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Results: 1 to 20 of 42

1.

Three-month stability of the CogState brief battery in healthy older adults, mild cognitive impairment, and Alzheimer's disease: results from the Australian Imaging, Biomarkers, and Lifestyle-rate of change substudy (AIBL-ROCS).

Lim YY, Jaeger J, Harrington K, Ashwood T, Ellis KA, Stöffler A, Szoeke C, Lachovitzki R, Martins RN, Villemagne VL, Bush A, Masters CL, Rowe CC, Ames D, Darby D, Maruff P.

Arch Clin Neuropsychol. 2013 Jun;28(4):320-30. doi: 10.1093/arclin/act021. Epub 2013 Apr 3.

PMID:
23552802
[PubMed - indexed for MEDLINE]
2.

β-amyloid dynamics in human plasma.

Huang Y, Potter R, Sigurdson W, Kasten T, Connors R, Morris JC, Benzinger T, Mintun M, Ashwood T, Ferm M, Budd SL, Bateman RJ.

Arch Neurol. 2012 Dec;69(12):1591-7. doi: 10.1001/archneurol.2012.18107.

PMID:
23229043
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Improving Alzheimer's disease phase II clinical trials.

Greenberg BD, Carrillo MC, Ryan JM, Gold M, Gallagher K, Grundman M, Berman RM, Ashwood T, Siemers ER.

Alzheimers Dement. 2013 Jan;9(1):39-49. doi: 10.1016/j.jalz.2012.02.002. Epub 2012 Nov 16.

PMID:
23164548
[PubMed - indexed for MEDLINE]
4.

Rapid decline in episodic memory in healthy older adults with high amyloid-β.

Lim YY, Pietrzak RH, Ellis KA, Jaeger J, Harrington K, Ashwood T, Szoeke C, Martins RN, Bush AI, Masters CL, Rowe CC, Villemagne VL, Ames D, Darby D, Maruff P.

J Alzheimers Dis. 2013;33(3):675-9. doi: 10.3233/JAD-2012-121516.

PMID:
23001710
[PubMed - indexed for MEDLINE]
5.

Alzheimer's disease therapeutic trials: EU/US Task Force report on recruitment, retention, and methodology.

Vellas B, Hampel H, Rougé-Bugat ME, Grundman M, Andrieu S, Abu-Shakra S, Bateman R, Berman R, Black R, Carrillo M, Donohue M, Mintun M, Morris J, Petersen R, Thomas RG, Suhy J, Schneider L, Seely L, Tariot P, Touchon J, Weiner M, Sampaio C, Aisen P; Task Force Participants.

J Nutr Health Aging. 2012 Apr;16(4):339-45.

PMID:
22499454
[PubMed - indexed for MEDLINE]
6.

Home time is extended in patients with ischemic stroke who receive thrombolytic therapy: a validation study of home time as an outcome measure.

Mishra NK, Shuaib A, Lyden P, Diener HC, Grotta J, Davis S, Davalos A, Ashwood T, Wasiewski W, Lees KR; Stroke Acute Ischemic NXY Treatment I Trialists.

Stroke. 2011 Apr;42(4):1046-50. doi: 10.1161/STROKEAHA.110.601302. Epub 2011 Feb 24.

PMID:
21350199
[PubMed - indexed for MEDLINE]
Free Article
7.

Effects of AZD3480 on cognition in patients with mild-to-moderate Alzheimer's disease: a phase IIb dose-finding study.

Frölich L, Ashwood T, Nilsson J, Eckerwall G; Sirocco Investigators.

J Alzheimers Dis. 2011;24(2):363-74. doi: 10.3233/JAD-2011-101554.

PMID:
21258153
[PubMed - indexed for MEDLINE]
8.

Biomarkers for Alzheimer's disease therapeutic trials.

Hampel H, Wilcock G, Andrieu S, Aisen P, Blennow K, Broich K, Carrillo M, Fox NC, Frisoni GB, Isaac M, Lovestone S, Nordberg A, Prvulovic D, Sampaio C, Scheltens P, Weiner M, Winblad B, Coley N, Vellas B; Oxford Task Force Group.

Prog Neurobiol. 2011 Dec;95(4):579-93. doi: 10.1016/j.pneurobio.2010.11.005. Epub 2010 Dec 2. Review.

PMID:
21130138
[PubMed - indexed for MEDLINE]
9.

NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials.

Diener HC, Lees KR, Lyden P, Grotta J, Davalos A, Davis SM, Shuaib A, Ashwood T, Wasiewski W, Alderfer V, Hårdemark HG, Rodichok L; SAINT I and II Investigators.

