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Transcriptomics and proteomics show that selenium affects inflammation, cytoskeleton, and cancer pathways in human rectal biopsies.

M├ęplan C, Johnson IT, Polley AC, Cockell S, Bradburn DM, Commane DM, Arasaradnam RP, Mulholland F, Zupanic A, Mathers JC, Hesketh J.

FASEB J. 2016 Apr 21. pii: fj.201600251R. [Epub ahead of print]


A systematic review of the role of DNA methylation on inflammatory genes in ulcerative colitis.

Gould NJ, Davidson KL, Nwokolo CU, Arasaradnam RP.

Epigenomics. 2016 May;8(5):667-84. doi: 10.2217/epi-2016-0006. Epub 2016 Apr 20.


Breathomics--exhaled volatile organic compound analysis to detect hepatic encephalopathy: a pilot study.

Arasaradnam RP, McFarlane M, Ling K, Wurie S, O'Connell N, Nwokolo CU, Bardhan KD, Skinner J, Savage RS, Covington JA.

J Breath Res. 2016 Feb 11;10(1):016012. doi: 10.1088/1752-7155/10/1/016012.


Quantification of 18FDG in the Normal Colon-A First Step in Investigating Whether Its Presence Is a Marker of a Physiological Process.

Bardhan KD, Cullis J, Williams NR, Arasaradnam RP, Wilson AJ.

PLoS One. 2016 Jan 28;11(1):e0147838. doi: 10.1371/journal.pone.0147838. eCollection 2016.


Variation in Gas and Volatile Compound Emissions from Human Urine as It Ages, Measured by an Electronic Nose.

Esfahani S, Sagar NM, Kyrou I, Mozdiak E, O'Connell N, Nwokolo C, Bardhan KD, Arasaradnam RP, Covington JA.

Biosensors (Basel). 2016 Jan 25;6(1). pii: E4. doi: 10.3390/bios6010004.


Non-invasive exhaled volatile organic biomarker analysis to detect inflammatory bowel disease (IBD).

Arasaradnam RP, McFarlane M, Daulton E, Skinner J, O'Connell N, Wurie S, Chambers S, Nwokolo C, Bardhan K, Savage R, Covington J.

Dig Liver Dis. 2016 Feb;48(2):148-53. doi: 10.1016/j.dld.2015.10.013. Epub 2015 Nov 22.


The application of FAIMS gas analysis in medical diagnostics.

Covington JA, van der Schee MP, Edge AS, Boyle B, Savage RS, Arasaradnam RP.

Analyst. 2015 Oct 21;140(20):6775-81. doi: 10.1039/c5an00868a. Review.


Non-invasive distinction of non-alcoholic fatty liver disease using urinary volatile organic compound analysis: early results.

Arasaradnam RP, McFarlane M, Daulton E, Westenbrink E, O'Connell N, Wurie S, Nwokolo CU, Bardhan KD, Savage RS, Covington JA.

J Gastrointestin Liver Dis. 2015 Jun;24(2):197-201. doi: 10.15403/jgld.2014.1121.242.ury.


Field cancerisation in colorectal cancer: a new frontier or pastures past?

Patel A, Tripathi G, Gopalakrishnan K, Williams N, Arasaradnam RP.

World J Gastroenterol. 2015 Apr 7;21(13):3763-72. doi: 10.3748/wjg.v21.i13.3763. Review.


The interplay of the gut microbiome, bile acids, and volatile organic compounds.

Sagar NM, Cree IA, Covington JA, Arasaradnam RP.

Gastroenterol Res Pract. 2015;2015:398585. doi: 10.1155/2015/398585. Epub 2015 Mar 3. Review.


Utility of faecal calprotectin in inflammatory bowel disease (IBD): what cut-offs should we apply?

Dhaliwal A, Zeino Z, Tomkins C, Cheung M, Nwokolo C, Smith S, Harmston C, Arasaradnam RP.

Frontline Gastroenterol. 2015 Jan;6(1):14-19. Epub 2014 Mar 17.


Development and application of a new electronic nose instrument for the detection of colorectal cancer.

Westenbrink E, Arasaradnam RP, O'Connell N, Bailey C, Nwokolo C, Bardhan KD, Covington JA.

Biosens Bioelectron. 2015 May 15;67:733-8. doi: 10.1016/j.bios.2014.10.044. Epub 2014 Oct 23.


Differentiating coeliac disease from irritable bowel syndrome by urinary volatile organic compound analysis--a pilot study.

Arasaradnam RP, Westenbrink E, McFarlane MJ, Harbord R, Chambers S, O'Connell N, Bailey C, Nwokolo CU, Bardhan KD, Savage R, Covington JA.

PLoS One. 2014 Oct 16;9(10):e107312. doi: 10.1371/journal.pone.0107312. eCollection 2014.


Detection of colorectal cancer (CRC) by urinary volatile organic compound analysis.

Arasaradnam RP, McFarlane MJ, Ryan-Fisher C, Westenbrink E, Hodges P, Thomas MG, Chambers S, O'Connell N, Bailey C, Harmston C, Nwokolo CU, Bardhan KD, Covington JA.

PLoS One. 2014 Sep 30;9(9):e108750. doi: 10.1371/journal.pone.0108750. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0118975. Hodges, Paula [corrected to Hodges, Phoebe].


Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing.

Greaves LC, Nooteboom M, Elson JL, Tuppen HA, Taylor GA, Commane DM, Arasaradnam RP, Khrapko K, Taylor RW, Kirkwood TB, Mathers JC, Turnbull DM.

PLoS Genet. 2014 Sep 18;10(9):e1004620. doi: 10.1371/journal.pgen.1004620. eCollection 2014 Sep.


Editorial: Metabolomic analysis of breath volatile organic compounds--a new scent for inflammatory bowel disease.

Arasaradnam RP, Covington J, Nwokolo CU.

Aliment Pharmacol Ther. 2014 Sep;40(6):732-3. doi: 10.1111/apt.12901. No abstract available.


Review article: next generation diagnostic modalities in gastroenterology--gas phase volatile compound biomarker detection.

Arasaradnam RP, Covington JA, Harmston C, Nwokolo CU.

Aliment Pharmacol Ther. 2014 Apr;39(8):780-9. doi: 10.1111/apt.12657. Epub 2014 Feb 20. Review.


Nasogastric feeding tubes - algorithm for correct placement.

Das I, Lin D, Muthalagappan S, Colby J, Trautner E, Wyre N, Wellings R, Nwokolo CU, Arasaradnam RP.

Clin Med (Lond). 2013 Oct;13(5):527-8. doi: 10.7861/clinmedicine.13-5-527. No abstract available.


Application of a novel tool for diagnosing bile acid diarrhoea.

Covington JA, Westenbrink EW, Ouaret N, Harbord R, Bailey C, O'Connell N, Cullis J, Williams N, Nwokolo CU, Bardhan KD, Arasaradnam RP.

Sensors (Basel). 2013 Sep 6;13(9):11899-912. doi: 10.3390/s130911899.


A novel tool for noninvasive diagnosis and tracking of patients with inflammatory bowel disease.

Arasaradnam RP, Ouaret N, Thomas MG, Quraishi N, Heatherington E, Nwokolo CU, Bardhan KD, Covington JA.

Inflamm Bowel Dis. 2013 Apr;19(5):999-1003. doi: 10.1097/MIB.0b013e3182802b26.

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