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Results: 1 to 20 of 52


WNT-inflammasome signaling mediates NOD2-induced development of acute arthritis in mice.

Singh V, Holla S, Ramachandra SG, Balaji KN.

J Immunol. 2015 Apr 1;194(7):3351-60. doi: 10.4049/jimmunol.1402498. Epub 2015 Feb 25.


Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation.

Maddur MS, Trinath J, Rabin M, Bolgert F, Guy M, Vallat JM, Magy L, Balaji KN, Kaveri SV, Bayry J.

Cell Mol Immunol. 2014 Dec 8. doi: 10.1038/cmi.2014.117. [Epub ahead of print] No abstract available.


Anthrapyrazolone analogues intercept inflammatory JNK signals to moderate endotoxin induced septic shock.

Prasad KD, Trinath J, Biswas A, Sekar K, Balaji KN, Guru Row TN.

Sci Rep. 2014 Nov 27;4:7214. doi: 10.1038/srep07214.


Inhibition of programmed death 1 ligand 1 on dendritic cells enhances Mycobacterium-mediated interferon γ (IFN-γ) production without modulating the frequencies of IFN-γ-producing CD4+ T cells.

Stephen-Victor E, Saha C, Sharma M, Holla S, Balaji KN, Kaveri SV, Bayry J.

J Infect Dis. 2015 Mar 15;211(6):1027-9. doi: 10.1093/infdis/jiu532. Epub 2014 Sep 25. No abstract available.


The WNT signaling pathway contributes to dectin-1-dependent inhibition of Toll-like receptor-induced inflammatory signature.

Trinath J, Holla S, Mahadik K, Prakhar P, Singh V, Balaji KN.

Mol Cell Biol. 2014 Dec 1;34(23):4301-14. doi: 10.1128/MCB.00641-14. Epub 2014 Sep 22.


Mycobacterium bovis BCG promotes tumor cell survival from tumor necrosis factor-α-induced apoptosis.

Holla S, Ghorpade DS, Singh V, Bansal K, Balaji KN.

Mol Cancer. 2014 Sep 11;13:210. doi: 10.1186/1476-4598-13-210.


Alkyl chain substituted 1,9-pyrazoloanthrones exhibit prominent inhibitory effect on c-Jun N-terminal kinase (JNK).

Prasad KD, Trinath J, Biswas A, Sekar K, Balaji KN, Guru Row TN.

Org Biomol Chem. 2014 Jul 14;12(26):4656-62. doi: 10.1039/c4ob00548a.


TNF-α modulates TLR2-dependent responses during mycobacterial infection.

Holla S, Trinath J, Balaji KN.

Methods Mol Biol. 2014;1155:133-50. doi: 10.1007/978-1-4939-0669-7_12.


Progress in tuberculosis vaccine development and host-directed therapies--a state of the art review.

Kaufmann SH, Lange C, Rao M, Balaji KN, Lotze M, Schito M, Zumla AI, Maeurer M.

Lancet Respir Med. 2014 Apr;2(4):301-20. doi: 10.1016/S2213-2600(14)70033-5. Epub 2014 Mar 24. Review.


GM-CSF along with IL-4 but not alone is indispensable for the differentiation of human dendritic cells from monocytes.

Holla S, Sharma M, Vani J, Kaveri SV, Balaji KN, Bayry J.

J Allergy Clin Immunol. 2014 May;133(5):1500-2, 1502.e1. doi: 10.1016/j.jaci.2014.02.021. Epub 2014 Apr 1. No abstract available.


Selective inhibition of IFNG-induced autophagy by Mir155- and Mir31-responsive WNT5A and SHH signaling.

Holla S, Kurowska-Stolarska M, Bayry J, Balaji KN.

Autophagy. 2014 Feb;10(2):311-30. doi: 10.4161/auto.27225. Epub 2013 Dec 10.


NOD2-nitric oxide-responsive microRNA-146a activates Sonic hedgehog signaling to orchestrate inflammatory responses in murine model of inflammatory bowel disease.

Ghorpade DS, Sinha AY, Holla S, Singh V, Balaji KN.

J Biol Chem. 2013 Nov 15;288(46):33037-48. doi: 10.1074/jbc.M113.492496. Epub 2013 Oct 3.


Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells.

Trinath J, Hegde P, Sharma M, Maddur MS, Rabin M, Vallat JM, Magy L, Balaji KN, Kaveri SV, Bayry J.

Blood. 2013 Aug 22;122(8):1419-27. doi: 10.1182/blood-2012-11-468264. Epub 2013 Jul 11.


Mycobacterium tuberculosis cell wall-associated Rv3812 protein induces strong dendritic cell-mediated interferon γ responses and exhibits vaccine potential.

Vani J, Shaila MS, Trinath J, Balaji KN, Kaveri SV, Bayry J.

J Infect Dis. 2013 Sep;208(6):1034-6. doi: 10.1093/infdis/jit281. Epub 2013 Jun 20. No abstract available.


Nitric oxide and KLF4 protein epigenetically modify class II transactivator to repress major histocompatibility complex II expression during Mycobacterium bovis bacillus Calmette-Guerin infection.

Ghorpade DS, Holla S, Sinha AY, Alagesan SK, Balaji KN.

J Biol Chem. 2013 Jul 12;288(28):20592-606. doi: 10.1074/jbc.M113.472183. Epub 2013 Jun 3.


Differential cellular recognition pattern to M. tuberculosis targets defined by IFN-γ and IL-17 production in blood from TB + patients from Honduras as compared to health care workers: TB and immune responses in patients from Honduras.

Alvarez-Corrales N, Ahmed RK, Rodriguez CA, Balaji KN, Rivera R, Sompallae R, Vudattu NK, Hoffner SE, Zumla A, Pineda-Garcia L, Maeurer M.

BMC Infect Dis. 2013 Mar 6;13:125. doi: 10.1186/1471-2334-13-125.


Intravenous immunoglobulin-mediated regulation of Notch ligands on human dendritic cells.

Trinath J, Hegde P, Balaji KN, Kaveri SV, Bayry J.

J Allergy Clin Immunol. 2013 Apr;131(4):1255-7, 1257.e1. doi: 10.1016/j.jaci.2013.01.031. Epub 2013 Mar 1. No abstract available.


Serodiagnosis of tuberculosis in Asian elephants (Elephas maximus) in Southern India: a latent class analysis.

Verma-Kumar S, Abraham D, Dendukuri N, Cheeran JV, Sukumar R, Balaji KN.

PLoS One. 2012;7(11):e49548. doi: 10.1371/journal.pone.0049548. Epub 2012 Nov 16.


Sonic hedgehog-dependent induction of microRNA 31 and microRNA 150 regulates Mycobacterium bovis BCG-driven toll-like receptor 2 signaling.

Ghorpade DS, Holla S, Kaveri SV, Bayry J, Patil SA, Balaji KN.

Mol Cell Biol. 2013 Feb;33(3):543-56. doi: 10.1128/MCB.01108-12. Epub 2012 Nov 19.


MicroRNA-155 is required for Mycobacterium bovis BCG-mediated apoptosis of macrophages.

Ghorpade DS, Leyland R, Kurowska-Stolarska M, Patil SA, Balaji KN.

Mol Cell Biol. 2012 Jun;32(12):2239-53. doi: 10.1128/MCB.06597-11. Epub 2012 Apr 2.

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