FSH synthesis.

Wang Y, Ho CC, Bang E, Rejon CA, Libasci V, Pertchenko P, Hébert TE, Bernard DJ.

Endocrinology. 2014 May;155(5):1970-81. doi: 10.1210/en.2013-1741. Epub 2014 Mar 6.

PMID:
24601881
[PubMed - indexed for MEDLINE]
3.

Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells.

Fortin J, Boehm U, Weinstein MB, Graff JM, Bernard DJ.

FASEB J. 2014 Mar;28(3):1474-85. doi: 10.1096/fj.13-237818. Epub 2013 Dec 5.

PMID:
24308975
[PubMed - indexed for MEDLINE]
4.

The IGSF1 deficiency syndrome: characteristics of male and female patients.

Joustra SD, Schoenmakers N, Persani L, Campi I, Bonomi M, Radetti G, Beck-Peccoz P, Zhu H, Davis TM, Sun Y, Corssmit EP, Appelman-Dijkstra NM, Heinen CA, Pereira AM, Varewijck AJ, Janssen JA, Endert E, Hennekam RC, Lombardi MP, Mannens MM, Bak B, Bernard DJ, Breuning MH, Chatterjee K, Dattani MT, Oostdijk W, Biermasz NR, Wit JM, van Trotsenburg AS.

J Clin Endocrinol Metab. 2013 Dec;98(12):4942-52. doi: 10.1210/jc.2013-2743. Epub 2013 Oct 9.

PMID:
24108313
[PubMed - indexed for MEDLINE]
5.

The CpG island in the murine foxl2 proximal promoter is differentially methylated in primary and immortalized cells.

Tran S, Wang Y, Lamba P, Zhou X, Boehm U, Bernard DJ.

PLoS One. 2013 Oct 2;8(10):e76642. doi: 10.1371/journal.pone.0076642. eCollection 2013.

PMID:
24098544
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells.

Rejon CA, Hancock MA, Li YN, Thompson TB, Hébert TE, Bernard DJ.

Cell Signal. 2013 Dec;25(12):2717-26. doi: 10.1016/j.cellsig.2013.09.002. Epub 2013 Sep 7.

PMID:
24018044
[PubMed - in process]
7.

Three novel IGSF1 mutations in four Japanese patients with X-linked congenital central hypothyroidism.

Nakamura A, Bak B, Silander TL, Lam J, Hotsubo T, Yorifuji T, Ishizu K, Bernard DJ, Tajima T.

J Clin Endocrinol Metab. 2013 Oct;98(10):E1682-91. doi: 10.1210/jc.2013-1224. Epub 2013 Aug 21.

PMID:
23966245
[PubMed - indexed for MEDLINE]
8.

Photoperiod-dependent regulation of gonadotropin-releasing hormone 1 messenger ribonucleic acid levels in the songbird brain.

Stevenson TJ, Bernard DJ, McCarthy MM, Ball GF.

Gen Comp Endocrinol. 2013 Sep 1;190:81-7. doi: 10.1016/j.ygcen.2013.04.011. Epub 2013 May 7. Review.

PMID:
23660447
[PubMed - indexed for MEDLINE]
9.

NR5A2 regulates Lhb and Fshb transcription in gonadotrope-like cells in vitro, but is dispensable for gonadotropin synthesis and fertility in vivo.

Fortin J, Kumar V, Zhou X, Wang Y, Auwerx J, Schoonjans K, Boehm U, Boerboom D, Bernard DJ.

PLoS One. 2013;8(3):e59058. doi: 10.1371/journal.pone.0059058. Epub 2013 Mar 11.

PMID:
23536856
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Cycloheximide inhibits follicle-stimulating hormone β subunit transcription by blocking de novo synthesis of the labile activin type II receptor in gonadotrope cells.

Rejon CA, Ho CC, Wang Y, Zhou X, Bernard DJ, Hébert TE.

Cell Signal. 2013 Jun;25(6):1403-12. doi: 10.1016/j.cellsig.2013.03.002. Epub 2013 Mar 14.

PMID:
23499904
[PubMed - indexed for MEDLINE]
11.

Mechanisms of activin-stimulated FSH synthesis: the story of a pig and a FOX.

Bernard DJ, Tran S.

Biol Reprod. 2013 Mar 28;88(3):78. doi: 10.1095/biolreprod.113.107797. Print 2013 Mar. Review.

