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Results: 1 to 20 of 65

1.

Xanthocidin derivatives as topoisomerase IIα enzymatic inhibitors.

Takeda S, Yaji K, Matsumoto K, Amamoto T, Shindo M, Aramaki H.

Biol Pharm Bull. 2014;37(2):331-4.

PMID:
24492731
[PubMed - in process]
Free Article
2.

(-)-Xanthatin induces the prolonged expression of c-Fos through an N-acetyl-L-cysteine (NAC)-sensitive mechanism in human breast cancer MDA-MB-231 cells.

Takeda S, Nishimura H, Koyachi K, Matsumoto K, Yoshida K, Okamoto Y, Amamoto T, Shindo M, Aramaki H.

J Toxicol Sci. 2013;38(4):547-57.

PMID:
23824011
[PubMed - indexed for MEDLINE]
Free Article
3.

Δ(9)-tetrahydrocannabinol disrupts estrogen-signaling through up-regulation of estrogen receptor β (ERβ).

Takeda S, Yoshida K, Nishimura H, Harada M, Okajima S, Miyoshi H, Okamoto Y, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.

Chem Res Toxicol. 2013 Jul 15;26(7):1073-9. doi: 10.1021/tx4000446. Epub 2013 Jun 11.

PMID:
23718638
[PubMed - in process]
Free PMC Article
4.

Induction of the fatty acid 2-hydroxylase (FA2H) gene by Δ(9)-tetrahydrocannabinol in human breast cancer cells.

Takeda S, Harada M, Su S, Okajima S, Miyoshi H, Yoshida K, Nishimura H, Okamoto Y, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.

J Toxicol Sci. 2013;38(2):305-8.

PMID:
23535410
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

(-)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: role of topoisomerase IIα inhibition and reactive oxygen species.

Takeda S, Noguchi M, Matsuo K, Yamaguchi Y, Kudo T, Nishimura H, Okamoto Y, Amamoto T, Shindo M, Omiecinski CJ, Aramaki H.

Toxicology. 2013 Mar 8;305:1-9. doi: 10.1016/j.tox.2012.12.019. Epub 2013 Jan 8.

PMID:
23313378
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.

Taygerly JP, McGee LR, Rubenstein SM, Houze JB, Cushing TD, Li Y, Motani A, Chen JL, Frankmoelle W, Ye G, Learned MR, Jaen J, Miao S, Timmermans PB, Thoolen M, Kearney P, Flygare J, Beckmann H, Weiszmann J, Lindstrom M, Walker N, Liu J, Biermann D, Wang Z, Hagiwara A, Iida T, Aramaki H, Kitao Y, Shinkai H, Furukawa N, Nishiu J, Nakamura M.

Bioorg Med Chem. 2013 Feb 15;21(4):979-92. doi: 10.1016/j.bmc.2012.11.058. Epub 2012 Dec 10.

PMID:
23294830
[PubMed - indexed for MEDLINE]
7.

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.

Takeda S, Okajima S, Miyoshi H, Yoshida K, Okamoto Y, Okada T, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.

Toxicol Lett. 2012 Nov 15;214(3):314-9. doi: 10.1016/j.toxlet.2012.08.029. Epub 2012 Sep 8.

PMID:
22963825
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The correlation between motor impairments and event-related desynchronization during motor imagery in ALS patients.

Kasahara T, Terasaki K, Ogawa Y, Ushiba J, Aramaki H, Masakado Y.

BMC Neurosci. 2012 Jun 15;13:66. doi: 10.1186/1471-2202-13-66.

PMID:
22703383
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Formation of repressor-inducer-operator ternary complex: negative cooperativity of d-camphor binding to CamR.

Aramaki H, Kabata H, Takeda S, Itou H, Nakayama H, Shimamoto N.

Genes Cells. 2011 Dec;16(12):1200-7. doi: 10.1111/j.1365-2443.2011.01563.x. Epub 2011 Nov 17.

PMID:
22093184
[PubMed - indexed for MEDLINE]
10.

Cannabidiol-2',6'-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro.

Takeda S, Hirayama A, Urata S, Mano N, Fukagawa K, Imamura M, Irii A, Kitajima S, Masuyama T, Nomiyama M, Tatei S, Tomita S, Kudo T, Noguchi M, Yamaguchi Y, Okamoto Y, Amamoto T, Fukunishi Y, Watanabe K, Omiecinski CJ, Aramaki H.