Stroke. 2008 Jun;39(6):1751-8. doi: 10.1161/STROKEAHA.107.503334. Epub 2008 Mar 27.

PMID:
18369171
[PubMed - indexed for MEDLINE]
Free Article
10.

The clomethiazole acute stroke study (CLASS): efficacy results in 545 patients classified as total anterior circulation syndrome (TACS).

Wahlgren NG, Bornhov S, Sharma A, Cederin B, Rosolacci T, Ashwood T, Claesson L; CLASS study group.

J Stroke Cerebrovasc Dis. 1999 Jul-Aug;8(4):231-9.

PMID:
17895170
[PubMed]
11.

The clomethiazole acute stroke study in ischemic, hemorrhagic, and t-PA treated stroke: Design of a phase III trial in the united states and canada.

Lyden PD, Ashwood T, Claesson L, Odergren T, Friday GH, Martin-Munley S.

J Stroke Cerebrovasc Dis. 1998 Nov-Dec;7(6):435-41.

PMID:
17895123
[PubMed]
12.

NXY-059 for the treatment of acute ischemic stroke.

Shuaib A, Lees KR, Lyden P, Grotta J, Davalos A, Davis SM, Diener HC, Ashwood T, Wasiewski WW, Emeribe U; SAINT II Trial Investigators.

N Engl J Med. 2007 Aug 9;357(6):562-71.

PMID:
17687131
[PubMed - indexed for MEDLINE]
Free Article
13.

Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial.

Lyden PD, Shuaib A, Lees KR, Davalos A, Davis SM, Diener HC, Grotta JC, Ashwood TJ, Hardemark HG, Svensson HH, Rodichok L, Wasiewski WW, Ahlberg G; CHANT Trial Investigators.

Stroke. 2007 Aug;38(8):2262-9. Epub 2007 Jun 14.

PMID:
17569876
[PubMed - indexed for MEDLINE]
Free Article
14.

Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial.

Lees KR, Davalos A, Davis SM, Diener HC, Grotta J, Lyden P, Shuaib A, Ashwood T, Hardemark HG, Wasiewski W, Emeribe U, Zivin JA; SAINT I Investigators.

Stroke. 2006 Dec;37(12):2970-8. Epub 2006 Oct 26.

PMID:
17068304
[PubMed - indexed for MEDLINE]
Free Article
15.

NXY-059 for acute ischemic stroke.

Lees KR, Zivin JA, Ashwood T, Davalos A, Davis SM, Diener HC, Grotta J, Lyden P, Shuaib A, Hårdemark HG, Wasiewski WW; Stroke-Acute Ischemic NXY Treatment (SAINT I) Trial Investigators.

N Engl J Med. 2006 Feb 9;354(6):588-600.

PMID:
16467546
[PubMed - indexed for MEDLINE]
Free Article
16.

Brain penetration of the novel free radical trapping neuroprotectant NXY-059 in rats subjected to permanent focal ischemia.

Green AR, Lanbeck-Vallén K, Ashwood T, Lundquist S, Lindström Böö E, Jonasson H, Campbell M.

Brain Res. 2006 Feb 9;1072(1):224-6. Epub 2006 Jan 30.

PMID:
16448628
[PubMed - indexed for MEDLINE]
17.

Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers.

Green AR, Ashwood T.

Curr Drug Targets CNS Neurol Disord. 2005 Apr;4(2):109-18. Review.

PMID:
15857295
[PubMed - indexed for MEDLINE]
18.

Factor analysis of the National Institutes of Health Stroke Scale in patients with large strokes.

Lyden P, Claesson L, Havstad S, Ashwood T, Lu M.

Arch Neurol. 2004 Nov;61(11):1677-80.

PMID:
15534178
[PubMed - indexed for MEDLINE]
19.

Early impairment in consciousness predicts mortality after hemispheric ischemic stroke.

Cucchiara BL, Kasner SE, Wolk DA, Lyden PD, Knappertz VA, Ashwood T, Odergren T, Nordlund A; CLASS-I Investigators.

Crit Care Med. 2004 Jan;32(1):241-5.

PMID:
14707586
[PubMed - indexed for MEDLINE]
20.

Nitrones as neuroprotective agents in cerebral ischemia, with particular reference to NXY-059.

Green AR, Ashwood T, Odergren T, Jackson DM.

Pharmacol Ther. 2003 Dec;100(3):195-214. Review.

PMID:
14652110
[PubMed - indexed for MEDLINE]

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