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S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis.

Mead RJ, Higginbottom A, Allen SP, Kirby J, Bennett E, Barber SC, Heath PR, Coluccia A, Patel N, Gardner I, Brancale A, Grierson AJ, Shaw PJ.

Free Radic Biol Med. 2013 Aug;61:438-52. doi: 10.1016/j.freeradbiomed.2013.04.018. Epub 2013 Apr 19.


A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function.

Sargsyan SA, Blackburn DJ, Barber SC, Grosskreutz J, De Vos KJ, Monk PN, Shaw PJ.

BMC Neurosci. 2011 Sep 23;12:91. doi: 10.1186/1471-2202-12-91.


Contrasting effects of cerebrospinal fluid from motor neuron disease patients on the survival of primary motor neurons cultured with or without glia.

Barber SC, Wood-Allum CA, Sargsyan SA, Walsh T, Cox LE, Monk PN, Shaw PJ.

Amyotroph Lateral Scler. 2011 Jul;12(4):257-63. doi: 10.3109/17482968.2011.560672. Epub 2011 Mar 3.


Oxidative stress in ALS: key role in motor neuron injury and therapeutic target.

Barber SC, Shaw PJ.

Free Radic Biol Med. 2010 Mar 1;48(5):629-41. doi: 10.1016/j.freeradbiomed.2009.11.018. Epub 2009 Dec 4. Review.


Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1.

Sargsyan SA, Blackburn DJ, Barber SC, Monk PN, Shaw PJ.

Neuroreport. 2009 Oct 28;20(16):1450-5. doi: 10.1097/WNR.0b013e328331e8fa.


An in vitro screening cascade to identify neuroprotective antioxidants in ALS.

Barber SC, Higginbottom A, Mead RJ, Barber S, Shaw PJ.

Free Radic Biol Med. 2009 Apr 15;46(8):1127-38. doi: 10.1016/j.freeradbiomed.2009.01.019. Epub 2009 Jan 30.


Chapter 4 Molecular mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis.

Barber SC, Shaw PJ.

Handb Clin Neurol. 2007;82:57-87. doi: 10.1016/S0072-9752(07)80007-8. No abstract available.


Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.

Barber SC, Mead RJ, Shaw PJ.

Biochim Biophys Acta. 2006 Nov-Dec;1762(11-12):1051-67. Epub 2006 Apr 4. Review.


Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen.

Wood-Allum CA, Barber SC, Kirby J, Heath P, Holden H, Mead R, Higginbottom A, Allen S, Beaujeux T, Alexson SE, Ince PG, Shaw PJ.

Brain. 2006 Jul;129(Pt 7):1693-709. Epub 2006 May 15.


Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.

Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, Barber SC, Loynes CA, Wood-Allum CA, Lunec J, Shaw PJ.

Brain. 2005 Jul;128(Pt 7):1686-706. Epub 2005 May 4.


S1P and LPA trigger Schwann cell actin changes and migration.

Barber SC, Mellor H, Gampel A, Scolding NJ.

Eur J Neurosci. 2004 Jun;19(12):3142-50.


Corticosterone and methylation of noradrenaline in vitro.

Barber SC, Coupland RE, Crowe J.

J Physiol. 1972 Apr;222(1):29P. No abstract available.


Corticosterone and methylation of noradrenaline in vitro.

Coupland RE, Barber SC, Crowe J.

J Anat. 1972 Feb;111(Pt 2):326. No abstract available.

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