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Results: 1 to 20 of 115

1.

Drugging MYCN through an allosteric transition in Aurora kinase A.

Gustafson WC, Meyerowitz JG, Nekritz EA, Chen J, Benes C, Charron E, Simonds EF, Seeger R, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA.

Cancer Cell. 2014 Sep 8;26(3):414-27. doi: 10.1016/j.ccr.2014.07.015. Epub 2014 Aug 28.

PMID:
25175806
[PubMed - in process]
2.

Peri-urbanisation, counter-urbanisation, and an extension of residential exposure to ticks: A clue to the trends in Lyme borreliosis incidence in the Czech Republic?

Zeman P, Benes C.

Ticks Tick Borne Dis. 2014 Oct;5(6):907-16. doi: 10.1016/j.ttbdis.2014.07.006. Epub 2014 Aug 10.

PMID:
25113985
[PubMed - in process]
3.

Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets.

Duan Q, Wang Z, Fernandez NF, Rouillard AD, Tan CM, Benes CH, Ma'ayan A.

Bioinformatics. 2014 Aug 6. pii: btu526. [Epub ahead of print]

PMID:
25100688
[PubMed - as supplied by publisher]
4.

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.

Kwiatkowski N, Zhang T, Rahl PB, Abraham BJ, Reddy J, Ficarro SB, Dastur A, Amzallag A, Ramaswamy S, Tesar B, Jenkins CE, Hannett NM, McMillin D, Sanda T, Sim T, Kim ND, Look T, Mitsiades CS, Weng AP, Brown JR, Benes CH, Marto JA, Young RA, Gray NS.

Nature. 2014 Jul 31;511(7511):616-20. doi: 10.1038/nature13393. Epub 2014 Jun 22.

PMID:
25043025
[PubMed - indexed for MEDLINE]
5.

Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility.

Yu M, Bardia A, Aceto N, Bersani F, Madden MW, Donaldson MC, Desai R, Zhu H, Comaills V, Zheng Z, Wittner BS, Stojanov P, Brachtel E, Sgroi D, Kapur R, Shioda T, Ting DT, Ramaswamy S, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, Haber DA.

Science. 2014 Jul 11;345(6193):216-20. doi: 10.1126/science.1253533.

PMID:
25013076
[PubMed - indexed for MEDLINE]
6.

CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers.

Heilmann AM, Perera RM, Ecker V, Nicolay BN, Bardeesy N, Benes CH, Dyson NJ.

Cancer Res. 2014 Jul 15;74(14):3947-58. doi: 10.1158/0008-5472.CAN-13-2923. Epub 2014 Jul 1.

PMID:
24986516
[PubMed - indexed for MEDLINE]
7.

EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation.

Wang M, Kern AM, Hülskötter M, Greninger P, Singh A, Pan Y, Chowdhury D, Krause M, Baumann M, Benes CH, Efstathiou JA, Settleman J, Willers H.

Cancer Res. 2014 May 15;74(10):2825-34. doi: 10.1158/0008-5472.CAN-13-3157. Epub 2014 Mar 19.

PMID:
24648348
[PubMed - indexed for MEDLINE]
8.

Metadata Standard and Data Exchange Specifications to Describe, Model, and Integrate Complex and Diverse High-Throughput Screening Data from the Library of Integrated Network-based Cellular Signatures (LINCS).

Vempati UD, Chung C, Mader C, Koleti A, Datar N, Vidović D, Wrobel D, Erickson S, Muhlich JL, Berriz G, Benes CH, Subramanian A, Pillai A, Shamu CE, Schürer SC.

J Biomol Screen. 2014 Feb 11;19(5):803-816. [Epub ahead of print]

PMID:
24518066
[PubMed - as supplied by publisher]
9.

EMT twists the road to PI3K.

Niederst MJ, Benes CH.

Cancer Discov. 2014 Feb;4(2):149-51. doi: 10.1158/2159-8290.CD-13-1030.

