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Ammonia produces pathological changes in human hepatic stellate cells and is a target for therapy of portal hypertension.

Jalan R, De Chiara F, Balasubramaniyan V, Andreola F, Khetan V, Malago M, Pinzani M, Mookerjee RP, Rombouts K.

J Hepatol. 2016 Apr;64(4):823-33. doi: 10.1016/j.jhep.2015.11.019. Epub 2015 Dec 2.


In vitro evaluation of the wound healing activity of Drypetes klainei stem bark extracts.

Brusotti G, Andreola F, Sferrazza G, Grisoli P, Merelli A, Robustelli della Cuna FS, Calleri E, Nicotera G, Pierimarchi P, Serafino A.

J Ethnopharmacol. 2015 Dec 4;175:412-21. doi: 10.1016/j.jep.2015.09.015. Epub 2015 Sep 25.


Thymosin α1 modifies podosome architecture and promptly stimulates the expression of podosomal markers in mature macrophages.

Serafino A, Andreola F, Pittaluga E, Krasnowska EK, Nicotera G, Sferrazza G, Sinibaldi Vallebona P, Pierimarchi P, Garaci E.

Expert Opin Biol Ther. 2015;15 Suppl 1:S101-16. doi: 10.1517/14712598.2015.1024221. Epub 2015 Jun 22.


Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure.

Baker LA, Lee KC, Palacios Jimenez C, Alibhai H, Chang YM, Leckie PJ, Mookerjee RP, Davies NA, Andreola F, Jalan R.

PLoS One. 2015 May 27;10(5):e0128076. doi: 10.1371/journal.pone.0128076. eCollection 2015.


Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study.

Lee KC, Baker LA, Stanzani G, Alibhai H, Chang YM, Jimenez Palacios C, Leckie PJ, Giordano P, Priestnall SL, Antoine DJ, Jenkins RE, Goldring CE, Park BK, Andreola F, Agarwal B, Mookerjee RP, Davies NA, Jalan R.

J Hepatol. 2015 Sep;63(3):634-42. doi: 10.1016/j.jhep.2015.04.020. Epub 2015 May 1.


Mechanism of cell death in acute-on-chronic liver failure: a clinico-pathologic-biomarker study.

Adebayo D, Morabito V, Andreola F, Pieri G, Luong TV, Dhillon A, Mookerjee R, Jalan R.

Liver Int. 2015 Dec;35(12):2564-74. doi: 10.1111/liv.12850. Epub 2015 May 11.


Immunomodulatory and antioxidant function of albumin stabilises the endothelium and improves survival in a rodent model of chronic liver failure.

Garcia-Martinez R, Andreola F, Mehta G, Poulton K, Oria M, Jover M, Soeda J, Macnaughtan J, De Chiara F, Habtesion A, Mookerjee RP, Davies N, Jalan R.

J Hepatol. 2015 Apr;62(4):799-806. doi: 10.1016/j.jhep.2014.10.031. Epub 2014 Oct 30.


Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma.

Mohamed FE, Al-Jehani RM, Minogue SS, Andreola F, Winstanley A, Olde Damink SW, Habtesion A, Malagó M, Davies N, Luong TV, Dhillon AP, Mookerjee RP, Dhar DK, Jalan R.

Liver Int. 2015 Mar;35(3):1063-76. doi: 10.1111/liv.12626. Epub 2014 Jul 30.


WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer.

Serafino A, Moroni N, Zonfrillo M, Andreola F, Mercuri L, Nicotera G, Nunziata J, Ricci R, Antinori A, Rasi G, Pierimarchi P.

Oncotarget. 2014 Feb 28;5(4):978-92.


Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling.

Sandanayake NS, Camuzeaux S, Sinclair J, Blyuss O, Andreola F, Chapman MH, Webster GJ, Smith RC, Timms JF, Pereira SP.

BMC Clin Pathol. 2014 Feb 4;14(1):7. doi: 10.1186/1472-6890-14-7.


Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression.

