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Items: 1 to 20 of 148


Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8.

Bergeron P, Koehler MF, Blackwood EM, Bowman K, Clark K, Firestein R, Kiefer JR, Maskos K, McCleland ML, Orren L, Ramaswamy S, Salphati L, Schmidt S, Schneider EV, Wu J, Beresini M.

ACS Med Chem Lett. 2016 Apr 5;7(6):595-600. doi: 10.1021/acsmedchemlett.6b00044. eCollection 2016 Jun 9.


Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.

Koehler MF, Bergeron P, Blackwood EM, Bowman K, Clark KR, Firestein R, Kiefer JR, Maskos K, McCleland ML, Orren L, Salphati L, Schmidt S, Schneider EV, Wu J, Beresini MH.

ACS Med Chem Lett. 2016 Jan 6;7(3):223-8. doi: 10.1021/acsmedchemlett.5b00278. eCollection 2016 Mar 10.


Association between Floods and Acute Cardiovascular Diseases: A Population-Based Cohort Study Using a Geographic Information System Approach.

Vanasse A, Cohen A, Courteau J, Bergeron P, Dault R, Gosselin P, Blais C, Bélanger D, Rochette L, Chebana F.

Int J Environ Res Public Health. 2016 Jan 28;13(2):168. doi: 10.3390/ijerph13020168.


Extensive Surgical Treatment of Primary Pulmonary Synovial Sarcoma After Recurrent Pneumothorax.

Petrosyan A, Bergeron P.

Ann Thorac Surg. 2015 Nov;100(5):1893-5. doi: 10.1016/j.athoracsur.2014.12.092.


Homeostatic dysregulation proceeds in parallel in multiple physiological systems.

Li Q, Wang S, Milot E, Bergeron P, Ferrucci L, Fried LP, Cohen AA.

Aging Cell. 2015 Dec;14(6):1103-12. doi: 10.1111/acel.12402. Epub 2015 Sep 29.


Intralocus sexual conflict, adaptive sex allocation, and the heritability of fitness.

Calsbeek R, Duryea MC, Goedert D, Bergeron P, Cox RM.

J Evol Biol. 2015 Nov;28(11):1975-85. doi: 10.1111/jeb.12713. Epub 2015 Aug 27.


An integrated suite of modeling tools that empower scientists in structure- and property-based drug design.

Feng JA, Aliagas I, Bergeron P, Blaney JM, Bradley EK, Koehler MF, Lee ML, Ortwine DF, Tsui V, Wu J, Gobbi A.

J Comput Aided Mol Des. 2015 Jun;29(6):511-23. doi: 10.1007/s10822-015-9845-4. Epub 2015 Apr 29.


Neighbourhood immigration, health care utilization and outcomes in patients with diabetes living in the Montreal metropolitan area (Canada): a population health perspective.

Vanasse A, Courteau J, Orzanco MG, Bergeron P, Cohen AA, Niyonsenga T.

BMC Health Serv Res. 2015 Apr 9;15:146. doi: 10.1186/s12913-015-0824-1.


Direct percutaneous carotid access for carotid angioplasty and stenting.

Bergeron P.

J Endovasc Ther. 2015 Feb;22(1):135-8. doi: 10.1177/1526602814564362.


Detection of a novel, integrative aging process suggests complex physiological integration.

Cohen AA, Milot E, Li Q, Bergeron P, Poirier R, Dusseault-Bélanger F, Fülöp T, Leroux M, Legault V, Metter EJ, Fried LP, Ferrucci L.

PLoS One. 2015 Mar 11;10(3):e0116489. doi: 10.1371/journal.pone.0116489. eCollection 2015.


Chronicling changes to the chronic disease prevention landscape in Canada's public health system 2004-2010.

Hanusaik N, Contandriopoulos D, Kishchuk N, Maximova K, Paradis G, O'Loughlin JL; PHORCAST Decision-makers Advisory Committee.

