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Results: 1 to 20 of 231

1.

Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells.

Castro R, Fernandes P, Laske T, Sousa MF, Genzel Y, Scharfenberg K, Alves PM, Coroadinha AS.

Appl Microbiol Biotechnol. 2015 May 21. [Epub ahead of print]

PMID:
25994255
2.

Robust Expansion of Human Pluripotent Stem Cells: Integration of Bioprocess Design With Transcriptomic and Metabolomic Characterization.

Silva MM, Rodrigues AF, Correia C, Sousa MF, Brito C, Coroadinha AS, Serra M, Alves PM.

Stem Cells Transl Med. 2015 May 15. pii: sctm.2014-0270. [Epub ahead of print]

PMID:
25979863
3.

Effect of degree of conversion on in vivo biocompatibility of flowable resin used for bioprotection of mini-implants.

Lacerda-Santos R, de Meneses IH, de Morais Sampaio GA, Pithon MM, Alves PM.

Angle Orthod. 2015 May 13. [Epub ahead of print]

PMID:
25970651
4.

Human amniocyte-derived cells are a promising cell host for adenoviral vector production under serum-free conditions.

Silva AC, Simão D, Küppers C, Lucas T, Sousa MF, Cruz P, Carrondo MJ, Kochanek S, Alves PM.

Biotechnol J. 2015 May;10(5):760-71. doi: 10.1002/biot.201400765.

PMID:
25943527
5.

Single step cloning-screening method:A new tool for developing and studying high-titer viral vector producer cells.

Rodrigues AF, Formas-Oliveira AS, Guerreiro MR, Tomás HA, Alves PM, Coroadinha AS.

Gene Ther. 2015 May 4. doi: 10.1038/gt.2015.44. [Epub ahead of print]

PMID:
25938191
6.

Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation.

Fernandes P, Almeida AI, Kremer EJ, Alves PM, Coroadinha AS.

Sci Rep. 2015 Mar 16;5:9135. doi: 10.1038/srep09135.

7.

Exploring continuous and integrated strategies for the up- and downstream processing of human mesenchymal stem cells.

Cunha B, Aguiar T, Silva MM, Silva RJ, Sousa MF, Pineda E, Peixoto C, Carrondo MJ, Serra M, Alves PM.

J Biotechnol. 2015 Mar 4. pii: S0168-1656(15)00078-4. doi: 10.1016/j.jbiotec.2015.02.023. [Epub ahead of print]

PMID:
25746903
8.

Robust design of adenovirus purification by two-column, simulated moving-bed, size-exclusion chromatography.

Nestola P, Silva RJ, Peixoto C, Alves PM, Carrondo MJ, Mota JP.

J Biotechnol. 2015 Mar 2. pii: S0168-1656(15)00076-0. doi: 10.1016/j.jbiotec.2015.01.030. [Epub ahead of print]

PMID:
25744665
9.

A multi-organ chip co-culture of neurospheres and liver equivalents for long-term substance testing.

Materne EM, Ramme AP, Terrasso AP, Serra M, Alves PM, Brito C, Sakharov DA, Tonevitsky AG, Lauster R, Marx U.

J Biotechnol. 2015 Jul 10;205:36-46. doi: 10.1016/j.jbiotec.2015.02.002. Epub 2015 Feb 9.

PMID:
25678136
10.

Improved virus purification processes for vaccines and gene therapy.

Nestola P, Peixoto C, Silva RR, Alves PM, Mota JP, Carrondo MJ.

Biotechnol Bioeng. 2015 May;112(5):843-57. doi: 10.1002/bit.25545. Epub 2015 Mar 10.

PMID:
25677990
11.

Stem cell-derived systems in toxicology assessment.

Suter-Dick L, Alves PM, Blaauboer BJ, Bremm KD, Brito C, Coecke S, Flick B, Fowler P, Hescheler J, Ingelman-Sundberg M, Jennings P, Kelm JM, Manou I, Mistry P, Moretto A, Roth A, Stedman D, van de Water B, Beilmann M.

