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Items: 1 to 20 of 121

1.

Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production.

Detremmerie CM, Chen Z, Li Z, Alkharfy KM, Leung SW, Xu A, Gao Y, Vanhoutte PM.

J Pharmacol Exp Ther. 2016 Sep;358(3):558-68. doi: 10.1124/jpet.116.234153. Epub 2016 Jun 22.

2.

Quantification of lipid modified estrogenic derivative (ESC8) in rat plasma by LC-MS: application to a pharmacokinetic study.

Ahmad A, Mondal SK, Jan BL, Mukhopadhyay D, Banerjee R, Alkharfy KM.

Biomed Chromatogr. 2016 Jun 16. doi: 10.1002/bmc.3780. [Epub ahead of print]

PMID:
27306429
3.

Momordica charantia polysaccharides mitigate the progression of STZ induced diabetic nephropathy in rats.

Raish M, Ahmad A, Jan BL, Alkharfy KM, Ansari MA, Mohsin K, Jenoobi FA, Al-Mohizea A.

Int J Biol Macromol. 2016 Oct;91:394-9. doi: 10.1016/j.ijbiomac.2016.05.090. Epub 2016 May 26.

PMID:
27238589
4.

Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.

Mondal SK, Jinka S, Pal K, Nelli S, Dutta SK, Wang E, Ahmad A, AlKharfy KM, Mukhopadhyay D, Banerjee R.

Mol Pharm. 2016 Jul 5;13(7):2507-23. doi: 10.1021/acs.molpharmaceut.6b00230. Epub 2016 Jun 1.

PMID:
27184196
5.

Development of Liposomal Formulation for Delivering Anticancer Drug to Breast Cancer Stem-Cell-Like Cells and its Pharmacokinetics in an Animal Model.

Ahmad A, Mondal SK, Mukhopadhyay D, Banerjee R, Alkharfy KM.

Mol Pharm. 2016 Mar 7;13(3):1081-8. doi: 10.1021/acs.molpharmaceut.5b00900. Epub 2016 Feb 10.

PMID:
26832839
6.

Antioxidant Potential and In Situ Analysis of Major and Trace Element Determination of Ood-saleeb, a Known Unani Herbal Medicine by ICP-MS.

Raish M, Ahmad A, Alkharfy KM, Al-Jenoobi FI, Al-Mohizea AM, Mohsin K, Ahamad SR, Ali N, Shakeel F.

Biol Trace Elem Res. 2016 Aug;172(2):521-7. doi: 10.1007/s12011-015-0607-x. Epub 2016 Jan 13.

PMID:
26758866
7.

Effects of calcitriol on structural changes of kidney in C57BL/6J mouse model.

Alkharfy KM, Ahmed M, Yakout SM, Al-Daghri NM.

Int J Clin Exp Med. 2015 Aug 15;8(8):12390-6. eCollection 2015.

8.

Effects of Thymoquinone on the Pharmacokinetics and Pharmacodynamics of Glibenclamide in a Rat Model.

Ahmad A, Khan RM, Alkharfy KM, Raish M, Al-Jenoobi FI, Al-Mohizea AM.

Nat Prod Commun. 2015 Aug;10(8):1395-8.

PMID:
26434126
9.

N-acetyltransferase 1 and 2 polymorphisms and risk of diabetes mellitus type 2 in a Saudi population.

Al-Shaqha WM, Alkharfy KM, Al-Daghri NM, Mohammed AK.

Ann Saudi Med. 2015 May-Jun;35(3):214-21. doi: 10.5144/0256-4947.2015.214.

10.

Effect of Trigonella foenum-graecum L. on Metabolic Activity of CYP2D6 and CYP3A4.

Al-Jenoobi FI, Al-Thukair AA, Alam MA, Abbas FA, Al-Mohizea AM, Alkharfy KM, Al-Suwayeh SA.

Forsch Komplementmed. 2015;22(3):180-4. doi: 10.1159/000432412. Epub 2015 Jun 22.

PMID:
26335391
11.

Thymoquinone modulates nitric oxide production and improves organ dysfunction of sepsis.

Alkharfy KM, Ahmad A, Raish M, Vanhoutte PM.

