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Items: 1 to 20 of 125

1.

β-Catenin modulation in neurofibromatosis type 1 bone repair: therapeutic implications.

Ghadakzadeh S, Kannu P, Whetstone H, Howard A, Alman BA.

FASEB J. 2016 Jun 15. pii: fj.201500190RR. [Epub ahead of print]

PMID:
27306335
2.

Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis.

Rockel JS, Yu C, Whetstone H, Craft AM, Reilly K, Ma H, Tsushima H, Puviindran V, Al-Jazrawe M, Keller GM, Alman BA.

J Clin Invest. 2016 May 2;126(5):1649-63. doi: 10.1172/JCI80205. Epub 2016 Mar 28.

PMID:
27018594
3.

Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia.

Gray MJ, Kannu P, Sharma S, Neyt C, Zhang D, Paria N, Daniel PB, Whetstone H, Sprenger HG, Hammerschmidt P, Weng A, Dupuis L, Jobling R, Mendoza-Londono R, Dray M, Su P, Wilson MJ, Kapur RP, McCarthy EF, Alman BA, Howard A, Somers GR, Marshall CR, Manners S, Flanagan AM, Rathjen KE, Karol LA, Crawford H, Markie DM, Rios JJ, Wise CA, Robertson SP.

Am J Hum Genet. 2015 Dec 3;97(6):837-47. doi: 10.1016/j.ajhg.2015.11.001.

4.

Construct validity and reliability of a real-time multidimensional smartphone app to assess pain in children and adolescents with cancer.

Stinson JN, Jibb LA, Nguyen C, Nathan PC, Maloney AM, Dupuis LL, Gerstle JT, Hopyan S, Alman BA, Strahlendorf C, Portwine C, Johnston DL.

Pain. 2015 Dec;156(12):2607-15. doi: 10.1097/j.pain.0000000000000385.

PMID:
26580680
5.

Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma.

Wei Q, Tang YJ, Voisin V, Sato S, Hirata M, Whetstone H, Han I, Ailles L, Bader GD, Wunder J, Alman BA.

Oncotarget. 2015 Nov 24;6(37):40283-94. doi: 10.18632/oncotarget.5375.

6.

Adynamic Bone Decreases Bone Toughness During Aging by Affecting Mineral and Matrix.

Ng AH, Omelon S, Variola F, Allo B, Willett TL, Alman BA, Grynpas MD.

J Bone Miner Res. 2016 Feb;31(2):369-79. doi: 10.1002/jbmr.2702. Epub 2015 Oct 6.

PMID:
26332924
7.

Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage.

Ali SA, Al-Jazrawe M, Ma H, Whetstone H, Poon R, Farr S, Naples M, Adeli K, Alman BA.

Arthritis Rheumatol. 2016 Jan;68(1):127-37. doi: 10.1002/art.39337.

PMID:
26315393
8.

Erratum: Exposure to a youthful circulation rejuvenates bone repair through modulation of β-catenin.

Baht GS, Silkstone D, Vi L, Nadesan P, Amani Y, Whetstone H, Wei Q, Alman BA.

Nat Commun. 2015 Aug 26;6:7761. doi: 10.1038/ncomms8761. No abstract available.

9.

Bone Marrow Stress Decreases Osteogenic Progenitors.

Ng AH, Baht GS, Alman BA, Grynpas MD.

Calcif Tissue Int. 2015 Nov;97(5):476-86. doi: 10.1007/s00223-015-0032-3. Epub 2015 Jul 29.

PMID:
26220824
10.

The role of hedgehog signalling in skeletal health and disease.

Alman BA.

Nat Rev Rheumatol. 2015 Sep;11(9):552-60. doi: 10.1038/nrrheum.2015.84. Epub 2015 Jun 16. Review.

PMID:
26077918
11.

Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin.

Baht GS, Silkstone D, Vi L, Nadesan P, Amani Y, Whetstone H, Wei Q, Alman BA.

Nat Commun. 2015 May 19;6:7131. doi: 10.1038/ncomms8131. Erratum in: Nat Commun. 2015;6:7761.

12.

Generation of articular chondrocytes from human pluripotent stem cells.

Craft AM, Rockel JS, Nartiss Y, Kandel RA, Alman BA, Keller GM.

Nat Biotechnol. 2015 Jun;33(6):638-45. doi: 10.10.38/nbt.3210. Epub 2015 May 11.

PMID:
25961409
13.

Mutant IDH is sufficient to initiate enchondromatosis in mice.

Hirata M, Sasaki M, Cairns RA, Inoue S, Puviindran V, Li WY, Snow BE, Jones LD, Wei Q, Sato S, Tang YJ, Nadesan P, Rockel J, Whetstone H, Poon R, Weng A, Gross S, Straley K, Gliser C, Xu Y, Wunder J, Mak TW, Alman BA.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2829-34. doi: 10.1073/pnas.1424400112. Epub 2015 Feb 17.

14.

Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis.

Vi L, Baht GS, Whetstone H, Ng A, Wei Q, Poon R, Mylvaganam S, Grynpas M, Alman BA.

J Bone Miner Res. 2015 Jun;30(6):1090-102. doi: 10.1002/jbmr.2422.

15.

Parameters for lithium treatment are critical in its enhancement of fracture-healing in rodents.

Bernick J, Wang Y, Sigal IA, Alman BA, Whyne CM, Nam D.

J Bone Joint Surg Am. 2014 Dec 3;96(23):1990-8. doi: 10.2106/JBJS.N.00057.

16.

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.

Klingberg F, Chow ML, Koehler A, Boo S, Buscemi L, Quinn TM, Costell M, Alman BA, Genot E, Hinz B.

J Cell Biol. 2014 Oct 27;207(2):283-97. doi: 10.1083/jcb.201402006. Epub 2014 Oct 20.

17.

Development, validation and characterization of a novel mouse model of Adynamic Bone Disease (ABD).

Ng AH, Willett TL, Alman BA, Grynpas MD.

Bone. 2014 Nov;68:57-66. doi: 10.1016/j.bone.2014.07.037. Epub 2014 Aug 8.

PMID:
25111968
18.

Disruption of crosstalk between mesenchymal stromal and tumor cells in bone marrow as a therapeutic target to prevent metastatic bone disease.

Gordon JA, Lisle JW, Alman BA, Lian JB.

J Cell Physiol. 2014 Dec;229(12):1884-6. doi: 10.1002/jcp.24692.

19.

β-Catenin-regulated myeloid cell adhesion and migration determine wound healing.

Amini-Nik S, Cambridge E, Yu W, Guo A, Whetstone H, Nadesan P, Poon R, Hinz B, Alman BA.

J Clin Invest. 2014 Jun;124(6):2599-610. doi: 10.1172/JCI62059. Epub 2014 May 16.

20.

Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth.

Campbell VT, Nadesan P, Ali SA, Wang CY, Whetstone H, Poon R, Wei Q, Keilty J, Proctor J, Wang LW, Apte SS, McGovern K, Alman BA, Wunder JS.

Mol Cancer Ther. 2014 May;13(5):1259-69. doi: 10.1158/1535-7163.MCT-13-0731. Epub 2014 Mar 14.

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