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Results: 7

1.

Multivalent Antiviral XTEN-Peptide Conjugates with Long in Vivo Half-Life and Enhanced Solubility.

Ding S, Song M, Sim BC, Gu C, Podust VN, Wang CW, McLaughlin B, Shah TP, Lax R, Gast R, Sharan R, Vasek A, Hartman MA, Deniston C, Srinivas P, Schellenberger V.

Bioconjug Chem. 2014 Jun 23. [Epub ahead of print]

PMID:
24932887
[PubMed - as supplied by publisher]
2.

Extension of in vivo half-life of biologically active peptides via chemical conjugation to XTEN protein polymer.

Podust VN, Sim BC, Kothari D, Henthorn L, Gu C, Wang CW, McLaughlin B, Schellenberger V.

Protein Eng Des Sel. 2013 Nov;26(11):743-53. doi: 10.1093/protein/gzt048. Epub 2013 Oct 16.

PMID:
24133142
[PubMed - indexed for MEDLINE]
3.

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's disease model.

Alters SE, McLaughlin B, Spink B, Lachinyan T, Wang CW, Podust V, Schellenberger V, Stemmer WP.

PLoS One. 2012;7(11):e50630. doi: 10.1371/journal.pone.0050630. Epub 2012 Nov 26. Corrected and republished in: PLoS One. 2013;8(6). doi: 10.1371/annotation/5c7138bd-5602-466d-8daf-e75e0b7d7fdb.

PMID:
23189208
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose.

Geething NC, To W, Spink BJ, Scholle MD, Wang CW, Yin Y, Yao Y, Schellenberger V, Cleland JL, Stemmer WP, Silverman J.

PLoS One. 2010 Apr 14;5(4):e10175. doi: 10.1371/journal.pone.0010175.

PMID:
20418955
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner.

Schellenberger V, Wang CW, Geething NC, Spink BJ, Campbell A, To W, Scholle MD, Yin Y, Yao Y, Bogin O, Cleland JL, Silverman J, Stemmer WP.

Nat Biotechnol. 2009 Dec;27(12):1186-90. doi: 10.1038/nbt.1588. Epub .

PMID:
19915550
[PubMed - indexed for MEDLINE]
6.

Peptide ligands specific to the oxidized form of Escherichia coli thioredoxin.

Scholle MD, Banach BS, Hamdan SM, Richardson CC, Kay BK.

Biochim Biophys Acta. 2008 Nov;1784(11):1735-41. doi: 10.1016/j.bbapap.2008.06.022. Epub 2008 Jul 11.

PMID:
18672101
[PubMed - indexed for MEDLINE]
Free Article
7.

Whole-genome detection of conditionally essential and dispensable genes in Escherichia coli via genetic footprinting.

Scholle MD, Gerdes SY.

Methods Mol Biol. 2008;416:83-102. doi: 10.1007/978-1-59745-321-9_6.

PMID:
18392962
[PubMed - indexed for MEDLINE]

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