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Page 1
9-[(Furan-2-ylmeth-yl)amino]-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one.
Luo G, Chen H, Zhou J, Tian DL, Zhang S. Luo G, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2087. doi: 10.1107/S1600536811027735. Epub 2011 Jul 23. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 22091107 Free PMC article.
In title compound, C(27)H(27)NO(8), the dihydrofuran-2(3H)-one ring and the six-membered ring fused to it both display envelope conformations. The dihedral angle between the benzene ring of the benzo[d][1,3]dioxole group and the other benzene ring is 60.59 (2). In the crys …
In title compound, C(27)H(27)NO(8), the dihydrofuran-2(3H)-one ring and the six-membered ring fused to it both display envelope conformation …
9-{[4-(Dimethyl-amino)-benz-yl]amino}-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one.
Li Y, Wang H, Chen H, Chen LT, Liu J. Li Y, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1538-9. doi: 10.1107/S1600536811019234. Epub 2011 May 28. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 21754898 Free PMC article.
In the title compound, C(31)H(34)N(2)O(7), the fused tetra-hydro-furan and six-membered rings each display an envelope conformation. The dihedral angles between the benzene ring of the benzo[d][1,3]dioxole and the other two benzene rings are 89.68 (3) and 63.38 (2). …
In the title compound, C(31)H(34)N(2)O(7), the fused tetra-hydro-furan and six-membered rings each display an envelope conformation. …
9-[(2-Meth-oxy-benz-yl)amino]-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one.
Shi S, Tian D, Luo G, Ai T, Chen H. Shi S, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2045. doi: 10.1107/S160053681202572X. Epub 2012 Jun 13. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22807870 Free PMC article.
In the title compound, C(30)H(31)NO(8), the tetra-hydro-furan ring and the six-membered ring fused to it both display envelope conformations, both having the same C atom as the flap. The dihedral angles between the benzene ring of the benzo[d][1,3]dioxole ring syste …
In the title compound, C(30)H(31)NO(8), the tetra-hydro-furan ring and the six-membered ring fused to it both display envelope confor …
9-[(2-Chloro-benz-yl)amino]-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one.
Zhu TL, Jin JR, Chen H, Chen LT, Liu J. Zhu TL, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1491. doi: 10.1107/S1600536811018289. Epub 2011 May 25. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 21754859 Free PMC article.
In the title compound, C(29)H(28)ClNO(7), the tetra-hydro-furan ring and the six-membered ring fused to it both display envelope conformations. The dihedral angles between the plane of the benzene ring of the benzo[d][1,3]dioxole system and the planes of the other t …
In the title compound, C(29)H(28)ClNO(7), the tetra-hydro-furan ring and the six-membered ring fused to it both display envelope conf …
Copper(i)-Y zeolite catalyzed N-sulfonylketenimine mediated annulation of hydroxynaphthoquinones: syntheses of naphtho[2,1-b]furan-2,5-diones and benzo[de]chromene-2,6-diones.
Ramanathan D, Namitharan K, Pitchumani K. Ramanathan D, et al. Chem Commun (Camb). 2016 Jun 28;52(54):8436-9. doi: 10.1039/c6cc03571j. Chem Commun (Camb). 2016. PMID: 27305854
An efficient one pot synthesis for the construction of novel naphtho[2,1-b]furan-2,5-diones and benzo[de]chromene-2,6-diones using copper(i)-Y zeolite catalyzed reaction of N-sulfonylketenimine with 2-hydroxy-1,4-naphthoquinone and 5-hydroxy-1,4-naphthoquinon …
An efficient one pot synthesis for the construction of novel naphtho[2,1-b]furan-2,5-diones and benzo[de]chromene-2,6-d …
Anticancer properties of new synthetic hybrid molecules combining naphtho[2,3-b]furan-4,9-dione or benzo[f]indole-4,9-dione motif with phosphonate subunit.
Gach K, Modranka J, Szymański J, Pomorska D, Krajewska U, Mirowski M, Janecki T, Janecka A. Gach K, et al. Eur J Med Chem. 2016 Sep 14;120:51-63. doi: 10.1016/j.ejmech.2016.05.002. Epub 2016 May 3. Eur J Med Chem. 2016. PMID: 27187858
In this paper we report an efficient and general synthesis of substituted 3-diethoxyphosphorylnaphtho [2,3-b]furan-4,9-diones and 3-diethoxyphosphorylbenzo [f]indole-4,9-diones which integrate the natural 1,4-naphtalenedione scaffold, present in several anticancer agents w …
In this paper we report an efficient and general synthesis of substituted 3-diethoxyphosphorylnaphtho [2,3-b]furan-4,9-diones and 3-d …
Divergent Transformations of 2-Nitro-1H-benzo[f]chromenes in Reactions with Alkylidenemalononitriles: Access to Naphtho[2,1-b]furans via Base-Mediated Pyran Ring Contraction.
Korzhenko KS, Yushkova AS, Osipov DV, Rashchepkina DA, Demidov OP, Osyanin VA. Korzhenko KS, et al. Org Lett. 2024 Feb 23;26(7):1310-1315. doi: 10.1021/acs.orglett.3c03879. Epub 2024 Feb 8. Org Lett. 2024. PMID: 38329453
The action of 2-(1-arylethylidene)malononitriles on 2-nitro-1H-benzo[f]chromenes in the presence of Et(3)N and MoO(3).2H(2)O results in naphtho[2,1-b]furans containing an allylidenemalononitrile unit in the alpha-position. ...The possibility of further transformatio …
The action of 2-(1-arylethylidene)malononitriles on 2-nitro-1H-benzo[f]chromenes in the presence of Et(3)N and MoO(3).2H(2)O results …
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives.
Cheng CC, Dong Q, Liu DF, Luo YL, Liu LF, Chen AY, Yu C, Savaraj N, Chou TC. Cheng CC, et al. J Med Chem. 1993 Dec 10;36(25):4108-12. doi: 10.1021/jm00077a016. J Med Chem. 1993. PMID: 8258835
Based on the "2-phenylnaphthalene-type" structural pattern hypothesis developed in our laboratory, a number of benzo[b]naphtho[2,3-d]furan-6,11-diones were designed, synthesized, and evaluated in vitro for their inhibitory action against the growth of human p …
Based on the "2-phenylnaphthalene-type" structural pattern hypothesis developed in our laboratory, a number of benzo[b]naphtho
21 results