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Items: 1 to 20 of 51

1.

Rapamycin blocks induction of the thermogenic program in white adipose tissue.

Tran CM, Mukherjee S, Ye L, Frederick DW, Kissig M, Davis JG, Lamming DW, Seale P, Baur JA.

Diabetes. 2016 Feb 8. pii: db150502. [Epub ahead of print]

PMID:
26858361
2.

Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.

Toth P, Tarantini S, Davila A, Valcarcel-Ares MN, Tucsek Z, Varamini B, Ballabh P, Sonntag WE, Baur JA, Csiszar A, Ungvari Z.

Am J Physiol Heart Circ Physiol. 2015 Dec 1;309(11):H1837-45. doi: 10.1152/ajpheart.00463.2015. Epub 2015 Oct 9.

PMID:
26453330
3.

Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock.

Wang H, Guan Y, Karamercan MA, Ye L, Bhatti T, Becker LB, Baur JA, Sims CA.

Shock. 2015 Aug;44(2):173-80. doi: 10.1097/SHK.0000000000000390.

PMID:
25895148
4.

Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network.

Côté CD, Rasmussen BA, Duca FA, Zadeh-Tahmasebi M, Baur JA, Daljeet M, Breen DM, Filippi BM, Lam TK.

Nat Med. 2015 May;21(5):498-505. doi: 10.1038/nm.3821. Epub 2015 Apr 6.

PMID:
25849131
5.

Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival.

Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW.

FASEB J. 2015 Jun;29(6):2315-26. doi: 10.1096/fj.14-268409. Epub 2015 Feb 13.

PMID:
25681462
6.

Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.

Frederick DW, Davis JG, Dávila A Jr, Agarwal B, Michan S, Puchowicz MA, Nakamaru-Ogiso E, Baur JA.

J Biol Chem. 2015 Jan 16;290(3):1546-58. doi: 10.1074/jbc.M114.579565. Epub 2014 Nov 19.

7.

Rapamycin-induced metabolic defects are reversible in both lean and obese mice.

Liu Y, Diaz V, Fernandez E, Strong R, Ye L, Baur JA, Lamming DW, Richardson A, Salmon AB.

Aging (Albany NY). 2014 Sep;6(9):742-54.

8.

Resveratrol ameliorates mitochondrial dysfunction but increases the risk of hypoglycemia following hemorrhagic shock.

Wang H, Guan Y, Widlund AL, Becker LB, Baur JA, Reilly PM, Sims CA.

J Trauma Acute Care Surg. 2014 Dec;77(6):926-33. doi: 10.1097/TA.0000000000000358.

9.

Control of gluconeogenesis by metformin: does redox trump energy charge?

Baur JA, Birnbaum MJ.

Cell Metab. 2014 Aug 5;20(2):197-9. doi: 10.1016/j.cmet.2014.07.013.

10.

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.

Mercken EM, Mitchell SJ, Martin-Montalvo A, Minor RK, Almeida M, Gomes AP, Scheibye-Knudsen M, Palacios HH, Licata JJ, Zhang Y, Becker KG, Khraiwesh H, González-Reyes JA, Villalba JM, Baur JA, Elliott P, Westphal C, Vlasuk GP, Ellis JL, Sinclair DA, Bernier M, de Cabo R.

Aging Cell. 2014 Oct;13(5):787-96. doi: 10.1111/acel.12220. Epub 2014 Jun 16.

11.

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, Herbert RL, Tilmont EM, Ungvari Z, Pearson KJ, Lakatta EG, de Cabo R.

Cell Metab. 2014 Jul 1;20(1):183-90. doi: 10.1016/j.cmet.2014.04.018. Epub 2014 May 29.

12.

Extended wakefulness: compromised metabolics in and degeneration of locus ceruleus neurons.

Zhang J, Zhu Y, Zhan G, Fenik P, Panossian L, Wang MM, Reid S, Lai D, Davis JG, Baur JA, Veasey S.

J Neurosci. 2014 Mar 19;34(12):4418-31. doi: 10.1523/JNEUROSCI.5025-12.2014.

13.

Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism.

Naidoo N, Davis JG, Zhu J, Yabumoto M, Singletary K, Brown M, Galante R, Agarwal B, Baur JA.

Aging Cell. 2014 Feb;13(1):131-41. doi: 10.1111/acel.12158. Epub 2013 Nov 12.

14.

Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.

Jimenez-Gomez Y, Mattison JA, Pearson KJ, Martin-Montalvo A, Palacios HH, Sossong AM, Ward TM, Younts CM, Lewis K, Allard JS, Longo DL, Belman JP, Malagon MM, Navas P, Sanghvi M, Moaddel R, Tilmont EM, Herbert RL, Morrell CH, Egan JM, Baur JA, Ferrucci L, Bogan JS, Bernier M, de Cabo R.

Cell Metab. 2013 Oct 1;18(4):533-45. doi: 10.1016/j.cmet.2013.09.004.

15.

mTOR: more targets of resveratrol?

Widlund AL, Baur JA, Vang O.

Expert Rev Mol Med. 2013 Sep 23;15:e10. doi: 10.1017/erm.2013.11. Review.

PMID:
24060150
16.

Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance.

Ye L, Widlund AL, Sims CA, Lamming DW, Guan Y, Davis JG, Sabatini DM, Harrison DE, Vang O, Baur JA.

Aging (Albany NY). 2013 Jul;5(7):539-50.

17.

Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network.

Zhang Z, Tsukikawa M, Peng M, Polyak E, Nakamaru-Ogiso E, Ostrovsky J, McCormack S, Place E, Clarke C, Reiner G, McCormick E, Rappaport E, Haas R, Baur JA, Falk MJ.

PLoS One. 2013 Jul 24;8(7):e69282. doi: 10.1371/journal.pone.0069282. Print 2013.

18.

Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.

Lamming DW, Ye L, Astle CM, Baur JA, Sabatini DM, Harrison DE.

Aging Cell. 2013 Aug;12(4):712-8. doi: 10.1111/acel.12097. Epub 2013 Jun 7.

19.

Rapalogs and mTOR inhibitors as anti-aging therapeutics.

Lamming DW, Ye L, Sabatini DM, Baur JA.

J Clin Invest. 2013 Mar;123(3):980-9. doi: 10.1172/JCI64099. Epub 2013 Mar 1. Review.

20.

Resveratrol for primary prevention of atherosclerosis: clinical trial evidence for improved gene expression in vascular endothelium.

Agarwal B, Campen MJ, Channell MM, Wherry SJ, Varamini B, Davis JG, Baur JA, Smoliga JM.

Int J Cardiol. 2013 Jun 5;166(1):246-8. doi: 10.1016/j.ijcard.2012.09.027. Epub 2012 Oct 23. No abstract available.

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