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Results: 1 to 20 of 216

1.

Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma.

Mazan-Mamczarz K, Peroutka RJ, Steinhardt JJ, Gidoni M, Zhang Y, Lehrmann E, Landon AL, Dai B, Houng S, Muniandy PA, Efroni S, Becker KG, Gartenhaus RB.

Cell Commun Signal. 2015 Mar 1;13(1):15. doi: 10.1186/s12964-015-0091-0.

2.

Delineation of a conserved arrestin-biased signaling repertoire in vivo.

Maudsley S, Martin B, Gesty-Palmer D, Cheung H, Johnson C, Patel S, Becker KG, Wood WH 3rd, Zhang Y, Lehrmann E, Luttrell LM.

Mol Pharmacol. 2015 Apr;87(4):706-17. doi: 10.1124/mol.114.095224. Epub 2015 Jan 30.

3.

Age-associated changes in basal NF-κB function in human CD4+ T lymphocytes via dysregulation of PI3 kinase.

Bektas A, Zhang Y, Lehmann E, Wood WH 3rd, Becker KG, Madara K, Ferrucci L, Sen R.

Aging (Albany NY). 2014 Nov;6(11):957-74.

4.

DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.

Sykora P, Misiak M, Wang Y, Ghosh S, Leandro GS, Liu D, Tian J, Baptiste BA, Cong WN, Brenerman BM, Fang E, Becker KG, Hamilton RJ, Chigurupati S, Zhang Y, Egan JM, Croteau DL, Wilson DM 3rd, Mattson MP, Bohr VA.

Nucleic Acids Res. 2015 Jan;43(2):943-59. doi: 10.1093/nar/gku1356. Epub 2014 Dec 30.

5.

Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.

Cong WN, Chadwick W, Wang R, Daimon CM, Cai H, Amma J, Wood WH 3rd, Becker KG, Martin B, Maudsley S.

J Biol Chem. 2015 Jan 30;290(5):2728-43. doi: 10.1074/jbc.M114.588608. Epub 2014 Dec 11.

PMID:
25505248
6.

Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells.

Webster MR, Xu M, Kinzler KA, Kaur A, Appleton J, O'Connell MP, Marchbank K, Valiga A, Dang VM, Perego M, Zhang G, Slipicevic A, Keeney F, Lehrmann E, Wood W 3rd, Becker KG, Kossenkov AV, Frederick DT, Flaherty KT, Xu X, Herlyn M, Murphy ME, Weeraratna AT.

Pigment Cell Melanoma Res. 2015 Mar;28(2):184-95. doi: 10.1111/pcmr.12330. Epub 2014 Dec 29.

7.

MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.

Landon AL, Muniandy PA, Shetty AC, Lehrmann E, Volpon L, Houng S, Zhang Y, Dai B, Peroutka R, Mazan-Mamczarz K, Steinhardt J, Mahurkar A, Becker KG, Borden KL, Gartenhaus RB.

Nat Commun. 2014 Nov 18;5:5413. doi: 10.1038/ncomms6413.

8.

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity.

Yoon JH, De S, Srikantan S, Abdelmohsen K, Grammatikakis I, Kim J, Kim KM, Noh JH, White EJ, Martindale JL, Yang X, Kang MJ, Wood WH 3rd, Noren Hooten N, Evans MK, Becker KG, Tripathi V, Prasanth KV, Wilson GM, Tuschl T, Ingolia NT, Hafner M, Gorospe M.

Nat Commun. 2014 Nov 4;5:5248. doi: 10.1038/ncomms6248.

9.

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.

Mercken EM, Mitchell SJ, Martin-Montalvo A, Minor RK, Almeida M, Gomes AP, Scheibye-Knudsen M, Palacios HH, Licata JJ, Zhang Y, Becker KG, Khraiwesh H, González-Reyes JA, Villalba JM, Baur JA, Elliott P, Westphal C, Vlasuk GP, Ellis JL, Sinclair DA, Bernier M, de Cabo R.

Aging Cell. 2014 Oct;13(5):787-96. doi: 10.1111/acel.12220. Epub 2014 Jun 16.

10.

RNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels.

Panda AC, Abdelmohsen K, Yoon JH, Martindale JL, Yang X, Curtis J, Mercken EM, Chenette DM, Zhang Y, Schneider RJ, Becker KG, de Cabo R, Gorospe M.

Mol Cell Biol. 2014 Aug;34(16):3106-19. doi: 10.1128/MCB.00423-14. Epub 2014 Jun 2.

11.

Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice.

Lu H, Fang EF, Sykora P, Kulikowicz T, Zhang Y, Becker KG, Croteau DL, Bohr VA.

Cell Death Dis. 2014 May 15;5:e1226. doi: 10.1038/cddis.2014.168.

12.

A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.

Sherman-Baust CA, Kuhn E, Valle BL, Shih IeM, Kurman RJ, Wang TL, Amano T, Ko MS, Miyoshi I, Araki Y, Lehrmann E, Zhang Y, Becker KG, Morin PJ.

J Pathol. 2014 Jul;233(3):228-37. doi: 10.1002/path.4353.

PMID:
24652535
13.

Age-related brain expression and regulation of the chemokine CCL4/MIP-1β in APP/PS1 double-transgenic mice.

Zhu M, Allard JS, Zhang Y, Perez E, Spangler EL, Becker KG, Rapp PR.

J Neuropathol Exp Neurol. 2014 Apr;73(4):362-74. doi: 10.1097/NEN.0000000000000060.

14.

The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet.

Mitchell SJ, Martin-Montalvo A, Mercken EM, Palacios HH, Ward TM, Abulwerdi G, Minor RK, Vlasuk GP, Ellis JL, Sinclair DA, Dawson J, Allison DB, Zhang Y, Becker KG, Bernier M, de Cabo R.

Cell Rep. 2014 Mar 13;6(5):836-43. doi: 10.1016/j.celrep.2014.01.031. Epub 2014 Feb 27.

15.

Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.

Mazan-Mamczarz K, Zhao XF, Dai B, Steinhardt JJ, Peroutka RJ, Berk KL, Landon AL, Sadowska M, Zhang Y, Lehrmann E, Becker KG, Shaknovich R, Liu Z, Gartenhaus RB.

PLoS Genet. 2014 Jan 30;10(1):e1004105. doi: 10.1371/journal.pgen.1004105. eCollection 2014 Jan.

16.

Enhanced upregulation of CRH mRNA expression in the nucleus accumbens of male rats after a second injection of methamphetamine given thirty days later.

Cadet JL, Brannock C, Ladenheim B, McCoy MT, Krasnova IN, Lehrmann E, Becker KG, Jayanthi S.

PLoS One. 2014 Jan 27;9(1):e84665. doi: 10.1371/journal.pone.0084665. eCollection 2014.

17.

AMPK agonist AICAR improves cognition and motor coordination in young and aged mice.

Kobilo T, Guerrieri D, Zhang Y, Collica SC, Becker KG, van Praag H.

Learn Mem. 2014 Jan 17;21(2):119-26. doi: 10.1101/lm.033332.113.

18.

Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.

Fok WC, Chen Y, Bokov A, Zhang Y, Salmon AB, Diaz V, Javors M, Wood WH 3rd, Zhang Y, Becker KG, Pérez VI, Richardson A.

PLoS One. 2014 Jan 7;9(1):e83988. doi: 10.1371/journal.pone.0083988. eCollection 2014. Erratum in: PLoS One. 2014;9(4):e92346.

19.

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver.

Fok WC, Bokov A, Gelfond J, Yu Z, Zhang Y, Doderer M, Chen Y, Javors M, Wood WH 3rd, Zhang Y, Becker KG, Richardson A, Pérez VI.

Aging Cell. 2014 Apr;13(2):311-9. doi: 10.1111/acel.12175. Epub 2013 Dec 5.

20.

Age-related changes in microRNA levels in serum.

Noren Hooten N, Fitzpatrick M, Wood WH 3rd, De S, Ejiogu N, Zhang Y, Mattison JA, Becker KG, Zonderman AB, Evans MK.

Aging (Albany NY). 2013 Oct;5(10):725-40.

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