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Results: 20

1.

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium, Todd JA, Wallace C, Concannon P, Rich SS.

Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9.

PMID:
25751624
2.

Antigen-specific inhibition of high-avidity T cell target lysis by low-avidity T cells via trogocytosis.

Chung B, Stuge TB, Murad JP, Beilhack G, Andersen E, Armstrong BD, Weber JS, Lee PP.

Cell Rep. 2014 Aug 7;8(3):871-82. doi: 10.1016/j.celrep.2014.06.052. Epub 2014 Jul 31.

3.

B6.g7 mice reconstituted with BDC2·5 non-obese diabetic (BDC2·5NOD) stem cells do not develop autoimmune diabetes.

Rajasekaran N, Wang N, Hang Y, Macaubas C, Rinderknecht C, Beilhack GF, Shizuru JA, Mellins ED.

Clin Exp Immunol. 2013 Oct;174(1):27-37. doi: 10.1111/cei.12163.

4.

A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model.

Bäuerlein CA, Riedel SS, Baker J, Brede C, Garrote AL, Chopra M, Ritz M, Beilhack GF, Schulz S, Zeiser R, Schlegel PG, Einsele H, Negrin RS, Beilhack A.

BMC Med. 2013 May 21;11:134. doi: 10.1186/1741-7015-11-134.

5.

Host-derived CD4+ T cells attenuate stem cell-mediated transfer of autoimmune arthritis in lethally irradiated C57BL/6.g7 mice.

Rajasekaran N, Wang N, Truong P, Rinderknecht C, Macaubas C, Beilhack GF, Shizuru JA, Mellins ED.

Arthritis Rheum. 2013 Mar;65(3):681-92. doi: 10.1002/art.37800.

6.

Clinical evaluation of two novel biointact PTH(1-84) assays in hemodialysis patients.

Hecking M, Kainz A, Bielesz B, Plischke M, Beilhack G, Hörl WH, Sunder-Plassmann G, Bieglmayer C.

Clin Biochem. 2012 Dec;45(18):1645-51. doi: 10.1016/j.clinbiochem.2012.08.006. Epub 2012 Aug 11.

7.

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.

Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC, Bhaw-Rosun L, Bockett NA, Brand OJ, Brouwer E, Concannon P, Cooper JD, Dias KR, van Diemen CC, Dubois PC, Edkins S, Fölster-Holst R, Fransen K, Glass DN, Heap GA, Hofmann S, Huizinga TW, Hunt S, Langford C, Lee J, Mansfield J, Marrosu MG, Mathew CG, Mein CA, Müller-Quernheim J, Nutland S, Onengut-Gumuscu S, Ouwehand W, Pearce K, Prescott NJ, Posthumus MD, Potter S, Rosati G, Sambrook J, Satsangi J, Schreiber S, Shtir C, Simmonds MJ, Sudman M, Thompson SD, Toes R, Trynka G, Vyse TJ, Walker NM, Weidinger S, Zhernakova A, Zoledziewska M; Type 1 Diabetes Genetics Consortium; UK Inflammatory Bowel Disease (IBD) Genetics Consortium; Wellcome Trust Case Control Consortium, Weersma RK, Gough SC, Sawcer S, Wijmenga C, Parkes M, Cucca F, Franke A, Deloukas P, Rich SS, Todd JA, van Heel DA.

Nat Genet. 2011 Dec 27;44(1):3-5. doi: 10.1038/ng.1037. No abstract available.

8.

Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC).

Hilner JE, Perdue LH, Sides EG, Pierce JJ, Wägner AM, Aldrich A, Loth A, Albret L, Wagenknecht LE, Nierras C, Akolkar B; T1DGC.

Clin Trials. 2010;7(1 Suppl):S5-S32. doi: 10.1177/1740774510373497. Epub 2010 Jul 5.

9.

Human risk allele HLA-DRB1*0405 predisposes class II transgenic Ab0 NOD mice to autoimmune pancreatitis.

Freitag TL, Cham C, Sung HH, Beilhack GF, Durinovic-Belló I, Patel SD, Bronson RT, Schuppan D, Sønderstrup G.

Gastroenterology. 2010 Jul;139(1):281-91. doi: 10.1053/j.gastro.2010.03.038. Epub 2010 Mar 18.

10.

Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice.

Hamilton-Williams EE, Martinez X, Clark J, Howlett S, Hunter KM, Rainbow DB, Wen L, Shlomchik MJ, Katz JD, Beilhack GF, Wicker LS, Sherman LA.

J Immunol. 2009 Aug 1;183(3):1533-41. doi: 10.4049/jimmunol.0900428. Epub 2009 Jul 10.

11.

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium.

Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10.

12.

Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organs.

Beilhack A, Schulz S, Baker J, Beilhack GF, Nishimura R, Baker EM, Landan G, Herman EI, Butcher EC, Contag CH, Negrin RS.

Blood. 2008 Mar 1;111(5):2919-28. Epub 2007 Nov 7.

13.

Alloreactive T-cell trafficking after hematopoietic stem cell transplantation.

Beilhack A, Schulz S, Baker J, Beilhack G, Herman E, Baker E, Landan G, Nishimura R, Butcher E, Contag Ch, Negrin R.

J Stem Cells Regen Med. 2007 May 16;2(1):107. eCollection 2007. No abstract available.

PMID:
24692934
14.

Alloreactive T-cell trafficking after hematopoietic stem cell transplantation.

Beilhack A, Schulz S, Baker J, Beilhack G, Herman E, Baker E, Landan G, Nishimura R, Butcher E, Contag Ch, Negrin R.

J Stem Cells Regen Med. 2007 May 16;2(1):17. eCollection 2007. No abstract available.

PMID:
24692881
15.

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.

Chaparro RJ, Konigshofer Y, Beilhack GF, Shizuru JA, McDevitt HO, Chien YH.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12475-80. Epub 2006 Aug 8. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15273.

16.

The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation.

Lee LF, Xu B, Michie SA, Beilhack GF, Warganich T, Turley S, McDevitt HO.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15995-6000. Epub 2005 Oct 24.

17.
18.

In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets.

Beilhack A, Schulz S, Baker J, Beilhack GF, Wieland CB, Herman EI, Baker EM, Cao YA, Contag CH, Negrin RS.

Blood. 2005 Aug 1;106(3):1113-22. Epub 2005 Apr 26.

19.

Biology of hematopoietic stem cells and progenitors: implications for clinical application.

Kondo M, Wagers AJ, Manz MG, Prohaska SS, Scherer DC, Beilhack GF, Shizuru JA, Weissman IL.

Annu Rev Immunol. 2003;21:759-806. Epub 2002 Dec 17. Review.

PMID:
12615892
20.

Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice.

Beilhack GF, Scheffold YC, Weissman IL, Taylor C, Jerabek L, Burge MJ, Masek MA, Shizuru JA.

Diabetes. 2003 Jan;52(1):59-68.

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