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Items: 20


Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virions.

Bhardwaj A, Sankhala RS, Olia AS, Brooke D, Casjens SR, Taylor DJ, Prevelige PE Jr, Cingolani G.

J Biol Chem. 2015 Nov 16. pii: jbc.M115.696260. [Epub ahead of print]


Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.

Lokareddy RK, Hapsari RA, van Rheenen M, Pumroy RA, Bhardwaj A, Steen A, Veenhoff LM, Cingolani G.

Structure. 2015 Jul 7;23(7):1305-16. doi: 10.1016/j.str.2015.04.017. Epub 2015 Jun 4.


Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases.

Komolov KE, Bhardwaj A, Benovic JL.

J Biol Chem. 2015 Aug 21;290(34):20629-47. doi: 10.1074/jbc.M115.647297. Epub 2015 Jun 1.


An α-helical core encodes the dual functions of the chlamydial protein IncA.

Ronzone E, Wesolowski J, Bauler LD, Bhardwaj A, Hackstadt T, Paumet F.

J Biol Chem. 2014 Nov 28;289(48):33469-80. doi: 10.1074/jbc.M114.592063. Epub 2014 Oct 16.


Architecture of viral genome-delivery molecular machines.

Bhardwaj A, Olia AS, Cingolani G.

Curr Opin Struct Biol. 2014 Apr;25:1-8. doi: 10.1016/ Epub 2013 Nov 15. Review.


Exploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallography.

Bhardwaj A, Casjens SR, Cingolani G.

Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):342-53. doi: 10.1107/S1399004713027685. Epub 2014 Jan 29.


The tip of the tail needle affects the rate of DNA delivery by bacteriophage P22.

Leavitt JC, Gogokhia L, Gilcrease EB, Bhardwaj A, Cingolani G, Casjens SR.

PLoS One. 2013 Aug 12;8(8):e70936. doi: 10.1371/journal.pone.0070936. eCollection 2013.


Engineering and characterization of the chimeric antibody that targets the C-terminal telopeptide of the α2 chain of human collagen I: a next step in the quest to reduce localized fibrosis.

Fertala J, Steplewski A, Kostas J, Beredjiklian P, Williams G, Arnold W, Abboud J, Bhardwaj A, Hou C, Fertala A.

Connect Tissue Res. 2013;54(3):187-96. doi: 10.3109/03008207.2013.778839. Epub 2013 Apr 15.


Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.

Lokareddy RK, Bhardwaj A, Cingolani G.

Biochemistry. 2013 Feb 5;52(5):938-48. doi: 10.1021/bi301476m. Epub 2013 Jan 18.


Small terminase couples viral DNA binding to genome-packaging ATPase activity.

Roy A, Bhardwaj A, Datta P, Lander GC, Cingolani G.

Structure. 2012 Aug 8;20(8):1403-13. doi: 10.1016/j.str.2012.05.014. Epub 2012 Jul 5.


Atomic structure of bacteriophage Sf6 tail needle knob.

Bhardwaj A, Molineux IJ, Casjens SR, Cingolani G.

J Biol Chem. 2011 Sep 2;286(35):30867-77. doi: 10.1074/jbc.M111.260877. Epub 2011 Jun 25.


A minimal nuclear localization signal (NLS) in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin alpha1.

Lott K, Bhardwaj A, Sims PJ, Cingolani G.

J Biol Chem. 2011 Aug 12;286(32):28160-9. doi: 10.1074/jbc.M111.228007. Epub 2011 Jun 20.


Crystallization of the nonameric small terminase subunit of bacteriophage P22.

Roy A, Bhardwaj A, Cingolani G.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jan 1;67(Pt 1):104-10. doi: 10.1107/S174430911004697X. Epub 2010 Dec 23.


Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta.

Bhardwaj A, Cingolani G.

Biochemistry. 2010 Jun 22;49(24):5042-7. doi: 10.1021/bi100292y.


The importin beta binding domain modulates the avidity of importin beta for the nuclear pore complex.

Lott K, Bhardwaj A, Mitrousis G, Pante N, Cingolani G.

J Biol Chem. 2010 Apr 30;285(18):13769-80. doi: 10.1074/jbc.M109.095760. Epub 2010 Mar 1.


An evolutionarily conserved family of virion tail needles related to bacteriophage P22 gp26: correlation between structural stability and length of the alpha-helical trimeric coiled coil.

Bhardwaj A, Walker-Kopp N, Casjens SR, Cingolani G.

J Mol Biol. 2009 Aug 7;391(1):227-45. doi: 10.1016/j.jmb.2009.05.069. Epub 2009 May 29.


Foldon-guided self-assembly of ultra-stable protein fibers.

Bhardwaj A, Walker-Kopp N, Wilkens S, Cingolani G.

Protein Sci. 2008 Sep;17(9):1475-85. doi: 10.1110/ps.036111.108. Epub 2008 Jun 5.


Role of gene 10 protein in the hierarchical assembly of the bacteriophage P22 portal vertex structure.

Olia AS, Bhardwaj A, Joss L, Casjens S, Cingolani G.

Biochemistry. 2007 Jul 31;46(30):8776-84. Epub 2007 Jul 10.


Domain organization and polarity of tail needle GP26 in the portal vertex structure of bacteriophage P22.

Bhardwaj A, Olia AS, Walker-Kopp N, Cingolani G.

J Mol Biol. 2007 Aug 10;371(2):374-87. Epub 2007 May 24.


Conformation and stability of the Streptococcus pyogenes pSM19035-encoded site-specific beta recombinase, and identification of a folding intermediate.

Bhardwaj A, Welfle K, Misselwitz R, Ayora S, Alonso JC, Welfle H.

Biol Chem. 2006 May;387(5):525-33.

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