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Results: 1 to 20 of 69

1.

Bongkrekic acid as a selective activator of the peroxisome proliferator-activated receptor γ (PPARγ) isoform.

Okazaki H, Takeda S, Ikeda E, Fukunishi Y, Ishii H, Taniguchi A, Tokuyasu M, Himeno T, Kakizoe K, Matsumoto K, Shindo M, Aramaki H.

J Toxicol Sci. 2015;40(2):223-33. doi: 10.2131/jts.40.223.

2.

Δ(9)-THC modulation of fatty acid 2-hydroxylase (FA2H) gene expression: possible involvement of induced levels of PPARα in MDA-MB-231 breast cancer cells.

Takeda S, Ikeda E, Su S, Harada M, Okazaki H, Yoshioka Y, Nishimura H, Ishii H, Kakizoe K, Taniguchi A, Tokuyasu M, Himeno T, Watanabe K, Omiecinski CJ, Aramaki H.

Toxicology. 2014 Dec 4;326:18-24. doi: 10.1016/j.tox.2014.09.011. Epub 2014 Oct 5.

3.

Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells.

Takeda S, Okazaki H, Ikeda E, Abe S, Yoshioka Y, Watanabe K, Aramaki H.

J Toxicol Sci. 2014;39(5):711-6.

4.
5.

Xanthocidin derivatives as topoisomerase IIα enzymatic inhibitors.

Takeda S, Yaji K, Matsumoto K, Amamoto T, Shindo M, Aramaki H.

Biol Pharm Bull. 2014;37(2):331-4.

6.

(-)-Xanthatin induces the prolonged expression of c-Fos through an N-acetyl-L-cysteine (NAC)-sensitive mechanism in human breast cancer MDA-MB-231 cells.

Takeda S, Nishimura H, Koyachi K, Matsumoto K, Yoshida K, Okamoto Y, Amamoto T, Shindo M, Aramaki H.

J Toxicol Sci. 2013;38(4):547-57.

7.

Δ(9)-Tetrahydrocannabinol disrupts estrogen-signaling through up-regulation of estrogen receptor β (ERβ).

Takeda S, Yoshida K, Nishimura H, Harada M, Okajima S, Miyoshi H, Okamoto Y, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.

Chem Res Toxicol. 2013 Jul 15;26(7):1073-9. doi: 10.1021/tx4000446. Epub 2013 Jun 11.

8.

Induction of the fatty acid 2-hydroxylase (FA2H) gene by Δ(9)-tetrahydrocannabinol in human breast cancer cells.

Takeda S, Harada M, Su S, Okajima S, Miyoshi H, Yoshida K, Nishimura H, Okamoto Y, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.

J Toxicol Sci. 2013;38(2):305-8.

9.

(-)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: role of topoisomerase IIα inhibition and reactive oxygen species.

Takeda S, Noguchi M, Matsuo K, Yamaguchi Y, Kudo T, Nishimura H, Okamoto Y, Amamoto T, Shindo M, Omiecinski CJ, Aramaki H.

Toxicology. 2013 Mar 8;305:1-9. doi: 10.1016/j.tox.2012.12.019. Epub 2013 Jan 8.

10.

Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.

Taygerly JP, McGee LR, Rubenstein SM, Houze JB, Cushing TD, Li Y, Motani A, Chen JL, Frankmoelle W, Ye G, Learned MR, Jaen J, Miao S, Timmermans PB, Thoolen M, Kearney P, Flygare J, Beckmann H, Weiszmann J, Lindstrom M, Walker N, Liu J, Biermann D, Wang Z, Hagiwara A, Iida T, Aramaki H, Kitao Y, Shinkai H, Furukawa N, Nishiu J, Nakamura M.

Bioorg Med Chem. 2013 Feb 15;21(4):979-92. doi: 10.1016/j.bmc.2012.11.058. Epub 2012 Dec 10.

PMID:
23294830
11.

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.

Takeda S, Okajima S, Miyoshi H, Yoshida K, Okamoto Y, Okada T, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.