Gualtieri A, Andreola F, Sciamanna I, Sinibaldi-Vallebona P, Serafino A, Spadafora C.

Oncotarget. 2013 Nov;4(11):1882-93.


Thymosin α1 activates complement receptor-mediated phagocytosis in human monocyte-derived macrophages.

Serafino A, Pica F, Andreola F, Gaziano R, Moroni N, Moroni G, Zonfrillo M, Pierimarchi P, Sinibaldi-Vallebona P, Garaci E.

J Innate Immun. 2014;6(1):72-88. doi: 10.1159/000351587. Epub 2013 Jun 22.


Management of agricultural biomass wastes: preliminary study on characterization and valorisation in clay matrix bricks.

Barbieri L, Andreola F, Lancellotti I, Taurino R.

Waste Manag. 2013 Nov;33(11):2307-15. doi: 10.1016/j.wasman.2013.03.014. Epub 2013 Apr 18.


Thymosin α1 as a stimulatory agent of innate cell-mediated immune response.

Serafino A, Pierimarchi P, Pica F, Andreola F, Gaziano R, Moroni N, Zonfrillo M, Sinibaldi-Vallebona P, Garaci E.

Ann N Y Acad Sci. 2012 Oct;1270:13-20. doi: 10.1111/j.1749-6632.2012.06707.x. Review.


Pyruvate kinase M2 is a novel diagnostic marker and predicts tumor progression in human biliary tract cancer.

Dhar DK, Olde Damink SW, Brindley JH, Godfrey A, Chapman MH, Sandanayake NS, Andreola F, Mazurek S, Hasan T, Malago M, Pereira SP.

Cancer. 2013 Feb 1;119(3):575-85. doi: 10.1002/cncr.27611. Epub 2012 Aug 1.


Anti-proliferative effect of atrial natriuretic peptide on colorectal cancer cells: evidence for an Akt-mediated cross-talk between NHE-1 activity and Wnt/β-catenin signaling.

Serafino A, Moroni N, Psaila R, Zonfrillo M, Andreola F, Wannenes F, Mercuri L, Rasi G, Pierimarchi P.

Biochim Biophys Acta. 2012 Jun;1822(6):1004-18. doi: 10.1016/j.bbadis.2012.02.016. Epub 2012 Feb 25.


Circulating CYFRA 21-1 is a Specific Diagnostic and Prognostic Biomarker in Biliary Tract Cancer.

Chapman MH, Sandanayake NS, Andreola F, Dhar DK, Webster GJ, Dooley JS, Pereira SP.

J Clin Exp Hepatol. 2011 Jun;1(1):6-12.


Whole genome RNA expression profiling of endoscopic biliary brushings provides data suitable for biomarker discovery in cholangiocarcinoma.

Chapman MH, Tidswell R, Dooley JS, Sandanayake NS, Cerec V, Deheragoda M, Lee AJ, Swanton C, Andreola F, Pereira SP.

J Hepatol. 2012 Apr;56(4):877-85. doi: 10.1016/j.jhep.2011.10.022. Epub 2011 Dec 13.


A combination of serum leucine-rich α-2-glycoprotein 1, CA19-9 and interleukin-6 differentiate biliary tract cancer from benign biliary strictures.

Sandanayake NS, Sinclair J, Andreola F, Chapman MH, Xue A, Webster GJ, Clarkson A, Gill A, Norton ID, Smith RC, Timms JF, Pereira SP.

Br J Cancer. 2011 Oct 25;105(9):1370-8. doi: 10.1038/bjc.2011.376. Epub 2011 Oct 4.


Highly electroconductive multiwalled carbon nanotubes as potentially useful tools for modulating calcium balancing in biological environments.

Serafino A, Togna AR, Togna GI, Lisi A, Ledda M, Grimaldi S, Russier J, Andreola F, Monthioux M, Béguin F, Marcaccio M, Rapino S, Paolucci F, Fiorito S.

Nanomedicine. 2012 Apr;8(3):299-307. doi: 10.1016/j.nano.2011.06.018. Epub 2011 Jun 30.

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