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Results: 1 to 20 of 223

1.

Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation.

Fernandes P, Almeida AI, Kremer EJ, Alves PM, Coroadinha AS.

Sci Rep. 2015 Mar 16;5:9135. doi: 10.1038/srep09135.

2.

Exploring continuous and integrated strategies for the up- and downstream processing of human mesenchymal stem cells.

Cunha B, Aguiar T, Silva MM, Silva RJ, Sousa MF, Pineda E, Peixoto C, Carrondo MJ, Serra M, Alves PM.

J Biotechnol. 2015 Mar 4. pii: S0168-1656(15)00078-4. doi: 10.1016/j.jbiotec.2015.02.023. [Epub ahead of print]

PMID:
25746903
3.

Robust design of adenovirus purification by two-column, simulated moving-bed, size-exclusion chromatography.

Nestola P, Silva RJ, Peixoto C, Alves PM, Carrondo MJ, Mota JP.

J Biotechnol. 2015 Mar 2. pii: S0168-1656(15)00076-0. doi: 10.1016/j.jbiotec.2015.01.030. [Epub ahead of print]

PMID:
25744665
4.

A multi-organ chip co-culture of neurospheres and liver equivalents for long-term substance testing.

Materne EM, Ramme AP, Terrasso AP, Serra M, Alves PM, Brito C, Sakharov DA, Tonevitsky AG, Lauster R, Marx U.

J Biotechnol. 2015 Feb 9. pii: S0168-1656(15)00045-0. doi: 10.1016/j.jbiotec.2015.02.002. [Epub ahead of print]

PMID:
25678136
5.

Improved virus purification processes for vaccines and gene therapy.

Nestola P, Peixoto C, Silva RR, Alves PM, Mota JP, Carrondo MJ.

Biotechnol Bioeng. 2015 Feb 13. doi: 10.1002/bit.25545. [Epub ahead of print]

PMID:
25677990
6.

Stem cell derived (SCD) systems in toxicology assessment.

Suter-Dick L, Alves PM, Blaauboer BJ, Bremm KD, Brito C, Coecke S, Flick B, Fowler P, Hescheler J, Ingelman-Sundberg M, Jennings P, Kelm JM, Manou I, Mistry P, Moretto A, Roth A, Stedman D, van de Water B, Beilmann M.

Stem Cells Dev. 2015 Feb 12. [Epub ahead of print]

PMID:
25675366
7.

Association of immunoexpression of the galectins-3 and -7 with histopathological and clinical parameters in oral squamous cell carcinoma in young patients.

Mesquita JA, Queiroz LM, Silveira ÉJ, Gordon-Nunez MA, Godoy GP, Nonaka CF, Alves PM.

Eur Arch Otorhinolaryngol. 2015 Jan 14. [Epub ahead of print]

PMID:
25586662
8.

Novel scalable 3D cell based model for in vitro neurotoxicity testing: Combining human differentiated neurospheres with gene expression and functional endpoints.

Terrasso AP, Pinto C, Serra M, Filipe A, Almeida S, Ferreira AL, Pedroso P, Brito C, Alves PM.

J Biotechnol. 2015 Jan 5. pii: S0168-1656(14)01047-5. doi: 10.1016/j.jbiotec.2014.12.011. [Epub ahead of print]

PMID:
25573798
9.

Evaluation of novel large cut-off ultrafiltration membranes for adenovirus serotype 5 (Ad5) concentration.

Nestola P, Martins DL, Peixoto C, Roederstein S, Schleuss T, Alves PM, Mota JP, Carrondo MJ.

PLoS One. 2014 Dec 29;9(12):e115802. doi: 10.1371/journal.pone.0115802. eCollection 2014.

10.

Exploring analytical proteomics platforms toward the definition of human cardiac stem cells receptome.

Gomes-Alves P, Serra M, Brito C, R-Borlado L, López JA, Vázquez J, Carrondo MJ, Bernad A, Alves PM.

Proteomics. 2014 Dec 12. doi: 10.1002/pmic.201400318. [Epub ahead of print]

PMID:
25504917
11.

Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells.

Rodrigues AF, Carrondo MJ, Alves PM, Coroadinha AS.

Trends Biotechnol. 2014 Dec;32(12):602-7. doi: 10.1016/j.tibtech.2014.09.010. Epub 2014 Oct 28.

PMID:
25450042
12.

Impact of adenovirus life cycle progression on the generation of canine helper-dependent vectors.

Fernandes P, Simão D, Guerreiro MR, Kremer EJ, Coroadinha AS, Alves PM.

Gene Ther. 2015 Jan;22(1):40-9. doi: 10.1038/gt.2014.92. Epub 2014 Oct 23.

PMID:
25338917
13.

[Clinical, tomographic and histopathological aspects of the nasopalatine duct cyst].

Mesquita JA, Luna AH, Nonaka CF, Godoy GP, Alves PM.

Braz J Otorhinolaryngol. 2014 Sep-Oct;80(5):448-50. doi: 10.1016/j.bjorl.2014.05.020. Epub 2014 Jul 4. Portuguese. No abstract available.

14.

Modeling human neural functionality in vitro: three-dimensional culture for dopaminergic differentiation.

Simão D, Pinto C, Piersanti S, Weston A, Peddie CJ, Bastos AE, Licursi V, Schwarz SC, Collinson LM, Salinas S, Serra M, Teixeira AP, Saggio I, Lima PA, Kremer EJ, Schiavo G, Brito C, Alves PM.

Tissue Eng Part A. 2015 Feb;21(3-4):654-68. doi: 10.1089/ten.TEA.2014.0079. Epub 2014 Nov 11.

PMID:
25257211
15.

Evaluation of in situ expression of effector and regulatory cytokines, TLR, galectins and matrix metalloproteinases in oral manifestations of paracoccidioidomycosis.

de Araújo MS, Alves PM, de Lima LM, da Silva MF, de Lima Pereira SA, Rodrigues V Jr, Rodrigues DB.

Immunobiology. 2015 Jan;220(1):154-63. doi: 10.1016/j.imbio.2014.08.006. Epub 2014 Aug 14.

PMID:
25204704
16.

Imaging of human differentiated 3D neural aggregates using light sheet fluorescence microscopy.

Gualda EJ, Simão D, Pinto C, Alves PM, Brito C.

Front Cell Neurosci. 2014 Aug 6;8:221. doi: 10.3389/fncel.2014.00221. eCollection 2014.

17.

CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress.

Sarmento LM, Póvoa V, Nascimento R, Real G, Antunes I, Martins LR, Moita C, Alves PM, Abecasis M, Moita LF, Parkhouse RM, Meijerink JP, Barata JT.

Oncogene. 2014 Aug 18;0. doi: 10.1038/onc.2014.248. [Epub ahead of print]

PMID:
25132270
18.

HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism.

Rebelo SP, Costa R, Estrada M, Shevchenko V, Brito C, Alves PM.

Arch Toxicol. 2014 Aug 9. [Epub ahead of print]

PMID:
25107451
19.

Fatalities above 30,000 feet: characterizing pediatric deaths on commercial airline flights worldwide.

Rotta AT, Alves PM, Mason KE, Nerwich N, Speicher RH, Allareddy V, Allareddy V.

Pediatr Crit Care Med. 2014 Oct;15(8):e360-3. doi: 10.1097/PCC.0000000000000220.

PMID:
25072476
20.

Towards real-time monitoring of therapeutic protein quality in mammalian cell processes.

Pais DA, Carrondo MJ, Alves PM, Teixeira AP.

Curr Opin Biotechnol. 2014 Dec;30:161-7. doi: 10.1016/j.copbio.2014.06.019. Epub 2014 Jul 16. Review.

PMID:
25035940
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