PMID:
23426431
[PubMed - indexed for MEDLINE]
Free Article
12.

Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice.

Tran S, Zhou X, Lafleur C, Calderon MJ, Ellsworth BS, Kimmins S, Boehm U, Treier M, Boerboom D, Bernard DJ.

Mol Endocrinol. 2013 Mar;27(3):407-21. doi: 10.1210/me.2012-1286. Epub 2013 Jan 22.

PMID:
23340250
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

IGSF1 deficiency syndrome: A newly uncovered endocrinopathy.

Joustra SD, van Trotsenburg AS, Sun Y, Losekoot M, Bernard DJ, Biermasz NR, Oostdijk W, Wit JM.

Rare Dis. 2013 May 2;1:e24883. doi: 10.4161/rdis.24883. eCollection 2013.

PMID:
25002994
[PubMed]
Free PMC Article
14.

Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement.

Sun Y, Bak B, Schoenmakers N, van Trotsenburg AS, Oostdijk W, Voshol P, Cambridge E, White JK, le Tissier P, Gharavy SN, Martinez-Barbera JP, Stokvis-Brantsma WH, Vulsma T, Kempers MJ, Persani L, Campi I, Bonomi M, Beck-Peccoz P, Zhu H, Davis TM, Hokken-Koelega AC, Del Blanco DG, Rangasami JJ, Ruivenkamp CA, Laros JF, Kriek M, Kant SG, Bosch CA, Biermasz NR, Appelman-Dijkstra NM, Corssmit EP, Hovens GC, Pereira AM, den Dunnen JT, Wade MG, Breuning MH, Hennekam RC, Chatterjee K, Dattani MT, Wit JM, Bernard DJ.

Nat Genet. 2012 Dec;44(12):1375-81. doi: 10.1038/ng.2453. Epub 2012 Nov 11.

PMID:
23143598
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Activin A induction of murine and ovine follicle-stimulating hormone β transcription is SMAD-dependent and TAK1 (MAP3K7)/p38 MAPK-independent in gonadotrope-like cells.

Wang Y, Bernard DJ.

Cell Signal. 2012 Aug;24(8):1632-40. doi: 10.1016/j.cellsig.2012.04.006. Epub 2012 Apr 20.

PMID:
22549017
[PubMed - indexed for MEDLINE]
16.

Disruption of the folate pathway in zebrafish causes developmental defects.

Lee MS, Bonner JR, Bernard DJ, Sanchez EL, Sause ET, Prentice RR, Burgess SM, Brody LC.

BMC Dev Biol. 2012 Apr 5;12:12. doi: 10.1186/1471-213X-12-12.

PMID:
22480165
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

SMADs and FOXL2 synergistically regulate murine FSHbeta transcription via a conserved proximal promoter element.

Tran S, Lamba P, Wang Y, Bernard DJ.

Mol Endocrinol. 2011 Jul;25(7):1170-83. doi: 10.1210/me.2010-0480. Epub 2011 May 26.

PMID:
21622537
[PubMed - indexed for MEDLINE]
18.

Mechanisms of bone morphogenetic protein 2 (BMP2) stimulated inhibitor of DNA binding 3 (Id3) transcription.

Ho CC, Zhou X, Mishina Y, Bernard DJ.

Mol Cell Endocrinol. 2011 Jan 30;332(1-2):242-52. doi: 10.1016/j.mce.2010.10.019. Epub 2010 Nov 4.

PMID:
21056086
[PubMed - indexed for MEDLINE]
19.

Activin A regulates porcine follicle-stimulating hormone beta-subunit transcription via cooperative actions of SMADs and FOXL2.

Lamba P, Wang Y, Tran S, Ouspenskaia T, Libasci V, Hébert TE, Miller GJ, Bernard DJ.

Endocrinology. 2010 Nov;151(11):5456-67. doi: 10.1210/en.2010-0605. Epub 2010 Sep 1.

PMID:
20810560
[PubMed - indexed for MEDLINE]
20.

Bone morphogenetic protein 2 acts via inhibitor of DNA binding proteins to synergistically regulate follicle-stimulating hormone beta transcription with activin A.

Ho CC, Bernard DJ.

Endocrinology. 2010 Jul;151(7):3445-53. doi: 10.1210/en.2010-0071. Epub 2010 May 12.

PMID:
20463050
[PubMed - indexed for MEDLINE]

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