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Results: 12

1.

GnRH-Gemcitabine conjugates for the treatment of androgen-independent prostate cancer: pharmacokinetic enhancements combined with targeted drug delivery.

Karampelas T, Argyros O, Sayyad N, Spyridaki K, Pappas C, Morgan K, Kolios G, Millar RP, Liapakis G, Tzakos AG, Fokas D, Tamvakopoulos C.

Bioconjug Chem. 2014 Apr 16;25(4):813-23. doi: 10.1021/bc500081g. Epub 2014 Apr 3.

PMID:
24661240
[PubMed - in process]
2.

Examination of the effect of increasing the number of intra-disulfide amino functional groups on the performance of small molecule cyclic polyamine disulfide vectors.

Drake CR, Aissaoui A, Argyros O, Thanou M, Steinke JH, Miller AD.

J Control Release. 2013 Oct 10;171(1):81-90. doi: 10.1016/j.jconrel.2013.02.014. Epub 2013 Feb 26.

PMID:
23454113
[PubMed - indexed for MEDLINE]
3.

Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling.

Argyros O, Wong SP, Gowers K, Harbottle RP.

PLoS One. 2012;7(10):e47920. doi: 10.1371/journal.pone.0047920. Epub 2012 Oct 26.

PMID:
23110132
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Vector systems for prenatal gene therapy: principles of non-viral vector design and production.

Wong SP, Argyros O, Harbottle RP.

Methods Mol Biol. 2012;891:133-67. doi: 10.1007/978-1-61779-873-3_7.

PMID:
22648771
[PubMed - indexed for MEDLINE]
5.

Non-viral episomal modification of cells using S/MAR elements.

Argyros O, Wong SP, Harbottle RP.

Expert Opin Biol Ther. 2011 Sep;11(9):1177-91. doi: 10.1517/14712598.2011.582035. Epub 2011 May 9. Review.

PMID:
21548848
[PubMed - indexed for MEDLINE]
6.

Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver.

Argyros O, Wong SP, Fedonidis C, Tolmachov O, Waddington SN, Howe SJ, Niceta M, Coutelle C, Harbottle RP.

J Mol Med (Berl). 2011 May;89(5):515-29. doi: 10.1007/s00109-010-0713-3. Epub 2011 Feb 8.

PMID:
21301798
[PubMed - indexed for MEDLINE]
7.

Systemic gene transfer of polyethylenimine (PEI)-plasmid DNA complexes to neonatal mice.

Wong SP, Argyros O, Howe SJ, Harbottle RP.

J Control Release. 2011 Mar 30;150(3):298-306. doi: 10.1016/j.jconrel.2010.12.010. Epub 2010 Dec 28.

PMID:
21192993
[PubMed - indexed for MEDLINE]
8.

Bioresponsive small molecule polyamines as noncytotoxic alternative to polyethylenimine.

Drake CR, Aissaoui A, Argyros O, Serginson JM, Monnery BD, Thanou M, Steinke JH, Miller AD.

Mol Pharm. 2010 Dec 6;7(6):2040-55. doi: 10.1021/mp9002249. Epub 2010 Oct 7.

PMID:
20929266
[PubMed - indexed for MEDLINE]
9.

Non-viral S/MAR vectors replicate episomally in vivo when provided with a selective advantage.

Wong SP, Argyros O, Coutelle C, Harbottle RP.

Gene Ther. 2011 Jan;18(1):82-7. doi: 10.1038/gt.2010.116. Epub 2010 Aug 26.

PMID:
20739959
[PubMed - indexed for MEDLINE]
10.

pEPito: a significantly improved non-viral episomal expression vector for mammalian cells.

Haase R, Argyros O, Wong SP, Harbottle RP, Lipps HJ, Ogris M, Magnusson T, Vizoso Pinto MG, Haas J, Baiker A.

BMC Biotechnol. 2010 Mar 15;10:20. doi: 10.1186/1472-6750-10-20.

PMID:
20230618
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Strategies for the episomal modification of cells.

Wong SP, Argyros O, Coutelle C, Harbottle RP.

Curr Opin Mol Ther. 2009 Aug;11(4):433-41. Review.

PMID:
19649988
[PubMed - indexed for MEDLINE]
12.

Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.

Argyros O, Wong SP, Niceta M, Waddington SN, Howe SJ, Coutelle C, Miller AD, Harbottle RP.

Gene Ther. 2008 Dec;15(24):1593-605. doi: 10.1038/gt.2008.113. Epub 2008 Jul 17.

PMID:
18633447
[PubMed - indexed for MEDLINE]

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