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Results: 1 to 20 of 64

1.

CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases.

Leroy C, Shen Q, Strande V, Meyer R, McLaughlin ME, Lezan E, Bentires-Alj M, Voshol H, Bonenfant D, Alex Gaither L.

Oncogene. 2015 Mar 2. doi: 10.1038/onc.2015.19. [Epub ahead of print]

PMID:
25728678
2.

Breast cancer prevention: lessons to be learned from mechanisms of early pregnancy-mediated breast cancer protection.

Meier-Abt F, Bentires-Alj M, Rochlitz C.

Cancer Res. 2015 Mar 1;75(5):803-7. doi: 10.1158/0008-5472.CAN-14-2717. Epub 2015 Feb 6.

PMID:
25660950
3.

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.

Bonapace L, Coissieux MM, Wyckoff J, Mertz KD, Varga Z, Junt T, Bentires-Alj M.

Nature. 2014 Nov 6;515(7525):130-3. doi: 10.1038/nature13862. Epub 2014 Oct 22.

PMID:
25337873
4.

Mechanism-based cancer therapy: resistance to therapy, therapy for resistance.

Ramos P, Bentires-Alj M.

Oncogene. 2014 Sep 29. doi: 10.1038/onc.2014.314. [Epub ahead of print] Review.

PMID:
25263438
5.

Anticipating mechanisms of resistance to PI3K inhibition in breast cancer: a challenge in the era of precision medicine.

Leroy C, Amante RJ, Bentires-Alj M.

Biochem Soc Trans. 2014 Aug;42(4):733-41. doi: 10.1042/BST20140034. Review.

PMID:
25109950
6.
7.

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases.

Sausgruber N, Coissieux MM, Britschgi A, Wyckoff J, Aceto N, Leroy C, Stadler MB, Voshol H, Bonenfant D, Bentires-Alj M.

Oncogene. 2015 Apr 23;34(17):2272-8. doi: 10.1038/onc.2014.170. Epub 2014 Jun 16.

PMID:
24931162
8.

Memo is a copper-dependent redox protein with an essential role in migration and metastasis.

MacDonald G, Nalvarte I, Smirnova T, Vecchi M, Aceto N, Dolemeyer A, Frei A, Lienhard S, Wyckoff J, Hess D, Seebacher J, Keusch JJ, Gut H, Salaun D, Mazzarol G, Disalvatore D, Bentires-Alj M, Di Fiore PP, Badache A, Hynes NE.

Sci Signal. 2014 Jun 10;7(329):ra56. doi: 10.1126/scisignal.2004870.

PMID:
24917593
9.

Mesenchymal precursor cells maintain the differentiation and proliferation potentials of breast epithelial cells.

Duss S, Brinkhaus H, Britschgi A, Cabuy E, Frey DM, Schaefer DJ, Bentires-Alj M.

Breast Cancer Res. 2014 Jun 10;16(3):R60. doi: 10.1186/bcr3673.

10.

MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation.

Shostak K, Patrascu F, Göktuna SI, Close P, Borgs L, Nguyen L, Olivier F, Rammal A, Brinkhaus H, Bentires-Alj M, Marine JC, Chariot A.

Cell Death Differ. 2014 May;21(5):811-24. doi: 10.1038/cdd.2014.2. Epub 2014 Jan 31.

11.

VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation.

Fantozzi A, Gruber DC, Pisarsky L, Heck C, Kunita A, Yilmaz M, Meyer-Schaller N, Cornille K, Hopfer U, Bentires-Alj M, Christofori G.

Cancer Res. 2014 Mar 1;74(5):1566-75. doi: 10.1158/0008-5472.CAN-13-1641. Epub 2014 Jan 10.

12.

How pregnancy at early age protects against breast cancer.

Meier-Abt F, Bentires-Alj M.

Trends Mol Med. 2014 Mar;20(3):143-53. doi: 10.1016/j.molmed.2013.11.002. Epub 2013 Dec 16. Review.

PMID:
24355762
13.

Targeting PI3K, HER2 and the IL-8/JAK2 axis in metastatic breast cancer: Which combination makes the whole greater than the sum of its parts?

Britschgi A, Radimerski T, Bentires-Alj M.

Drug Resist Updat. 2013 Jul-Nov;16(3-5):68-72. doi: 10.1016/j.drup.2013.10.001. Epub 2013 Oct 10. Review.

PMID:
24169539
15.

Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R.

Meyer DS, Koren S, Leroy C, Brinkhaus H, Müller U, Klebba I, Müller M, Cardiff RD, Bentires-Alj M.

Oncogenesis. 2013 Sep 30;2:e74. doi: 10.1038/oncsis.2013.38.

16.

Mammary tumor formation and metastasis evoked by a HER2 splice variant.

Alajati A, Sausgruber N, Aceto N, Duss S, Sarret S, Voshol H, Bonenfant D, Bentires-Alj M.

Cancer Res. 2013 Sep 1;73(17):5320-7. doi: 10.1158/0008-5472.CAN-12-3186. Epub 2013 Jul 18.

17.

A tumorigenic actin mutant alters fibroblast morphology and multicellular assembly properties.

Blache U, Silván U, Plodinec M, Suetterlin R, Jakob R, Klebba I, Bentires-Alj M, Aebi U, Schoenenberger CA.

Cytoskeleton (Hoboken). 2013 Oct;70(10):635-50. doi: 10.1002/cm.21120. Epub 2013 Jul 19.

PMID:
23804571
18.

Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium.

Meier-Abt F, Milani E, Roloff T, Brinkhaus H, Duss S, Meyer DS, Klebba I, Balwierz PJ, van Nimwegen E, Bentires-Alj M.

Breast Cancer Res. 2013 Apr 29;15(2):R36. doi: 10.1186/bcr3419.

19.

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.

Britschgi A, Bill A, Brinkhaus H, Rothwell C, Clay I, Duss S, Rebhan M, Raman P, Guy CT, Wetzel K, George E, Popa MO, Lilley S, Choudhury H, Gosling M, Wang L, Fitzgerald S, Borawski J, Baffoe J, Labow M, Gaither LA, Bentires-Alj M.

Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):E1026-34. doi: 10.1073/pnas.1217072110. Epub 2013 Feb 19.

20.

Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors.

Koren S, Bentires-Alj M.

FEBS J. 2013 Jun;280(12):2758-65. doi: 10.1111/febs.12175. Epub 2013 Mar 1. Review.

PMID:
23384338
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