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Results: 1 to 20 of 116

1.

The role of hedgehog signalling in skeletal health and disease.

Alman BA.

Nat Rev Rheumatol. 2015 Jun 16. doi: 10.1038/nrrheum.2015.84. [Epub ahead of print] Review.

PMID:
26077918
2.

Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin.

Baht GS, Silkstone D, Vi L, Nadesan P, Amani Y, Whetstone H, Wei Q, Alman BA.

Nat Commun. 2015 May 19;6:7131. doi: 10.1038/ncomms8131.

3.

Generation of articular chondrocytes from human pluripotent stem cells.

Craft AM, Rockel JS, Nartiss Y, Kandel RA, Alman BA, Keller GM.

Nat Biotechnol. 2015 Jun;33(6):638-45. doi: 10.10.38/nbt.3210. Epub 2015 May 11.

PMID:
25961409
4.

Mutant IDH is sufficient to initiate enchondromatosis in mice.

Hirata M, Sasaki M, Cairns RA, Inoue S, Puviindran V, Li WY, Snow BE, Jones LD, Wei Q, Sato S, Tang YJ, Nadesan P, Rockel J, Whetstone H, Poon R, Weng A, Gross S, Straley K, Gliser C, Xu Y, Wunder J, Mak TW, Alman BA.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2829-34. doi: 10.1073/pnas.1424400112. Epub 2015 Feb 17.

5.

Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis.

Vi L, Baht GS, Whetstone H, Ng A, Wei Q, Poon R, Mylvaganam S, Grynpas M, Alman BA.

J Bone Miner Res. 2015 Jun;30(6):1090-102. doi: 10.1002/jbmr.2422.

PMID:
25487241
6.

Parameters for lithium treatment are critical in its enhancement of fracture-healing in rodents.

Bernick J, Wang Y, Sigal IA, Alman BA, Whyne CM, Nam D.

J Bone Joint Surg Am. 2014 Dec 3;96(23):1990-8. doi: 10.2106/JBJS.N.00057.

PMID:
25471914
7.

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.

Klingberg F, Chow ML, Koehler A, Boo S, Buscemi L, Quinn TM, Costell M, Alman BA, Genot E, Hinz B.

J Cell Biol. 2014 Oct 27;207(2):283-97. doi: 10.1083/jcb.201402006. Epub 2014 Oct 20.

8.

Development, validation and characterization of a novel mouse model of Adynamic Bone Disease (ABD).

Ng AH, Willett TL, Alman BA, Grynpas MD.

Bone. 2014 Nov;68:57-66. doi: 10.1016/j.bone.2014.07.037. Epub 2014 Aug 8.

PMID:
25111968
9.

Disruption of crosstalk between mesenchymal stromal and tumor cells in bone marrow as a therapeutic target to prevent metastatic bone disease.

Gordon JA, Lisle JW, Alman BA, Lian JB.

J Cell Physiol. 2014 Dec;229(12):1884-6. doi: 10.1002/jcp.24692.

PMID:
24905746
10.

β-Catenin-regulated myeloid cell adhesion and migration determine wound healing.

Amini-Nik S, Cambridge E, Yu W, Guo A, Whetstone H, Nadesan P, Poon R, Hinz B, Alman BA.

J Clin Invest. 2014 Jun;124(6):2599-610. doi: 10.1172/JCI62059. Epub 2014 May 16.

11.

Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth.

Campbell VT, Nadesan P, Ali SA, Wang CY, Whetstone H, Poon R, Wei Q, Keilty J, Proctor J, Wang LW, Apte SS, McGovern K, Alman BA, Wunder JS.

Mol Cancer Ther. 2014 May;13(5):1259-69. doi: 10.1158/1535-7163.MCT-13-0731. Epub 2014 Mar 14.

12.

Activation of hedgehog signaling during fracture repair enhances osteoblastic-dependent matrix formation.

Baht GS, Silkstone D, Nadesan P, Whetstone H, Alman BA.

J Orthop Res. 2014 Apr;32(4):581-6. doi: 10.1002/jor.22562. Epub 2013 Dec 17.

PMID:
24347536
13.

Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.

Lo WW, Wunder JS, Dickson BC, Campbell V, McGovern K, Alman BA, Andrulis IL.

Cancer. 2014 Feb 15;120(4):537-47. doi: 10.1002/cncr.28439. Epub 2013 Oct 21.

14.

Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis) by inhibiting hedgehog signaling.

Ghanbari-Azarnier R, Sato S, Wei Q, Al-Jazrawe M, Alman BA.

Neoplasia. 2013 Jul;15(7):712-9.

15.

Glucocorticoid treatment for the prevention of scoliosis in children with Duchenne muscular dystrophy: long-term follow-up.

Lebel DE, Corston JA, McAdam LC, Biggar WD, Alman BA.

J Bone Joint Surg Am. 2013 Jun 19;95(12):1057-61. doi: 10.2106/JBJS.L.01577.

PMID:
23783200
16.

Specification of chondrocytes and cartilage tissues from embryonic stem cells.

Craft AM, Ahmed N, Rockel JS, Baht GS, Alman BA, Kandel RA, Grigoriadis AE, Keller GM.

Development. 2013 Jun;140(12):2597-610. doi: 10.1242/dev.087890.

17.

Competency-based education: a new model for teaching orthopaedics.

Alman BA, Ferguson P, Kraemer W, Nousiainen MT, Reznick RK.

Instr Course Lect. 2013;62:565-9.

PMID:
23395058
18.

Patients' views on surgeons' financial conflicts of interest.

Camp MW, Mattingly DA, Gross AE, Nousiainen MT, Alman BA, McKneally MF.

J Bone Joint Surg Am. 2013 Jan 16;95(2):e9 1-8. doi: 10.2106/JBJS.L.00270.

PMID:
23324970
19.

Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes.

Ho L, Ali SA, Al-Jazrawe M, Kandel R, Wunder JS, Alman BA.

Oncogene. 2013 Nov 21;32(47):5388-96. doi: 10.1038/onc.2012.588. Epub 2012 Dec 17.

20.

Cutaneous wound healing: recruiting developmental pathways for regeneration.

Bielefeld KA, Amini-Nik S, Alman BA.

Cell Mol Life Sci. 2013 Jun;70(12):2059-81. doi: 10.1007/s00018-012-1152-9. Epub 2012 Oct 4. Review.

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