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Association Between NRAS and BRAF Mutational Status and Melanoma-Specific Survival Among Patients With Higher Risk Primary Melanoma.

Thomas NE, Edmiston SN, Alexander A, Groben PA, Parrish E, Kricker A, Armstrong BK, Anton-Culver H, Gruber SB, From L, Busam KJ, Hao H, Orlow I, Kanetsky PA, Luo L, Reiner AS, Paine S, Frank JS, Bramson JI, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Cust AE, Ollila DW, Begg CB, Berwick M, Conway K.

JAMA Oncol. 2015 Jun;1(3):359-368.


Identifying Etiologically Distinct Sub-Types of Cancer: A Demonstration Project Involving Breast Cancer.

Begg CB, Orlow I, Zabor EC, Arora A, Sharma A, Seshan VE, Bernstein JL.

Cancer Med. 2015 May 13. doi: 10.1002/cam4.456. [Epub ahead of print]


Proceedings of the second international molecular pathological epidemiology (MPE) meeting.

Ogino S, Campbell PT, Nishihara R, Phipps AI, Beck AH, Sherman ME, Chan AT, Troester MA, Bass AJ, Fitzgerald KC, Irizarry RA, Kelsey KT, Nan H, Peters U, Poole EM, Qian ZR, Tamimi RM, Tchetgen Tchetgen EJ, Tworoger SS, Zhang X, Giovannucci EL, van den Brandt PA, Rosner BA, Wang M, Chatterjee N, Begg CB.

Cancer Causes Control. 2015 Jul;26(7):959-72. doi: 10.1007/s10552-015-0596-2. Epub 2015 May 9.


Inherited genetic variants associated with occurrence of multiple primary melanoma.

Gibbs DC, Orlow I, Kanetsky PA, Luo L, Kricker A, Armstrong BK, Anton-Culver H, Gruber SB, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Sharma A, La Pilla E, From L, Busam KJ, Cust AE, Ollila DW, Begg CB, Berwick M, Thomas NE; GEM Study Group.

Cancer Epidemiol Biomarkers Prev. 2015 Jun;24(6):992-7. doi: 10.1158/1055-9965.EPI-14-1426. Epub 2015 Apr 2.


Inherited variation at MC1R and histological characteristics of primary melanoma.

Taylor NJ, Busam KJ, From L, Groben PA, Anton-Culver H, Cust AE, Begg CB, Dwyer T, Gallagher RP, Gruber SB, Orlow I, Rosso S, Thomas NE, Zanetti R, Rebbeck TR, Berwick M, Kanetsky PA.

PLoS One. 2015 Mar 19;10(3):e0119920. doi: 10.1371/journal.pone.0119920. eCollection 2015.


Ethical concerns about adaptive randomization.

Begg CB.

Clin Trials. 2015 Apr;12(2):101. doi: 10.1177/1740774515569613. No abstract available.


Genomic investigation of etiologic heterogeneity: methodologic challenges.

Begg CB, Seshan VE, Zabor EC, Furberg H, Arora A, Shen R, Maranchie JK, Nielsen ME, Rathmell WK, Signoretti S, Tamboli P, Karam JA, Choueiri TK, Hakimi AA, Hsieh JJ.

BMC Med Res Methodol. 2014 Dec 22;14:138. doi: 10.1186/1471-2288-14-138.


Inherited variation at MC1R and ASIP and association with melanoma-specific survival.

Taylor NJ, Reiner AS, Begg CB, Cust AE, Busam KJ, Anton-Culver H, Dwyer T, From L, Gallagher RP, Gruber SB, Rosso S, White KA, Zanetti R, Orlow I, Thomas NE, Rebbeck TR, Berwick M, Kanetsky PA; GEM Study Group.

Int J Cancer. 2015 Jun 1;136(11):2659-67. doi: 10.1002/ijc.29317. Epub 2014 Nov 26.


"Right to Try" laws.

Begg CB, Kim K, Neaton JD.

Clin Trials. 2014 Oct;11(5):519-20. doi: 10.1177/1740774514546574. No abstract available.


Comparison of clinicopathologic features and survival of histopathologically amelanotic and pigmented melanomas: a population-based study.

