Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 124

1.

Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.

Flynn RL, Cox KE, Jeitany M, Wakimoto H, Bryll AR, Ganem NJ, Bersani F, Pineda JR, Suvà ML, Benes CH, Haber DA, Boussin FD, Zou L.

Science. 2015 Jan 16;347(6219):273-7. doi: 10.1126/science.1257216.

PMID:
25593184
[PubMed - indexed for MEDLINE]
2.

A Coding Single Nucleotide Polymorphism in Lysine Demethylase KDM4A Associates with Increased Sensitivity to mTOR Inhibitors.

Van Rechem C, Black JC, Greninger P, Zhao Y, Donado C, Burrowes PD, Ladd B, Christiani DC, Benes CH, Whetstine JR.

Cancer Discov. 2015 Jan 6. pii: CD-14-1159. [Epub ahead of print]

PMID:
25564517
[PubMed - as supplied by publisher]
3.

Lysine Demethylase KDM4A Associates with Translation Machinery and Regulates Protein Synthesis.

Van Rechem C, Black JC, Boukhali M, Aryee MJ, Graslund S, Haas W, Benes CH, Whetstine JR.

Cancer Discov. 2015 Jan 6. pii: CD-14-1326. [Epub ahead of print]

PMID:
25564516
[PubMed - as supplied by publisher]
4.

Measurement of PIP3 Levels Reveals an Unexpected Role for p110β in Early Adaptive Responses to p110α-Specific Inhibitors in Luminal Breast Cancer.

Costa C, Ebi H, Martini M, Beausoleil SA, Faber AC, Jakubik CT, Huang A, Wang Y, Nishtala M, Hall B, Rikova K, Zhao J, Hirsch E, Benes CH, Engelman JA.

Cancer Cell. 2015 Jan 12;27(1):97-108. doi: 10.1016/j.ccell.2014.11.007. Epub 2014 Dec 24.

PMID:
25544637
[PubMed - in process]
5.

[Pertussis trend in children under one year of age in the Czech Republic in 1997-2013].

Fabiánová K, Šebestová H, Beneš Č, Zavadilová J, Křížová P, Kříž B.

Epidemiol Mikrobiol Imunol. 2014 Fall;63(4):270-7. Czech.

PMID:
25523219
[PubMed - in process]
6.

The role of game (wild boar and roe deer) in the spread of tick-borne encephalitis in the Czech Republic.

Kriz B, Daniel M, Benes C, Maly M.

Vector Borne Zoonotic Dis. 2014 Nov;14(11):801-7. doi: 10.1089/vbz.2013.1569.

PMID:
25409271
[PubMed - in process]
Free PMC Article
7.

Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

Crystal AS, Shaw AT, Sequist LV, Friboulet L, Niederst MJ, Lockerman EL, Frias RL, Gainor JF, Amzallag A, Greninger P, Lee D, Kalsy A, Gomez-Caraballo M, Elamine L, Howe E, Hur W, Lifshits E, Robinson HE, Katayama R, Faber AC, Awad MM, Ramaswamy S, Mino-Kenudson M, Iafrate AJ, Benes CH, Engelman JA.

Science. 2014 Dec 19;346(6216):1480-6. doi: 10.1126/science.1254721. Epub 2014 Nov 13.

PMID:
25394791
[PubMed - indexed for MEDLINE]
8.

Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy.

Choy E, Butrynski JE, Harmon DC, Morgan JA, George S, Wagner AJ, D'Adamo D, Cote GM, Flamand Y, Benes CH, Haber DA, Baselga JM, Demetri GD.

BMC Cancer. 2014 Nov 5;14:813. doi: 10.1186/1471-2407-14-813.

PMID:
25374341
[PubMed - in process]
Free PMC Article
9.

Combined MEK and PI3K Inhibition in a Mouse Model of Pancreatic Cancer.

Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Deshpande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes C, Engelman JA, Bardeesy N.

Clin Cancer Res. 2015 Jan 15;21(2):396-404. doi: 10.1158/1078-0432.CCR-14-1591. Epub 2014 Oct 27.

PMID:
25348516
[PubMed - in process]
10.

Drugging MYCN through an allosteric transition in Aurora kinase A.

Gustafson WC, Meyerowitz JG, Nekritz EA, Chen J, Benes C, Charron E, Simonds EF, Seeger R, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA.