Life Sci. 2015 Dec 15;143:131-8. doi: 10.1016/j.lfs.2015.08.007. Epub 2015 Aug 15.

PMID:
26285172
12.

Studies on Bronchodilator Activity of Salvia officinalis (Sage): Possible Involvement of K+ Channel Activation and Phosphodiesterase Inhibition.

Gilani AH, Rehman NU, Khan A, Alkharfy KM.

Phytother Res. 2015 Jun 1. doi: 10.1002/ptr.5384. [Epub ahead of print]

PMID:
26032019
13.

Potential inhibitory effect of herbal medicines on rat hepatic cytochrome P450 2D gene expression and metabolic activity.

Al-Jenoobi FI, Korashy HM, Ahad A, Raish M, Al-Mohizea AM, Alam MA, Al-Suwayeh SA, Alkharfy KM.

Pharmazie. 2014 Nov;69(11):799-803.

PMID:
25985573
14.

Hepatoprotective effect of Commiphora myrrha against d-GalN/LPS-induced hepatic injury in a rat model through attenuation of pro inflammatory cytokines and related genes.

Ahmad A, Raish M, Ganaie MA, Ahmad SR, Mohsin K, Al-Jenoobi FI, Al-Mohizea AM, Alkharfy KM.

Pharm Biol. 2015;53(12):1759-67. doi: 10.3109/13880209.2015.1005754. Epub 2015 Apr 13.

PMID:
25864920
15.

Modulation of CYP2D6 and CYP3A4 metabolic activities by Ferula asafetida resin.

Al-Jenoobi FI, Al-Thukair AA, Alam MA, Abbas FA, Al-Mohizea AM, Alkharfy KM, Al-Suwayeh SA.

Saudi Pharm J. 2014 Dec;22(6):564-9. doi: 10.1016/j.jsps.2014.03.004. Epub 2014 Apr 3.

16.

GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways.

Bhattacharya S, Pal K, Sharma AK, Dutta SK, Lau JS, Yan IK, Wang E, Elkhanany A, Alkharfy KM, Sanyal A, Patel TC, Chari ST, Spaller MR, Mukhopadhyay D.

PLoS One. 2014 Dec 3;9(12):e114409. doi: 10.1371/journal.pone.0114409. eCollection 2014.

17.

Application of Box-Behnken design for ultrasonic-assisted extraction of polysaccharides from Paeonia emodi.

Ahmad A, Alkharfy KM, Wani TA, Raish M.

Int J Biol Macromol. 2015 Jan;72:990-7. doi: 10.1016/j.ijbiomac.2014.10.011. Epub 2014 Oct 18.

PMID:
25453279
18.

Effects of fenugreek, garden cress, and black seed on theophylline pharmacokinetics in beagle dogs.

Al-Jenoobi FI, Ahad A, Mahrous GM, Al-Mohizea AM, AlKharfy KM, Al-Suwayeh SA.

Pharm Biol. 2015 Feb;53(2):296-300. doi: 10.3109/13880209.2014.916312. Epub 2014 Sep 22.

PMID:
25243874
19.

Inhibition of endoglin-GIPC interaction inhibits pancreatic cancer cell growth.

Pal K, Pletnev AA, Dutta SK, Wang E, Zhao R, Baral A, Yadav VK, Aggarwal S, Krishnaswamy S, Alkharfy KM, Chowdhury S, Spaller MR, Mukhopadhyay D.

Mol Cancer Ther. 2014 Oct;13(10):2264-75. doi: 10.1158/1535-7163.MCT-14-0291. Epub 2014 Aug 14.

20.

Impact of Herbal Medicines like Nigella sativa, Trigonella foenum-graecum, and Ferula asafoetida, on Cytochrome P450 2C11 Gene Expression in Rat Liver.

Korashy HM, Al-Jenoobi FI, Raish M, Ahad A, Al-Mohizea AM, Alam MA, Alkharfy KM, Al-Suwayeh SA.

Drug Res (Stuttg). 2015 Jul;65(7):366-72. doi: 10.1055/s-0034-1384604. Epub 2014 Aug 6.

PMID:
25099385
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