Biol Pharm Bull. 2011;34(8):1252-6.

PMID:
21804214
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

(--)-Xanthatin selectively induces GADD45γ and stimulates caspase-independent cell death in human breast cancer MDA-MB-231 cells.

Takeda S, Matsuo K, Yaji K, Okajima-Miyazaki S, Harada M, Miyoshi H, Okamoto Y, Amamoto T, Shindo M, Omiecinski CJ, Aramaki H.

Chem Res Toxicol. 2011 Jun 20;24(6):855-65. doi: 10.1021/tx200046s. Epub 2011 May 13.

PMID:
21568272
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Δ9-tetrahydrocannabinol and its major metabolite Δ9-tetrahydrocannabinol-11-oic acid as 15-lipoxygenase inhibitors.

Takeda S, Jiang R, Aramaki H, Imoto M, Toda A, Eyanagi R, Amamoto T, Yamamoto I, Watanabe K.

J Pharm Sci. 2011 Mar;100(3):1206-11. doi: 10.1002/jps.22354. Epub 2010 Oct 1.

PMID:
20891010
[PubMed - indexed for MEDLINE]
13.

Quinolone carboxylic acids as a novel monoketo acid class of human immunodeficiency virus type 1 integrase inhibitors.

Sato M, Kawakami H, Motomura T, Aramaki H, Matsuda T, Yamashita M, Ito Y, Matsuzaki Y, Yamataka K, Ikeda S, Shinkai H.

J Med Chem. 2009 Aug 13;52(15):4869-82. doi: 10.1021/jm900460z.

PMID:
19719237
[PubMed - indexed for MEDLINE]
14.

Role of glucocorticoid receptor in the regulation of cellular sensitivity to irinotecan hydrochloride.

Akagi T, Fukagawa T, Kage Y, To H, Matsunaga N, Koyanagi S, Uchida A, Fujii A, Iba H, Ikemura T, Aramaki H, Higuchi S, Ohdo S.

J Pharmacol Sci. 2009 Feb;109(2):265-74.

PMID:
19234367
[PubMed - indexed for MEDLINE]
Free Article
15.

Dosing schedule-dependent change in the disruptive effects of interferon-alpha on the circadian clock function.

Shinohara A, Koyanagi S, Hamdan AM, Matsunaga N, Aramaki H, Ohdo S.

Life Sci. 2008 Oct 10;83(15-16):574-80. doi: 10.1016/j.lfs.2008.08.005. Epub 2008 Aug 24.

PMID:
18775731
[PubMed - indexed for MEDLINE]
16.

Transcription regulation by feast/famine regulatory proteins, FFRPs, in archaea and eubacteria.

Kawashima T, Aramaki H, Oyamada T, Makino K, Yamada M, Okamura H, Yokoyama K, Ishijima SA, Suzuki M.

Biol Pharm Bull. 2008 Feb;31(2):173-86.

PMID:
18239270
[PubMed - indexed for MEDLINE]
Free Article
17.

Effect of L-serine on the biosynthesis of aromatic amino acids in Escherichia coli.

Tazuya-Murayama K, Aramaki H, Mishima M, Saito K, Ishida S, Yamada K.

J Nutr Sci Vitaminol (Tokyo). 2006 Aug;52(4):256-60.

PMID:
17087051
[PubMed - indexed for MEDLINE]
Free Article
18.

Basis for dosing time-dependent change in the anti-tumor effect of imatinib in mice.

Nakagawa H, Takiguchi T, Nakamura M, Furuyama A, Koyanagi S, Aramaki H, Higuchi S, Ohdo S.

Biochem Pharmacol. 2006 Nov 15;72(10):1237-45. Epub 2006 Sep 14.

PMID:
16973134
[PubMed - indexed for MEDLINE]
19.

Transcriptional analysis of the Pseudomonas aeruginosa toxA regulatory gene ptxR.

Colmer-Hamood JA, Aramaki H, Gaines JM, Hamood AN.

Can J Microbiol. 2006 Apr;52(4):343-56.

PMID:
16699585
[PubMed - indexed for MEDLINE]
20.

Expression, crystallization and preliminary diffraction studies of the Pseudomonas putida cytochrome P450cam operon repressor CamR.

Maenaka K, Fukushi K, Aramaki H, Shirakihara Y.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Aug 1;61(Pt 8):796-8. Epub 2005 Jul 30.

PMID:
16511161
[PubMed - indexed for MEDLINE]
Free PMC Article

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