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Items: 7

1.

CNS Anticancer Drug Discovery and Development Conference White Paper.

Levin VA, Tonge PJ, Gallo JM, Birtwistle MR, Dar AC, Iavarone A, Paddison PJ, Heffron TP, Elmquist WF, Lachowicz JE, Johnson TW, White FM, Sul J, Smith QR, Shen W, Sarkaria JN, Samala R, Wen PY, Berry DA, Petter RC.

Neuro Oncol. 2015 Nov;17 Suppl 6:vi1-26. doi: 10.1093/neuonc/nov169.

PMID:
26403167
2.

ANG4043, a novel brain-penetrant peptide-mAb conjugate, is efficacious against HER2-positive intracranial tumors in mice.

Regina A, Demeule M, Tripathy S, Lord-Dufour S, Currie JC, Iddir M, Annabi B, Castaigne JP, Lachowicz JE.

Mol Cancer Ther. 2015 Jan;14(1):129-40. doi: 10.1158/1535-7163.MCT-14-0399. Epub 2014 Dec 9.

3.

New Angiopep-modified doxorubicin (ANG1007) and etoposide (ANG1009) chemotherapeutics with increased brain penetration.

Ché C, Yang G, Thiot C, Lacoste MC, Currie JC, Demeule M, Régina A, Béliveau R, Castaigne JP.

J Med Chem. 2010 Apr 8;53(7):2814-24. doi: 10.1021/jm9016637.

PMID:
20210346
4.

Transport characteristics of a novel peptide platform for CNS therapeutics.

Bertrand Y, Currie JC, Demeule M, Régina A, Ché C, Abulrob A, Fatehi D, Sartelet H, Gabathuler R, Castaigne JP, Stanimirovic D, Béliveau R.

J Cell Mol Med. 2010 Dec;14(12):2827-39. doi: 10.1111/j.1582-4934.2009.00930.x.

5.

Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases.

Gabathuler R.

Neurobiol Dis. 2010 Jan;37(1):48-57. doi: 10.1016/j.nbd.2009.07.028. Epub 2009 Aug 5. Review.

PMID:
19664710
6.

Blood-brain barrier transport of drugs for the treatment of brain diseases.

Gabathuler R.

CNS Neurol Disord Drug Targets. 2009 Jun;8(3):195-204. Review.

PMID:
19601817
7.

Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2.

Demeule M, Currie JC, Bertrand Y, Ché C, Nguyen T, Régina A, Gabathuler R, Castaigne JP, Béliveau R.

J Neurochem. 2008 Aug;106(4):1534-44. doi: 10.1111/j.1471-4159.2008.05492.x. Epub 2008 May 19.

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