Thomas NE, Kricker A, Waxweiler WT, Dillon PM, Busman KJ, From L, Groben PA, Armstrong BK, Anton-Culver H, Gruber SB, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Venn A, Kanetsky PA, Orlow I, Paine S, Ollila DW, Reiner AS, Luo L, Hao H, Frank JS, Begg CB, Berwick M; Genes, Environment, and Melanoma (GEM) Study Group.

JAMA Dermatol. 2014 Dec;150(12):1306-314.


Sun exposure and melanoma survival: a GEM study.

Berwick M, Reiner AS, Paine S, Armstrong BK, Kricker A, Goumas C, Cust AE, Thomas NE, Groben PA, From L, Busam K, Orlow I, Marrett LD, Gallagher RP, Gruber SB, Anton-Culver H, Rosso S, Zanetti R, Kanetsky PA, Dwyer T, Venn A, Lee-Taylor J, Begg CB; GEM Study Group.

Cancer Epidemiol Biomarkers Prev. 2014 Oct;23(10):2145-52. doi: 10.1158/1055-9965.EPI-14-0431. Epub 2014 Jul 28.


Blocking and randomization to improve molecular biomarker discovery.

Qin LX, Zhou Q, Bogomolniy F, Villafania L, Olvera N, Cavatore M, Satagopan JM, Begg CB, Levine DA.

Clin Cancer Res. 2014 Jul 1;20(13):3371-8. doi: 10.1158/1078-0432.CCR-13-3155. Epub 2014 May 1.


Breast cancer after chest radiation therapy for childhood cancer.

Moskowitz CS, Chou JF, Wolden SL, Bernstein JL, Malhotra J, Novetsky Friedman D, Mubdi NZ, Leisenring WM, Stovall M, Hammond S, Smith SA, Henderson TO, Boice JD, Hudson MM, Diller LR, Bhatia S, Kenney LB, Neglia JP, Begg CB, Robison LL, Oeffinger KC.

J Clin Oncol. 2014 Jul 20;32(21):2217-23. doi: 10.1200/JCO.2013.54.4601. Epub 2014 Apr 21.


Editorial transition.

Begg CB.

Clin Trials. 2014 Feb;11(1):5-6. doi: 10.1177/1740774513515551. No abstract available.


MITF E318K's effect on melanoma risk independent of, but modified by, other risk factors.

Berwick M, MacArthur J, Orlow I, Kanetsky P, Begg CB, Luo L, Reiner A, Sharma A, Armstrong BK, Kricker A, Cust AE, Marrett LD, Gruber SB, Anton-Culver H, Zanetti R, Rosso S, Gallagher RP, Dwyer T, Venn A, Busam K, From L, White K, Thomas NE; GEM Study Group.

Pigment Cell Melanoma Res. 2014 May;27(3):485-8. doi: 10.1111/pcmr.12215. Epub 2014 Jan 30.


Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study.

Thomas NE, Busam KJ, From L, Kricker A, Armstrong BK, Anton-Culver H, Gruber SB, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Venn A, Kanetsky PA, Groben PA, Hao H, Orlow I, Reiner AS, Luo L, Paine S, Ollila DW, Wilcox H, Begg CB, Berwick M.

J Clin Oncol. 2013 Nov 20;31(33):4252-9. doi: 10.1200/JCO.2013.51.3002. Epub 2013 Oct 14.


Justifying the choice of endpoints for clinical trials.

Begg CB.

J Natl Cancer Inst. 2013 Nov 6;105(21):1594-5. doi: 10.1093/jnci/djt289. Epub 2013 Oct 9. No abstract available.


Testing the incremental predictive accuracy of new markers.

Begg CB, Gonen M, Seshan VE.

Clin Trials. 2013 Oct;10(5):690-2. doi: 10.1177/1740774513496490. Epub 2013 Jul 23.


A conceptual and methodological framework for investigating etiologic heterogeneity.

Begg CB, Zabor EC, Bernstein JL, Bernstein L, Press MF, Seshan VE.

Stat Med. 2013 Dec 20;32(29):5039-52. doi: 10.1002/sim.5902. Epub 2013 Jul 16.


An assessment of estimation methods for generalized linear mixed models with binary outcomes.

Capanu M, Gönen M, Begg CB.

Stat Med. 2013 Nov 20;32(26):4550-66. doi: 10.1002/sim.5866. Epub 2013 Jul 9.

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