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Items: 1 to 20 of 51

1.

The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells.

Badia R, Pujantell M, Riveira-Muñoz E, Puig T, Torres-Torronteras J, Martí R, Clotet B, Ampudia RM, Vives-Pi M, Esté JA, Ballana E.

PLoS Pathog. 2016 Aug 19;12(8):e1005829. doi: 10.1371/journal.ppat.1005829. eCollection 2016 Aug.

2.

Long-term HIV-1 infection induces an antiviral state in primary macrophages.

Pujantell M, Badia R, Ramirez C, Puig T, Clotet B, Ballana E, Esté JA, Riveira-Muñoz E.

Antiviral Res. 2016 Aug 7;133:145-155. doi: 10.1016/j.antiviral.2016.08.004. [Epub ahead of print]

PMID:
27510577
3.

Inhibition of herpes simplex virus type 1 by the CDK6 inhibitor PD-0332991 (palbociclib) through the control of SAMHD1.

Badia R, Angulo G, Riveira-Muñoz E, Pujantell M, Puig T, Ramirez C, Torres-Torronteras J, Martí R, Pauls E, Clotet B, Ballana E, Esté JA.

J Antimicrob Chemother. 2016 Feb;71(2):387-94. doi: 10.1093/jac/dkv363. Epub 2015 Nov 4.

PMID:
26542306
4.

SAMHD1: at the crossroads of cell proliferation, immune responses, and virus restriction.

Ballana E, Esté JA.

Trends Microbiol. 2015 Nov;23(11):680-92. doi: 10.1016/j.tim.2015.08.002. Epub 2015 Oct 1. Review.

PMID:
26439297
5.

BMS-663068, a safe and effective HIV-1 attachment inhibitor.

Ballana E, Esté JA.

Lancet HIV. 2015 Oct;2(10):e404-5. doi: 10.1016/S2352-3018(15)00160-5. Epub 2015 Sep 2. No abstract available.

PMID:
26423643
6.

The thioacetate-ω(γ-lactam carboxamide) HDAC inhibitor ST7612AA1 as HIV-1 latency reactivation agent.

Badia R, Grau J, Riveira-Muñoz E, Ballana E, Giannini G, Esté JA.

Antiviral Res. 2015 Nov;123:62-9. doi: 10.1016/j.antiviral.2015.09.004. Epub 2015 Sep 5.

PMID:
26348004
7.

Cyclin D3-dependent control of the dNTP pool and HIV-1 replication in human macrophages.

Ruiz A, Pauls E, Badia R, Torres-Torronteras J, Riveira-Muñoz E, Clotet B, Martí R, Ballana E, Esté JA.

Cell Cycle. 2015;14(11):1657-65. doi: 10.1080/15384101.2015.1030558.

8.

Characterization of the influence of mediator complex in HIV-1 transcription.

Ruiz A, Pauls E, Badia R, Riveira-Muñoz E, Clotet B, Ballana E, Esté JA.

J Biol Chem. 2014 Oct 3;289(40):27665-76. doi: 10.1074/jbc.M114.570341. Epub 2014 Aug 6.

9.

Increased expression of SAMHD1 in a subset of HIV-1 elite controllers.

Riveira-Muñoz E, Ruiz A, Pauls E, Permanyer M, Badia R, Mothe B, Crespo M, Clotet B, Brander C, Ballana E, Esté JA.

J Antimicrob Chemother. 2014 Nov;69(11):3057-60. doi: 10.1093/jac/dku276. Epub 2014 Jul 25.

10.

Palbociclib, a selective inhibitor of cyclin-dependent kinase4/6, blocks HIV-1 reverse transcription through the control of sterile α motif and HD domain-containing protein-1 (SAMHD1) activity.

Pauls E, Badia R, Torres-Torronteras J, Ruiz A, Permanyer M, Riveira-Muñoz E, Clotet B, Marti R, Ballana E, Esté JA.

AIDS. 2014 Sep 24;28(15):2213-22. doi: 10.1097/QAD.0000000000000399.

PMID:
25036183
11.

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells.

Pauls E, Ruiz A, Badia R, Permanyer M, Gubern A, Riveira-Muñoz E, Torres-Torronteras J, Alvarez M, Mothe B, Brander C, Crespo M, Menéndez-Arias L, Clotet B, Keppler OT, Martí R, Posas F, Ballana E, Esté JA.

J Immunol. 2014 Aug 15;193(4):1988-97. doi: 10.4049/jimmunol.1400873. Epub 2014 Jul 11.

12.

SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.

Ballana E, Badia R, Terradas G, Torres-Torronteras J, Ruiz A, Pauls E, Riveira-Muñoz E, Clotet B, Martí R, Esté JA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4804-13. doi: 10.1128/AAC.03145-14. Epub 2014 Jun 9.

13.

Zinc finger endonuclease targeting PSIP1 inhibits HIV-1 integration.

Badia R, Pauls E, Riveira-Munoz E, Clotet B, Esté JA, Ballana E.

Antimicrob Agents Chemother. 2014 Aug;58(8):4318-27. doi: 10.1128/AAC.02690-14. Epub 2014 May 12.

14.

Gene editing using a zinc-finger nuclease mimicking the CCR5Δ32 mutation induces resistance to CCR5-using HIV-1.

Badia R, Riveira-Muñoz E, Clotet B, Esté JA, Ballana E.

J Antimicrob Chemother. 2014 Jul;69(7):1755-9. doi: 10.1093/jac/dku072. Epub 2014 Mar 20.

15.

p21 regulates the HIV-1 restriction factor SAMHD1.

Pauls E, Ruiz A, Riveira-Muñoz E, Permanyer M, Badia R, Clotet B, Keppler OT, Ballana E, Este JA.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1322-4. doi: 10.1073/pnas.1322059111. Epub 2014 Mar 7. No abstract available.

16.

The cortical actin determines different susceptibility of naïve and memory CD4+ T cells to HIV-1 cell-to-cell transmission and infection.

Permanyer M, Pauls E, Badia R, Esté JA, Ballana E.

PLoS One. 2013 Nov 11;8(11):e79221. doi: 10.1371/journal.pone.0079221. eCollection 2013.

17.

Insights from host genomics into HIV infection and disease: Identification of host targets for drug development.

Ballana E, Esté JA.

Antiviral Res. 2013 Nov;100(2):473-86. doi: 10.1016/j.antiviral.2013.09.017. Epub 2013 Sep 29. Review.

PMID:
24084487
18.

Restriction of HIV-1 replication in primary macrophages by IL-12 and IL-18 through the upregulation of SAMHD1.

Pauls E, Jimenez E, Ruiz A, Permanyer M, Ballana E, Costa H, Nascimiento R, Parkhouse RM, Peña R, Riveiro-Muñoz E, Martinez MA, Clotet B, Esté JA, Bofill M.

J Immunol. 2013 May 1;190(9):4736-41. doi: 10.4049/jimmunol.1203226. Epub 2013 Mar 22.

19.

Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo.

Koh Y, Ballana E, Este J, Engelman A.

AIDS. 2013 Feb 20;27(4):665-7. doi: 10.1097/QAD.0b013e32835af34c. No abstract available.

20.

Nucleotide embargo by SAMHD1: a strategy to block retroviral infection.

Pauls E, Ballana E, Esté JA.

Antiviral Res. 2013 Feb;97(2):180-2. doi: 10.1016/j.antiviral.2012.12.009. Epub 2012 Dec 21.

PMID:
23266292
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