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Results: 1 to 20 of 149


Functional Characterization of Botulinum Neurotoxin Serotype H as a Hybrid of Known Serotypes F and A (BoNT F/A).

Kalb SR, Baudys J, Raphael BH, Dykes JK, Lúquez C, Maslanka SE, Barr JR.

Anal Chem. 2015 Mar 17. [Epub ahead of print]


High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures.

Boyer AE, Gallegos-Candela M, Quinn CP, Woolfitt AR, Brumlow JO, Isbell K, Hoffmaster AR, Lins RC, Barr JR.

Anal Bioanal Chem. 2015 Apr;407(10):2847-58. doi: 10.1007/s00216-015-8509-5. Epub 2015 Feb 12.


Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype.

Kull S, Schulz KM, Weisemann J, Kirchner S, Schreiber T, Bollenbach A, Dabrowski PW, Nitsche A, Kalb SR, Dorner MB, Barr JR, Rummel A, Dorner BG.

PLoS One. 2015 Feb 6;10(2):e0116381. doi: 10.1371/journal.pone.0116381. eCollection 2015.


Detection of Botulinum Toxins A, B, E, and F in Foods by Endopep-MS.

Kalb SR, Krilich JC, Dykes JK, Lúquez C, Maslanka SE, Barr JR.

J Agric Food Chem. 2015 Jan 22. [Epub ahead of print]


Quantification of ricin, RCA and comparison of enzymatic activity in 18 Ricinus communis cultivars by isotope dilution mass spectrometry.

Schieltz DM, McWilliams LG, Kuklenyik Z, Prezioso SM, Carter AJ, Williamson YM, McGrath SC, Morse SA, Barr JR.

Toxicon. 2015 Mar;95:72-83. doi: 10.1016/j.toxicon.2015.01.003. Epub 2015 Jan 7.


A two-stage multiplex method for quantitative analysis of botulinum neurotoxins type A, B, E, and F by MALDI-TOF mass spectrometry.

Wang D, Baudys J, Krilich J, Smith TJ, Barr JR, Kalb SR.

Anal Chem. 2014 Nov 4;86(21):10847-54. doi: 10.1021/ac502948v. Epub 2014 Oct 20.


Optimization of peptide substrates for botulinum neurotoxin E improves detection sensitivity in the Endopep-MS assay.

Wang D, Krilich J, Baudys J, Barr JR, Kalb SR.

Anal Biochem. 2014 Sep 16;468C:15-21. doi: 10.1016/j.ab.2014.08.026. [Epub ahead of print]


Detection of biomarkers of pathogenic Naegleria fowleri through mass spectrometry and proteomics.

Moura H, Izquierdo F, Woolfitt AR, Wagner G, Pinto T, del Aguila C, Barr JR.

J Eukaryot Microbiol. 2015 Jan-Feb;62(1):12-20. doi: 10.1111/jeu.12178. Epub 2014 Oct 28.


Validation of the Endopep-MS method for qualitative detection of active botulinum neurotoxins in human and chicken serum.

Björnstad K, Tevell Åberg A, Kalb SR, Wang D, Barr JR, Bondesson U, Hedeland M.

Anal Bioanal Chem. 2014 Nov;406(28):7149-61. doi: 10.1007/s00216-014-8170-4. Epub 2014 Sep 17.


Quantification of viral proteins of the avian H7 subtype of influenza virus: an isotope dilution mass spectrometry method applicable for producing more rapid vaccines in the case of an influenza pandemic.

Santana WI, Williams TL, Winne EK, Pirkle JL, Barr JR.

Anal Chem. 2014 May 6;86(9):4088-95. doi: 10.1021/ac4040778. Epub 2014 Apr 11.


Clostridium botulinum strains producing BoNT/F4 or BoNT/F5.

Raphael BH, Bradshaw M, Kalb SR, Joseph LA, Lúquez C, Barr JR, Johnson EA, Maslanka SE.

Appl Environ Microbiol. 2014 May;80(10):3250-7. doi: 10.1128/AEM.00284-14. Epub 2014 Mar 14.


Three enzymatically active neurotoxins of Clostridium botulinum strain Af84: BoNT/A2, /F4, and /F5.

Kalb SR, Baudys J, Smith TJ, Smith LA, Barr JR.

Anal Chem. 2014 Apr 1;86(7):3254-62. doi: 10.1021/ac5001509. Epub 2014 Mar 13.


Circulating lethal toxin decreases the ability of neutrophils to respond to Bacillus anthracis.

Weiner ZP, Ernst SM, Boyer AE, Gallegos-Candela M, Barr JR, Glomski IJ.

Cell Microbiol. 2014 Apr;16(4):504-18. doi: 10.1111/cmi.12232. Epub 2013 Nov 6.


Comparison of the catalytic properties of the botulinum neurotoxin subtypes A1 and A5.

Wang D, Krilich J, Pellett S, Baudys J, Tepp WH, Barr JR, Johnson EA, Kalb SR.

Biochim Biophys Acta. 2013 Dec;1834(12):2722-8. doi: 10.1016/j.bbapap.2013.09.007. Epub 2013 Oct 2.


Proteomic Analysis and Label-Free Quantification of the Large Clostridium difficile Toxins.

Moura H, Terilli RR, Woolfitt AR, Williamson YM, Wagner G, Blake TA, Solano MI, Barr JR.

Int J Proteomics. 2013;2013:293782. doi: 10.1155/2013/293782. Epub 2013 Aug 27.


Recovery and detection of botulinum neurotoxins from a nonporous surface.

Lautenschlager M, Maslanka SE, Paul PA, Kalb SR, Barr JR, Raphael BH.

J Microbiol Methods. 2013 Mar;92(3):278-80. doi: 10.1016/j.mimet.2012.12.019. Epub 2012 Dec 29.


The identification and characterization of epitopes in the 30-34 kDa Trypanosoma cruzi proteins recognized by antibodies in the serum samples of chagasic patients.

Verissimo da Costa GC, Lery LM, da Silva ML, Moura H, Peralta RH, von Krüger WM, Bisch PM, Barr JR, Peralta JM.

J Proteomics. 2013 Mar 27;80:34-42. doi: 10.1016/j.jprot.2012.11.001. Epub 2012 Nov 13.


Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype.

Raphael BH, Lautenschlager M, Kalb SR, de Jong LI, Frace M, Lúquez C, Barr JR, Fernández RA, Maslanka SE.

BMC Microbiol. 2012 Oct 31;12:245. doi: 10.1186/1471-2180-12-245.


Improved detection of botulinum neurotoxin serotype A by Endopep-MS through peptide substrate modification.

Wang D, Baudys J, Ye Y, Rees JC, Barr JR, Pirkle JL, Kalb SR.

Anal Biochem. 2013 Jan 15;432(2):115-23. doi: 10.1016/j.ab.2012.09.021. Epub 2012 Sep 24.


Subtyping botulinum neurotoxins by sequential multiple endoproteases in-gel digestion coupled with mass spectrometry.

Wang D, Baudys J, Rees J, Marshall KM, Kalb SR, Parks BA, Nowaczyk L 2nd, Pirkle JL, Barr JR.

Anal Chem. 2012 Jun 5;84(11):4652-8. doi: 10.1021/ac3006439. Epub 2012 May 21.

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