PMID:
24501304
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Rotavirus gastroenteritis in the Czech Republic before the start of vaccination.

Pazdiora P, Beneš Č.

Epidemiol Mikrobiol Imunol. 2013 Dec;62(4):131-7.

PMID:
24467174
[PubMed - in process]
11.

PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1.

Ebi H, Costa C, Faber AC, Nishtala M, Kotani H, Juric D, Della Pelle P, Song Y, Yano S, Mino-Kenudson M, Benes CH, Engelman JA.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21124-9. doi: 10.1073/pnas.1314124110. Epub 2013 Dec 10.

PMID:
24327733
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.

Faber AC, Coffee EM, Costa C, Dastur A, Ebi H, Hata AN, Yeo AT, Edelman EJ, Song Y, Tam AT, Boisvert JL, Milano RJ, Roper J, Kodack DP, Jain RK, Corcoran RB, Rivera MN, Ramaswamy S, Hung KE, Benes CH, Engelman JA.

Cancer Discov. 2014 Jan;4(1):42-52. doi: 10.1158/2159-8290.CD-13-0315. Epub 2013 Oct 25.

PMID:
24163374
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Spatial distribution of a population at risk: an important factor for understanding the recent rise in tick-borne diseases (Lyme borreliosis and tick-borne encephalitis in the Czech Republic).

Zeman P, Benes C.

Ticks Tick Borne Dis. 2013 Dec;4(6):522-30. doi: 10.1016/j.ttbdis.2013.07.003. Epub 2013 Oct 16.

PMID:
24139627
[PubMed - in process]
14.

Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.

Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT.

J Biol Chem. 2013 Nov 22;288(47):33542-58. doi: 10.1074/jbc.M113.511170. Epub 2013 Oct 2.

PMID:
24089526
[PubMed - indexed for MEDLINE]
15.

EGFR-activating mutations correlate with a Fanconi anemia-like cellular phenotype that includes PARP inhibitor sensitivity.

Pfäffle HN, Wang M, Gheorghiu L, Ferraiolo N, Greninger P, Borgmann K, Settleman J, Benes CH, Sequist LV, Zou L, Willers H.

Cancer Res. 2013 Oct 15;73(20):6254-63. doi: 10.1158/0008-5472.CAN-13-0044. Epub 2013 Aug 21.

PMID:
23966292
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation.

Manning AL, Benes C, Dyson NJ.

Oncogene. 2014 May 8;33(19):2487-94. doi: 10.1038/onc.2013.201. Epub 2013 Jun 24.

PMID:
23792446
[PubMed - indexed for MEDLINE]
17.

Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay.

Tang Y, Xie T, Florian S, Moerke N, Shamu C, Benes C, Mitchison TJ.

J Biomol Screen. 2013 Oct;18(9):1062-71. doi: 10.1177/1087057113493804. Epub 2013 Jun 20.

PMID:
23788527
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

[Differences in the incidence of viral hepatitis A and E in the Czech Republic].

Trmal J, Beneš C, Trnková M.

Epidemiol Mikrobiol Imunol. 2013 Apr;62(1):19-25. Czech.

PMID:
23768091
[PubMed - indexed for MEDLINE]
19.

[Incidence of tick-borne encephalitis in the czech republic in 2001-2011 in different administrative regions and municipalities with extended power].

Kříž B, Beneš C, Daniel M, Malý M.

Epidemiol Mikrobiol Imunol. 2013 Apr;62(1):9-18. Czech.

PMID:
23768090
[PubMed - indexed for MEDLINE]
20.

Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties.

Menden MP, Iorio F, Garnett M, McDermott U, Benes CH, Ballester PJ, Saez-Rodriguez J.

PLoS One. 2013 Apr 30;8(4):e61318. doi: 10.1371/journal.pone.0061318. Print 2013.

PMID:
23646105
[PubMed - indexed for MEDLINE]
Free PMC Article

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