Toxicol Lett. 2012 Nov 15;214(3):314-9. doi: 10.1016/j.toxlet.2012.08.029. Epub 2012 Sep 8.

12.

The correlation between motor impairments and event-related desynchronization during motor imagery in ALS patients.

Kasahara T, Terasaki K, Ogawa Y, Ushiba J, Aramaki H, Masakado Y.

BMC Neurosci. 2012 Jun 15;13:66. doi: 10.1186/1471-2202-13-66.

13.

Formation of repressor-inducer-operator ternary complex: negative cooperativity of d-camphor binding to CamR.

Aramaki H, Kabata H, Takeda S, Itou H, Nakayama H, Shimamoto N.

Genes Cells. 2011 Dec;16(12):1200-7. doi: 10.1111/j.1365-2443.2011.01563.x. Epub 2011 Nov 17.

PMID:
22093184
14.

Cannabidiol-2',6'-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro.

Takeda S, Hirayama A, Urata S, Mano N, Fukagawa K, Imamura M, Irii A, Kitajima S, Masuyama T, Nomiyama M, Tatei S, Tomita S, Kudo T, Noguchi M, Yamaguchi Y, Okamoto Y, Amamoto T, Fukunishi Y, Watanabe K, Omiecinski CJ, Aramaki H.

Biol Pharm Bull. 2011;34(8):1252-6.

15.

(--)-Xanthatin selectively induces GADD45γ and stimulates caspase-independent cell death in human breast cancer MDA-MB-231 cells.

Takeda S, Matsuo K, Yaji K, Okajima-Miyazaki S, Harada M, Miyoshi H, Okamoto Y, Amamoto T, Shindo M, Omiecinski CJ, Aramaki H.

Chem Res Toxicol. 2011 Jun 20;24(6):855-65. doi: 10.1021/tx200046s. Epub 2011 May 13.

16.

Δ9-tetrahydrocannabinol and its major metabolite Δ9-tetrahydrocannabinol-11-oic acid as 15-lipoxygenase inhibitors.

Takeda S, Jiang R, Aramaki H, Imoto M, Toda A, Eyanagi R, Amamoto T, Yamamoto I, Watanabe K.

J Pharm Sci. 2011 Mar;100(3):1206-11. doi: 10.1002/jps.22354. Epub 2010 Oct 1.

PMID:
20891010
17.

Quinolone carboxylic acids as a novel monoketo acid class of human immunodeficiency virus type 1 integrase inhibitors.

Sato M, Kawakami H, Motomura T, Aramaki H, Matsuda T, Yamashita M, Ito Y, Matsuzaki Y, Yamataka K, Ikeda S, Shinkai H.

J Med Chem. 2009 Aug 13;52(15):4869-82. doi: 10.1021/jm900460z.

PMID:
19719237
18.

Role of glucocorticoid receptor in the regulation of cellular sensitivity to irinotecan hydrochloride.

Akagi T, Fukagawa T, Kage Y, To H, Matsunaga N, Koyanagi S, Uchida A, Fujii A, Iba H, Ikemura T, Aramaki H, Higuchi S, Ohdo S.

J Pharmacol Sci. 2009 Feb;109(2):265-74.

19.

Dosing schedule-dependent change in the disruptive effects of interferon-alpha on the circadian clock function.

Shinohara A, Koyanagi S, Hamdan AM, Matsunaga N, Aramaki H, Ohdo S.

Life Sci. 2008 Oct 10;83(15-16):574-80. doi: 10.1016/j.lfs.2008.08.005. Epub 2008 Aug 24.

PMID:
18775731
20.

Transcription regulation by feast/famine regulatory proteins, FFRPs, in archaea and eubacteria.

Kawashima T, Aramaki H, Oyamada T, Makino K, Yamada M, Okamura H, Yokoyama K, Ishijima SA, Suzuki M.

Biol Pharm Bull. 2008 Feb;31(2):173-86.

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