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Physical Mapping and Refinement of the Painted Turtle Genome (Chrysemys picta) Inform Amniote Genome Evolution and Challenge Turtle-Bird Chromosomal Conservation.

Badenhorst D, Hillier LW, Literman R, Montiel EE, Radhakrishnan S, Shen Y, Minx P, Janes DE, Warren WC, Edwards SV, Valenzuela N.

Genome Biol Evol. 2015 Jun 24;7(7):2038-50. doi: 10.1093/gbe/evv119.


Molecular cytogenetic search for cryptic sex chromosomes in painted turtles Chrysemys picta.

Valenzuela N, Badenhorst D, Montiel EE, Literman R.

Cytogenet Genome Res. 2014;144(1):39-46. doi: 10.1159/000366076. Epub 2014 Aug 28.


The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage.

Shaffer HB, Minx P, Warren DE, Shedlock AM, Thomson RC, Valenzuela N, Abramyan J, Amemiya CT, Badenhorst D, Biggar KK, Borchert GM, Botka CW, Bowden RM, Braun EL, Bronikowski AM, Bruneau BG, Buck LT, Capel B, Castoe TA, Czerwinski M, Delehaunty KD, Edwards SV, Fronick CC, Fujita MK, Fulton L, Graves TA, Green RE, Haerty W, Hariharan R, Hernandez O, Hillier LW, Holloway AK, Janes D, Janzen FJ, Kandoth C, Kong L, de Koning AP, Li Y, Literman R, McGaugh SE, Mork L, O'Laughlin M, Paitz RT, Pollock DD, Ponting CP, Radhakrishnan S, Raney BJ, Richman JM, St John J, Schwartz T, Sethuraman A, Spinks PQ, Storey KB, Thane N, Vinar T, Zimmerman LM, Warren WC, Mardis ER, Wilson RK.

Genome Biol. 2013 Mar 28;14(3):R28. doi: 10.1186/gb-2013-14-3-r28.


A ZZ/ZW microchromosome system in the spiny softshell turtle, Apalone spinifera, reveals an intriguing sex chromosome conservation in Trionychidae.

Badenhorst D, Stanyon R, Engstrom T, Valenzuela N.

Chromosome Res. 2013 Apr;21(2):137-47. doi: 10.1007/s10577-013-9343-2. Epub 2013 Mar 20.


Host cell/Orientia tsutsugamushi interactions: evolution and expression of syndecan-4 in Asian rodents (Rodentia, Muridae).

Badenhorst D, Tatard C, Suputtamongkol Y, Robinson TJ, Dobigny G.

Infect Genet Evol. 2012 Jul;12(5):1136-46. doi: 10.1016/j.meegid.2012.03.020. Epub 2012 Mar 30.


Karyotypic evolution of hapalomys inferred from chromosome painting: a detailed characterization contributing new insights into the ancestral murinae karyotype.

Badenhorst D, Dobigny G, Robinson TJ.

Cytogenet Genome Res. 2012;136(2):83-8. doi: 10.1159/000335286. Epub 2012 Jan 4.


Chromosomal evolution in Rattini (Muridae, Rodentia).

Badenhorst D, Dobigny G, Adega F, Chaves R, O'Brien PC, Ferguson-Smith MA, Waters PD, Robinson TJ.

Chromosome Res. 2011 Aug;19(6):709-27. doi: 10.1007/s10577-011-9227-2. Epub 2011 Aug 18.


Impact of aldosterone receptor blockade on the deleterious cardiac effects of adrenergic activation in hypertensive rats.

Veliotes DG, Norton GR, Correia RJ, Strijdom H, Badenhorst D, Brooksbank R, Woodiwiss AJ.

J Cardiovasc Pharmacol. 2010 Aug;56(2):203-11. doi: 10.1097/FJC.0b013e3181e92a01.


Beta1- and alpha2c-adrenoreceptor variants as predictors of clinical aspects of dilated cardiomyopathy in people of African ancestry.

Woodiwiss AJ, Badenhorst D, Sliwa K, Brooksbank R, Essop R, Sareli P, Norton GR.

Cardiovasc J Afr. 2008 Jul-Aug;19(4):188-93.


Impact of beta2-adrenoreceptor gene variants on cardiac cavity size and systolic function in idiopathic dilated cardiomyopathy.

Badenhorst D, Norton GR, Sliwa K, Brooksbank R, Essop R, Sareli P, Woodiwiss AJ.

Pharmacogenomics J. 2007 Oct;7(5):339-45. Epub 2006 Nov 21.


Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin.

Woodiwiss AJ, Nkeh B, Samani NJ, Badenhorst D, Maseko M, Tiago AD, Candy GP, Libhaber E, Sareli P, Brooksbank R, Norton GR.

J Hypertens. 2006 Jun;24(6):1057-64.


Endotoxin-independent white cell cytokine production in haemodynamically stable patients with idiopathic dilated cardiomyopathy.

Brooksbank R, Woodiwiss AJ, Sliwa K, Badenhorst D, Deftereos D, Wadee AA, Essop MR, Sareli P, Norton GR.

Cardiovasc J S Afr. 2005 Sep-Oct;16(5):260-5.


Phosphodiesterase inhibition promotes the transition from compensated hypertrophy to cardiac dilatation in rats.

Anamourlis C, Badenhorst D, Gibbs M, Correia R, Veliotes D, Osadchii O, Norton GR, Woodiwiss AJ.

Pflugers Arch. 2006 Jan;451(4):526-33. Epub 2005 Oct 7.


Impact and mechanisms of action of neurotensin on cardiac contractility in the rat left ventricle.

Osadchii O, Norton G, Deftereos D, Badenhorst D, Woodiwiss A.

Eur J Pharmacol. 2005 Sep 27;520(1-3):108-17.


A phosphodiesterase inhibitor promotes the premature development of adverse cardiac remodelling mediated by beta-adrenergic activation in hypertension.

Badenhorst D, Anamourlis C, Gibbs M, Maseko M, Osadchii O, Woodiwiss AJ, Norton GR.

S Afr Med J. 2004 Oct;94(10):833-4. No abstract available.


Chronic beta-adrenoreceptor activation increases cardiac cavity size through chamber remodeling and not via modifications in myocardial material properties.

Gibbs M, Veliotes DG, Anamourlis C, Badenhorst D, Osadchii O, Norton GR, Woodiwiss AJ.

Am J Physiol Heart Circ Physiol. 2004 Dec;287(6):H2762-7. Epub 2004 Aug 19.


Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: results of a randomized study.

Sliwa K, Woodiwiss A, Kone VN, Candy G, Badenhorst D, Norton G, Zambakides C, Peters F, Essop R.

Circulation. 2004 Feb 17;109(6):750-5.


Impact of renin-angiotensin-aldosterone system gene variants on the severity of hypertension in patients with newly diagnosed hypertension.

Tiago AD, Badenhorst D, Nkeh B, Candy GP, Brooksbank R, Sareli P, Libhaber E, Samani NJ, Woodiwiss AJ, Norton GR.

Am J Hypertens. 2003 Dec;16(12):1006-10.


T594M variant of the epithelial sodium channel beta-subunit gene and hypertension in individuals of African ancestry in South Africa.

Nkeh B, Samani NJ, Badenhorst D, Libhaber E, Sareli P, Norton GR, Woodiwiss AJ.

Am J Hypertens. 2003 Oct;16(10):847-52.

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