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Items: 1 to 20 of 168

1.

Ciliopathy-associated IQCB1/NPHP5 protein is required for mouse photoreceptor outer segment formation.

Ronquillo CC, Hanke-Gogokhia C, Revelo MP, Frederick JM, Jiang L, Baehr W.

FASEB J. 2016 Jun 21. pii: fj.201600511R. [Epub ahead of print]

PMID:
27328943
2.

Knockdown of unc119c results in visual impairment and early-onset retinal dystrophy in zebrafish.

Rainy N, Etzion T, Alon S, Pomeranz A, Nisgav Y, Livnat T, Bach M, Gerstner CD, Baehr W, Gothilf Y, Stiebel-Kalish H.

Biochem Biophys Res Commun. 2016 May 13;473(4):1211-7. doi: 10.1016/j.bbrc.2016.04.041. Epub 2016 Apr 11.

PMID:
27079236
3.

Ciliopathy-associated protein CEP290 modifies the severity of retinal degeneration due to loss of RPGR.

Rao KN, Zhang W, Li L, Ronquillo C, Baehr W, Khanna H.

Hum Mol Genet. 2016 Mar 2. pii: ddw075. [Epub ahead of print]

PMID:
26936822
4.

Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.

Hanke-Gogokhia C, Wu Z, Gerstner CD, Frederick JM, Zhang H, Baehr W.

J Biol Chem. 2016 Mar 25;291(13):7142-55. doi: 10.1074/jbc.M115.710954. Epub 2016 Jan 25.

PMID:
26814127
5.

The Function of Arf-like Proteins ARL2 and ARL3 in Photoreceptors.

Hanke-Gogokhia C, Zhang H, Frederick JM, Baehr W.

Adv Exp Med Biol. 2016;854:655-61. doi: 10.1007/978-3-319-17121-0_87.

PMID:
26427472
6.

Kinesin family 17 (osmotic avoidance abnormal-3) is dispensable for photoreceptor morphology and function.

Jiang L, Tam BM, Ying G, Wu S, Hauswirth WW, Frederick JM, Moritz OL, Baehr W.

FASEB J. 2015 Dec;29(12):4866-80. doi: 10.1096/fj.15-275677. Epub 2015 Jul 30.

PMID:
26229057
7.

Domain organization and conformational plasticity of the G protein effector, PDE6.

Zhang Z, He F, Constantine R, Baker ML, Baehr W, Schmid MF, Wensel TG, Agosto MA.

J Biol Chem. 2015 Jul 10;290(28):17131-2. doi: 10.1074/jbc.A115.647636. No abstract available.

8.

cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.

Ma H, Butler MR, Thapa A, Belcher J, Yang F, Baehr W, Biel M, Michalakis S, Ding XQ.

J Biol Chem. 2015 Aug 21;290(34):20880-92. doi: 10.1074/jbc.M115.641159. Epub 2015 Jun 29.

PMID:
26124274
9.

Heterotrimeric kinesin-2 (KIF3) mediates transition zone and axoneme formation of mouse photoreceptors.

Jiang L, Wei Y, Ronquillo CC, Marc RE, Yoder BK, Frederick JM, Baehr W.

J Biol Chem. 2015 May 15;290(20):12765-78. doi: 10.1074/jbc.M115.638437. Epub 2015 Mar 30.

10.

Domain organization and conformational plasticity of the G protein effector, PDE6.

Zhang Z, He F, Constantine R, Baker ML, Baehr W, Schmid MF, Wensel TG, Agosto MA.

J Biol Chem. 2015 May 15;290(20):12833-43. doi: 10.1074/jbc.M115.647636. Epub 2015 Mar 25. Erratum in: J Biol Chem. 2015 Jul 10;290(28):17131-2.

11.

Ca(2+) and Ca(2+)-interlocked membrane guanylate cyclase signal modulation of neuronal and cardiovascular signal transduction.

Sharma RK, Baehr W, Makino CL, Duda T.

Front Mol Neurosci. 2015 Mar 6;8:7. doi: 10.3389/fnmol.2015.00007. eCollection 2015. No abstract available.

12.

Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling.

Tracy CM, Kolesnikov AV, Blake DR, Chen CK, Baehr W, Kefalov VJ, Willardson BM.

PLoS One. 2015 Feb 6;10(2):e0117129. doi: 10.1371/journal.pone.0117129. eCollection 2015.

13.

Membrane protein transport in photoreceptors: the function of PDEδ: the Proctor lecture.

Baehr W.

Invest Ophthalmol Vis Sci. 2014 Dec 30;55(12):8653-66. doi: 10.1167/iovs.14-16066.

14.

Mistrafficking of prenylated proteins causes retinitis pigmentosa 2.

Zhang H, Hanke-Gogokhia C, Jiang L, Li X, Wang P, Gerstner CD, Frederick JM, Yang Z, Baehr W.

FASEB J. 2015 Mar;29(3):932-42. doi: 10.1096/fj.14-257915. Epub 2014 Nov 24.

15.

Inactivity of human β,β-carotene-9',10'-dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigment.

Li B, Vachali PP, Gorusupudi A, Shen Z, Sharifzadeh H, Besch BM, Nelson K, Horvath MM, Frederick JM, Baehr W, Bernstein PS.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10173-8. doi: 10.1073/pnas.1402526111. Epub 2014 Jun 30.

16.

FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.

Owen LA, Morrison MA, Ahn J, Woo SJ, Sato H, Robinson R, Morgan DJ, Zacharaki F, Simeonova M, Uehara H, Chakravarthy U, Hogg RE, Ambati BK, Kotoula M, Baehr W, Haider NB, Silvestri G, Miller JW, Tsironi EE, Farrer LA, Kim IK, Park KH, DeAngelis MM.

Invest Ophthalmol Vis Sci. 2014 May 8;55(6):3543-54. doi: 10.1167/iovs.14-14047.

17.

Centrin 2 is required for mouse olfactory ciliary trafficking and development of ependymal cilia planar polarity.

Ying G, Avasthi P, Irwin M, Gerstner CD, Frederick JM, Lucero MT, Baehr W.

J Neurosci. 2014 Apr 30;34(18):6377-88. doi: 10.1523/JNEUROSCI.0067-14.2014.

18.

RNA interference gene therapy in dominant retinitis pigmentosa and cone-rod dystrophy mouse models caused by GCAP1 mutations.

Jiang L, Frederick JM, Baehr W.

Front Mol Neurosci. 2014 Apr 7;7:25. doi: 10.3389/fnmol.2014.00025. eCollection 2014. Review.

19.

Unc119 gene deletion partially rescues the GRK1 transport defect of Pde6d (- /-) cones.

Zhang H, Frederick JM, Baehr W.

Adv Exp Med Biol. 2014;801:487-93. doi: 10.1007/978-1-4614-3209-8_62.

20.

Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.

Ma H, Thapa A, Morris L, Redmond TM, Baehr W, Ding XQ.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3602-7. doi: 10.1073/pnas.1317041111. Epub 2014 Feb 18.

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