Anticancer properties of new synthetic hybrid molecules combining naphtho[2,3-b]furan-4,9-dione or benzo[f]indole-4,9-dione motif with phosphonate subunit.
Gach K, Modranka J, Szymański J, Pomorska D, Krajewska U, Mirowski M, Janecki T, Janecka A.
Gach K, et al.
Eur J Med Chem. 2016 Sep 14;120:51-63. doi: 10.1016/j.ejmech.2016.05.002. Epub 2016 May 3.
Eur J Med Chem. 2016.
PMID: 27187858
In this paper we report an efficient and general synthesis of substituted 3-diethoxyphosphorylnaphtho [2,3-b]furan-4,9-diones and 3-diethoxyphosphorylbenzo [f]indole-4,9-diones which integrate the natural 1,4-naphtalenedione scaffold, present in several anticancer agents w …
In this paper we report an efficient and general synthesis of substituted 3-diethoxyphosphorylnaphtho [2,3-b]furan-4,9-diones and 3-d …