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Germinal centres and B cell lymphomagenesis.

Basso K, Dalla-Favera R.

Nat Rev Immunol. 2015 Mar;15(3):172-84. doi: 10.1038/nri3814.


MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas.

Schneider C, Setty M, Holmes AB, Maute RL, Leslie CS, Mussolin L, Rosolen A, Dalla-Favera R, Basso K.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8185-90. doi: 10.1073/pnas.1322466111. Epub 2014 May 19.


An aberrant microRNA signature in childhood T-cell lymphoblastic lymphoma affecting CDKN1B expression, NOTCH1 and growth factor signaling pathways.

Mussolin L, Holmes AB, Romualdi C, Sales G, D'Amore ES, Ghisi M, Pillon M, Rosolen A, Basso K.

Leukemia. 2014 Sep;28(9):1909-12. doi: 10.1038/leu.2014.134. Epub 2014 Apr 14. No abstract available.


Deoxynivanelol and fumonisin, alone or in combination, induce changes on intestinal junction complexes and in E-cadherin expression.

Basso K, Gomes F, Bracarense AP.

Toxins (Basel). 2013 Nov 28;5(12):2341-52. doi: 10.3390/toxins5122341.


RNAs with multiple personalities.

Maute RL, Dalla-Favera R, Basso K.

Wiley Interdiscip Rev RNA. 2014 Jan-Feb;5(1):1-13. doi: 10.1002/wrna.1193. Epub 2013 Aug 20. Review.


MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.

Ying CY, Dominguez-Sola D, Fabi M, Lorenz IC, Hussein S, Bansal M, Califano A, Pasqualucci L, Basso K, Dalla-Favera R.

Nat Immunol. 2013 Oct;14(10):1084-92. doi: 10.1038/ni.2688. Epub 2013 Aug 25.


tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma.

Maute RL, Schneider C, Sumazin P, Holmes A, Califano A, Basso K, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1404-9. doi: 10.1073/pnas.1206761110. Epub 2013 Jan 7.


Gene expression profile analysis of lymphomas.

Basso K, Klein U.

Methods Mol Biol. 2013;971:213-26. doi: 10.1007/978-1-62703-269-8_12.


BCL6 positively regulates AID and germinal center gene expression via repression of miR-155.

Basso K, Schneider C, Shen Q, Holmes AB, Setty M, Leslie C, Dalla-Favera R.

J Exp Med. 2012 Dec 17;209(13):2455-65. doi: 10.1084/jem.20121387. Epub 2012 Nov 19.


A microRNA signature specific for hairy cell leukemia and associated with modulation of the MAPK-JNK pathways.

Kitagawa Y, Brahmachary M, Tiacci E, Dalla-Favera R, Falini B, Basso K.

Leukemia. 2012 Dec;26(12):2564-7. doi: 10.1038/leu.2012.149. Epub 2012 Jun 4. No abstract available.


Roles of BCL6 in normal and transformed germinal center B cells.

Basso K, Dalla-Favera R.

Immunol Rev. 2012 May;247(1):172-83. doi: 10.1111/j.1600-065X.2012.01112.x. Review.


T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses.

Basso K, Mussolin L, Lettieri A, Brahmachary M, Lim WK, Califano A, Basso G, Biondi A, Cazzaniga G, Rosolen A.

Genes Chromosomes Cancer. 2011 Dec;50(12):1063-75. doi: 10.1002/gcc.20924. Epub 2011 Aug 30.


Genomic analysis of non-splenic marginal zone lymphomas (MZL) indicates similarities between nodal and extranodal MZL and supports their derivation from memory B-cells.

Novak U, Basso K, Pasqualucci L, Dalla-Favera R, Bhagat G.

Br J Haematol. 2011 Nov;155(3):362-5. doi: 10.1111/j.1365-2141.2011.08841.x. Epub 2011 Aug 25.


Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150.

Ghisi M, Corradin A, Basso K, Frasson C, Serafin V, Mukherjee S, Mussolin L, Ruggero K, Bonanno L, Guffanti A, De Bellis G, Gerosa G, Stellin G, D'Agostino DM, Basso G, Bronte V, Indraccolo S, Amadori A, Zanovello P.

Blood. 2011 Jun 30;117(26):7053-62. doi: 10.1182/blood-2010-12-326629. Epub 2011 May 6.


A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.

Lefebvre C, Rajbhandari P, Alvarez MJ, Bandaru P, Lim WK, Sato M, Wang K, Sumazin P, Kustagi M, Bisikirska BC, Basso K, Beltrao P, Krogan N, Gautier J, Dalla-Favera R, Califano A.

Mol Syst Biol. 2010 Jun 8;6:377. doi: 10.1038/msb.2010.31.


BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis.

Basso K, Dalla-Favera R.

Adv Immunol. 2010;105:193-210. doi: 10.1016/S0065-2776(10)05007-8. Review.


Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

Basso K, Saito M, Sumazin P, Margolin AA, Wang K, Lim WK, Kitagawa Y, Schneider C, Alvarez MJ, Califano A, Dalla-Favera R.

Blood. 2010 Feb 4;115(5):975-84. doi: 10.1182/blood-2009-06-227017. Epub 2009 Dec 3.


Genome-wide identification of post-translational modulators of transcription factor activity in human B cells.

Wang K, Saito M, Bisikirska BC, Alvarez MJ, Lim WK, Rajbhandari P, Shen Q, Nemenman I, Basso K, Margolin AA, Klein U, Dalla-Favera R, Califano A.

Nat Biotechnol. 2009 Sep;27(9):829-39. doi: 10.1038/nbt.1563. Epub 2009 Sep 9.


BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma.

Saito M, Novak U, Piovan E, Basso K, Sumazin P, Schneider C, Crespo M, Shen Q, Bhagat G, Califano A, Chadburn A, Pasqualucci L, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11294-9. doi: 10.1073/pnas.0903854106. Epub 2009 Jun 23.


Identification of the human mature B cell miRNome.

Basso K, Sumazin P, Morozov P, Schneider C, Maute RL, Kitagawa Y, Mandelbaum J, Haddad J Jr, Chen CZ, Califano A, Dalla-Favera R.

Immunity. 2009 May;30(5):744-52. doi: 10.1016/j.immuni.2009.03.017. Epub 2009 May 14.

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