Public Health. 2014 Aug;128(8):716-24. doi: 10.1016/j.puhe.2014.05.016. Epub 2014 Aug 15.


Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL.

Koehler MF, Bergeron P, Choo EF, Lau K, Ndubaku C, Dudley D, Gibbons P, Sleebs BE, Rye CS, Nikolakopoulos G, Bui C, Kulasegaram S, Kersten WJ, Smith BJ, Czabotar PE, Colman PM, Huang DC, Baell JB, Watson KG, Hasvold L, Tao ZF, Wang L, Souers AJ, Elmore SW, Flygare JA, Fairbrother WJ, Lessene G.

ACS Med Chem Lett. 2014 Mar 21;5(6):662-7. doi: 10.1021/ml500030p. eCollection 2014 Jun 12.


Methodological issues in analyzing small populations using CCHS cycles based on the official language minority studies.

Makvandi E, Bouchard L, Bergeron PJ, Sedigh G.

Can J Public Health. 2013 Jun 13;104(6 Suppl 1):S55-9.


Pulsed resources and the coupling between life-history strategies and exploration patterns in eastern chipmunks (Tamias striatus).

Montiglio PO, Garant D, Bergeron P, Messier GD, Réale D.

J Anim Ecol. 2014 May;83(3):720-8. doi: 10.1111/1365-2656.12174. Epub 2014 Jan 6.


Status update and interim results from the asymptomatic carotid surgery trial-2 (ACST-2).

ACST-2 Collaborative Group, Halliday A, Bulbulia R, Gray W, Naughten A, den Hartog A, Delmestri A, Wallis C, le Conte S, Macdonald S.

Eur J Vasc Endovasc Surg. 2013 Nov;46(5):510-8. doi: 10.1016/j.ejvs.2013.07.020. Epub 2013 Sep 17.


A hit to lead discovery of novel N-methylated imidazolo-, pyrrolo-, and pyrazolo-pyrimidines as potent and selective mTOR inhibitors.

Lee W, Ortwine DF, Bergeron P, Lau K, Lin L, Malek S, Nonomiya J, Pei Z, Robarge KD, Schmidt S, Sideris S, Lyssikatos JP.

Bioorg Med Chem Lett. 2013 Sep 15;23(18):5097-104. doi: 10.1016/j.bmcl.2013.07.027. Epub 2013 Jul 23.


Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2.

Zak M, Hurley CA, Ward SI, Bergeron P, Barrett K, Balazs M, Blair WS, Bull R, Chakravarty P, Chang C, Crackett P, Deshmukh G, DeVoss J, Dragovich PS, Eigenbrot C, Ellwood C, Gaines S, Ghilardi N, Gibbons P, Gradl S, Gribling P, Hamman C, Harstad E, Hewitt P, Johnson A, Johnson T, Kenny JR, Koehler MF, Bir Kohli P, Labadie S, Lee WP, Liao J, Liimatta M, Mendonca R, Narukulla R, Pulk R, Reeve A, Savage S, Shia S, Steffek M, Ubhayakar S, van Abbema A, Aliagas I, Avitabile-Woo B, Xiao Y, Yang J, Kulagowski JJ.

J Med Chem. 2013 Jun 13;56(11):4764-85. doi: 10.1021/jm4004895. Epub 2013 May 31.


Comment on "Bateman in nature: predation on offspring reduces the potential for sexual selection".

Bergeron P, Martin AM, Garant D, Pelletier F.

Science. 2013 May 3;340(6132):549. doi: 10.1126/science.1233246.


Disruptive viability selection on adult exploratory behaviour in eastern chipmunks.

Bergeron P, Montiglio PO, Réale D, Humphries MM, Gimenez O, Garant D.

J Evol Biol. 2013 Apr;26(4):766-74. doi: 10.1111/jeb.12081. Epub 2013 Feb 25.

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