Stem Cells Dev. 2015 Jun 1;24(11):1284-96. doi: 10.1089/scd.2014.0540. Epub 2015 Mar 31.

PMID:
25675366
12.

Association of immunoexpression of the galectins-3 and -7 with histopathological and clinical parameters in oral squamous cell carcinoma in young patients.

Mesquita JA, Queiroz LM, Silveira ÉJ, Gordon-Nunez MA, Godoy GP, Nonaka CF, Alves PM.

Eur Arch Otorhinolaryngol. 2015 Jan 14. [Epub ahead of print]

PMID:
25586662
13.

Novel scalable 3D cell based model for in vitro neurotoxicity testing: Combining human differentiated neurospheres with gene expression and functional endpoints.

Terrasso AP, Pinto C, Serra M, Filipe A, Almeida S, Ferreira AL, Pedroso P, Brito C, Alves PM.

J Biotechnol. 2015 Jul 10;205:82-92. doi: 10.1016/j.jbiotec.2014.12.011. Epub 2015 Jan 5.

PMID:
25573798
14.

Evaluation of novel large cut-off ultrafiltration membranes for adenovirus serotype 5 (Ad5) concentration.

Nestola P, Martins DL, Peixoto C, Roederstein S, Schleuss T, Alves PM, Mota JP, Carrondo MJ.

PLoS One. 2014 Dec 29;9(12):e115802. doi: 10.1371/journal.pone.0115802. eCollection 2014.

15.

Exploring analytical proteomics platforms toward the definition of human cardiac stem cells receptome.

Gomes-Alves P, Serra M, Brito C, R-Borlado L, López JA, Vázquez J, Carrondo MJ, Bernad A, Alves PM.

Proteomics. 2015 Apr;15(7):1332-7. doi: 10.1002/pmic.201400318. Epub 2015 Feb 5.

PMID:
25504917
16.

Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells.

Rodrigues AF, Carrondo MJ, Alves PM, Coroadinha AS.

Trends Biotechnol. 2014 Dec;32(12):602-7. doi: 10.1016/j.tibtech.2014.09.010. Epub 2014 Oct 28.

PMID:
25450042
17.

Impact of adenovirus life cycle progression on the generation of canine helper-dependent vectors.

Fernandes P, Simão D, Guerreiro MR, Kremer EJ, Coroadinha AS, Alves PM.

Gene Ther. 2015 Jan;22(1):40-9. doi: 10.1038/gt.2014.92. Epub 2014 Oct 23.

PMID:
25338917
18.

[Clinical, tomographic and histopathological aspects of the nasopalatine duct cyst].

Mesquita JA, Luna AH, Nonaka CF, Godoy GP, Alves PM.

Braz J Otorhinolaryngol. 2014 Sep-Oct;80(5):448-50. doi: 10.1016/j.bjorl.2014.05.020. Epub 2014 Jul 4. Portuguese. No abstract available.

19.

Modeling human neural functionality in vitro: three-dimensional culture for dopaminergic differentiation.

Simão D, Pinto C, Piersanti S, Weston A, Peddie CJ, Bastos AE, Licursi V, Schwarz SC, Collinson LM, Salinas S, Serra M, Teixeira AP, Saggio I, Lima PA, Kremer EJ, Schiavo G, Brito C, Alves PM.

Tissue Eng Part A. 2015 Feb;21(3-4):654-68. doi: 10.1089/ten.TEA.2014.0079. Epub 2014 Nov 11.

PMID:
25257211
20.

Evaluation of in situ expression of effector and regulatory cytokines, TLR, galectins and matrix metalloproteinases in oral manifestations of paracoccidioidomycosis.

de Araújo MS, Alves PM, de Lima LM, da Silva MF, de Lima Pereira SA, Rodrigues V Jr, Rodrigues DB.

Immunobiology. 2015 Jan;220(1):154-63. doi: 10.1016/j.imbio.2014.08.006. Epub 2014 Aug 14.

PMID:
25204704
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