Cancer Cell. 2014 Sep 8;26(3):414-27. doi: 10.1016/j.ccr.2014.07.015. Epub 2014 Aug 28.

PMID:
25175806
[PubMed - indexed for MEDLINE]
11.

Peri-urbanisation, counter-urbanisation, and an extension of residential exposure to ticks: a clue to the trends in Lyme borreliosis incidence in the Czech Republic?

Zeman P, Benes C.

Ticks Tick Borne Dis. 2014 Oct;5(6):907-16. doi: 10.1016/j.ttbdis.2014.07.006. Epub 2014 Aug 10.

PMID:
25113985
[PubMed - in process]
12.

Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets.

Duan Q, Wang Z, Fernandez NF, Rouillard AD, Tan CM, Benes CH, Ma'ayan A.

Bioinformatics. 2014 Nov 15;30(22):3289-90. doi: 10.1093/bioinformatics/btu526. Epub 2014 Aug 6.

PMID:
25100688
[PubMed - indexed for MEDLINE]
13.

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.

Kwiatkowski N, Zhang T, Rahl PB, Abraham BJ, Reddy J, Ficarro SB, Dastur A, Amzallag A, Ramaswamy S, Tesar B, Jenkins CE, Hannett NM, McMillin D, Sanda T, Sim T, Kim ND, Look T, Mitsiades CS, Weng AP, Brown JR, Benes CH, Marto JA, Young RA, Gray NS.

Nature. 2014 Jul 31;511(7511):616-20. doi: 10.1038/nature13393. Epub 2014 Jun 22.

PMID:
25043025
[PubMed - indexed for MEDLINE]
14.

Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility.

Yu M, Bardia A, Aceto N, Bersani F, Madden MW, Donaldson MC, Desai R, Zhu H, Comaills V, Zheng Z, Wittner BS, Stojanov P, Brachtel E, Sgroi D, Kapur R, Shioda T, Ting DT, Ramaswamy S, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, Haber DA.

Science. 2014 Jul 11;345(6193):216-20. doi: 10.1126/science.1253533.

PMID:
25013076
[PubMed - indexed for MEDLINE]
15.

CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers.

Heilmann AM, Perera RM, Ecker V, Nicolay BN, Bardeesy N, Benes CH, Dyson NJ.

Cancer Res. 2014 Jul 15;74(14):3947-58. doi: 10.1158/0008-5472.CAN-13-2923. Epub 2014 Jul 1.

PMID:
24986516
[PubMed - indexed for MEDLINE]
16.

EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation.

Wang M, Kern AM, Hülskötter M, Greninger P, Singh A, Pan Y, Chowdhury D, Krause M, Baumann M, Benes CH, Efstathiou JA, Settleman J, Willers H.

Cancer Res. 2014 May 15;74(10):2825-34. doi: 10.1158/0008-5472.CAN-13-3157. Epub 2014 Mar 19.

PMID:
24648348
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Metadata Standard and Data Exchange Specifications to Describe, Model, and Integrate Complex and Diverse High-Throughput Screening Data from the Library of Integrated Network-based Cellular Signatures (LINCS).

Vempati UD, Chung C, Mader C, Koleti A, Datar N, Vidović D, Wrobel D, Erickson S, Muhlich JL, Berriz G, Benes CH, Subramanian A, Pillai A, Shamu CE, Schürer SC.

J Biomol Screen. 2014 Feb 11;19(5):803-816. [Epub ahead of print]

PMID:
24518066
[PubMed - as supplied by publisher]
18.

EMT twists the road to PI3K.

Niederst MJ, Benes CH.

Cancer Discov. 2014 Feb;4(2):149-51. doi: 10.1158/2159-8290.CD-13-1030.

PMID:
24501304
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Rotavirus gastroenteritis in the Czech Republic before the start of vaccination.

Pazdiora P, Beneš Č.

Epidemiol Mikrobiol Imunol. 2013 Dec;62(4):131-7.

PMID:
24467174
[PubMed - in process]
20.

PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1.

Ebi H, Costa C, Faber AC, Nishtala M, Kotani H, Juric D, Della Pelle P, Song Y, Yano S, Mino-Kenudson M, Benes CH, Engelman JA.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21124-9. doi: 10.1073/pnas.1314124110. Epub 2013 Dec 10.

PMID:
24327733
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk