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p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells.

Bailey JM, Hendley AM, Lafaro KJ, Pruski MA, Jones NC, Alsina J, Younes M, Maitra A, McAllister F, Iacobuzio-Donahue CA, Leach SD.

Oncogene. 2015 Nov 23. doi: 10.1038/onc.2015.441. [Epub ahead of print]


Continued smoking abstinence in diabetic patients in primary care: a cluster randomized controlled multicenter study.

Pérez-Tortosa S, Roig L, Manresa JM, Martin-Cantera C, Puigdomènech E, Roura P, Armengol A, Advani M; ITADI Study Group.

Diabetes Res Clin Pract. 2015 Jan;107(1):94-103. doi: 10.1016/j.diabres.2014.09.009. Epub 2014 Sep 30.


Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia.

McAllister F, Bailey JM, Alsina J, Nirschl CJ, Sharma R, Fan H, Rattigan Y, Roeser JC, Lankapalli RH, Zhang H, Jaffee EM, Drake CG, Housseau F, Maitra A, Kolls JK, Sears CL, Pardoll DM, Leach SD.

Cancer Cell. 2014 May 12;25(5):621-37. doi: 10.1016/j.ccr.2014.03.014.


Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.

Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators.

N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839.


DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer.

Bailey JM, Alsina J, Rasheed ZA, McAllister FM, Fu YY, Plentz R, Zhang H, Pasricha PJ, Bardeesy N, Matsui W, Maitra A, Leach SD.

Gastroenterology. 2014 Jan;146(1):245-56. doi: 10.1053/j.gastro.2013.09.050. Epub 2013 Oct 2.


Dissemination of a master surgeon: a study on the properties of an extraordinary individual.

Alsina J, LaFemina J.

Surgery. 2012 Sep;152(3 Suppl 1):S71-3. doi: 10.1016/j.surg.2012.05.023. No abstract available.


Sonic Hedgehog in pancreatic cancer: from bench to bedside, then back to the bench.

Rosow DE, Liss AS, Strobel O, Fritz S, Bausch D, Valsangkar NP, Alsina J, Kulemann B, Park JK, Yamaguchi J, LaFemina J, Thayer SP.

Surgery. 2012 Sep;152(3 Suppl 1):S19-32. doi: 10.1016/j.surg.2012.05.030. Epub 2012 Jul 6. Review. No abstract available.


Fifteen years of continuous improvement of quality care of type 2 diabetes mellitus in primary care in Catalonia, Spain.

Mata-Cases M, Roura-Olmeda P, Berengué-Iglesias M, Birulés-Pons M, Mundet-Tuduri X, Franch-Nadal J, Benito-Badorrey B, Cano-Pérez JF; Diabetes Study Group in Primary Health Care (GEDAPS: Grup d’Estudi de la Diabetis a l’Atenció Primària de Salut, Catalonian Society of Family and Community Medicine).

Int J Clin Pract. 2012 Mar;66(3):289-98. doi: 10.1111/j.1742-1241.2011.02872.x.


Liver-directed therapies in colorectal cancer.

Alsina J, Choti MA.

Semin Oncol. 2011 Aug;38(4):561-7. doi: 10.1053/j.seminoncol.2011.05.010. Review.


After 50 years of ethinylestradiol, another oestrogen in combined oral contraceptives.

Alsina JC.

Eur J Contracept Reprod Health Care. 2010 Feb;15(1):1-3. doi: 10.3109/13625180903585431. No abstract available.


Cluster randomized trial in smoking cessation with intensive advice in diabetic patients in primary care. ITADI Study.

Roig L, Perez S, Prieto G, Martin C, Advani M, Armengol A, Roura P, Manresa JM, Briones E; ITADI Study Group.

BMC Public Health. 2010 Feb 4;10:58. doi: 10.1186/1471-2458-10-58.


Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia.

Strobel O, Rosow DE, Rakhlin EY, Lauwers GY, Trainor AG, Alsina J, Fernández-Del Castillo C, Warshaw AL, Thayer SP.

Gastroenterology. 2010 Mar;138(3):1166-77. doi: 10.1053/j.gastro.2009.12.005. Epub 2009 Dec 21.


Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.

Scott WL, Alsina J, Audu CO, Babaev E, Cook L, Dage JL, Goodwin LA, Martynow JG, Matosiuk D, Royo M, Smith JG, Strong AT, Wickizer K, Woerly EM, Zhou Z, O'Donnell MJ.

J Comb Chem. 2009 Jan-Feb;11(1):14-33. doi: 10.1021/cc800184v.


Quality indicators and specifications for strategic and support processes in laboratory medicine.

Ricós C, Biosca C, Ibarz M, Minchinela J, Llopis M, Perich C, Alsina J, Alvarez V, Doménech V, Pastor RM, Sansalvador M, Isern GT, Navarro CV.

Clin Chem Lab Med. 2008;46(8):1189-94. doi: 10.1515/CCLM.2008.225.


In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia.

Strobel O, Dor Y, Alsina J, Stirman A, Lauwers G, Trainor A, Castillo CF, Warshaw AL, Thayer SP.

Gastroenterology. 2007 Dec;133(6):1999-2009. Epub 2007 Sep 14.


Backbone amide linker strategies for the solid-phase synthesis of C-terminal modified peptides.

Alsina J, Kates SA, Barany G, Albericio F.

Methods Mol Biol. 2005;298:195-208.


Detection of B-RAF and N-RAS mutations in human melanoma.

Goydos JS, Mann B, Kim HJ, Gabriel EM, Alsina J, Germino FJ, Shih W, Gorski DH.

J Am Coll Surg. 2005 Mar;200(3):362-70.


Solid-phase synthesis of constrained terminal and internal lactam peptidomimetics.

Scott WL, Alsina J, Kennedy JH, O'Donnell MJ.

Org Lett. 2004 May 13;6(10):1629-32.


Detection of mutations in the mitogen-activated protein kinase pathway in human melanoma.

Alsina J, Gorsk DH, Germino FJ, Shih W, Lu SE, Zhang ZG, Yang JM, Hait WN, Goydos JS.

Clin Cancer Res. 2003 Dec 15;9(17):6419-25.


Solid-phase synthesis of C-terminal modified peptides.

Alsina J, Albericio F.

Biopolymers. 2003;71(4):454-77. Review.

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