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Items: 17


Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress.

Li S, Papale LA, Zhang Q, Madrid A, Chen L, Chopra P, Keleş S, Jin P, Alisch RS.

Neurobiol Dis. 2016 Feb;86:99-108. doi: 10.1016/j.nbd.2015.11.010. Epub 2015 Nov 18.


Genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism.

Papale LA, Zhang Q, Li S, Chen K, Keleş S, Alisch RS.

Hum Mol Genet. 2015 Dec 15;24(24):7121-31. doi: 10.1093/hmg/ddv411. Epub 2015 Sep 30.


Hippocampal increase of 5-hmC in the glucocorticoid receptor gene following acute stress.

Li S, Papale LA, Kintner DB, Sabat G, Barrett-Wilt GA, Cengiz P, Alisch RS.

Behav Brain Res. 2015 Jun 1;286:236-40. doi: 10.1016/j.bbr.2015.03.002. Epub 2015 Mar 6.


Differentially methylated plasticity genes in the amygdala of young primates are linked to anxious temperament, an at risk phenotype for anxiety and depressive disorders.

Alisch RS, Chopra P, Fox AS, Chen K, White AT, Roseboom PH, Keles S, Kalin NH.

J Neurosci. 2014 Nov 19;34(47):15548-56. doi: 10.1523/JNEUROSCI.3338-14.2014.


Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice.

Chopra P, Papale LA, White AT, Hatch A, Brown RM, Garthwaite MA, Roseboom PH, Golos TG, Warren ST, Alisch RS.

BMC Genomics. 2014 Feb 13;15:131. doi: 10.1186/1471-2164-15-131.


Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1 locus.

Alisch RS, Wang T, Chopra P, Visootsak J, Conneely KN, Warren ST.

BMC Med Genet. 2013 Jan 29;14:18. doi: 10.1186/1471-2350-14-18.


Early-life disruption of epigenetic marks may contribute to the origins of mental illness.

Lee ER, Alisch RS.

Epigenomics. 2012 Aug;4(4):355-7. doi: 10.2217/epi.12.35. No abstract available.


Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence.

Gordon L, Joo JE, Powell JE, Ollikainen M, Novakovic B, Li X, Andronikos R, Cruickshank MN, Conneely KN, Smith AK, Alisch RS, Morley R, Visscher PM, Craig JM, Saffery R.

Genome Res. 2012 Aug;22(8):1395-406. doi: 10.1101/gr.136598.111. Epub 2012 Jul 16.


Influence of chronic administration of antidepressant drugs on mRNA for galanin, galanin receptors, and tyrosine hydroxylase in catecholaminergic and serotonergic cell-body regions in rat brain.

Rovin ML, Boss-Williams KA, Alisch RS, Ritchie JC, Weinshenker D, West CH, Weiss JM.

Neuropeptides. 2012 Apr;46(2):81-91. doi: 10.1016/j.npep.2012.01.001. Epub 2012 Feb 10.


Age-associated DNA methylation in pediatric populations.

Alisch RS, Barwick BG, Chopra P, Myrick LK, Satten GA, Conneely KN, Warren ST.

Genome Res. 2012 Apr;22(4):623-32. doi: 10.1101/gr.125187.111. Epub 2012 Feb 1.


Noncoding RNAs in mental retardation.

Szulwach KE, Jin P, Alisch RS.

Clin Genet. 2009 Mar;75(3):209-19. doi: 10.1111/j.1399-0004.2008.01134.x. Epub 2009 Jan 20. Review.


Argonaute2 is essential for mammalian gastrulation and proper mesoderm formation.

Alisch RS, Jin P, Epstein M, Caspary T, Warren ST.

PLoS Genet. 2007 Dec 28;3(12):e227. doi: 10.1371/journal.pgen.0030227.


Unconventional translation of mammalian LINE-1 retrotransposons.

Alisch RS, Garcia-Perez JL, Muotri AR, Gage FH, Moran JV.

Genes Dev. 2006 Jan 15;20(2):210-24.


RNA and microRNAs in fragile X mental retardation.

Jin P, Alisch RS, Warren ST.

Nat Cell Biol. 2004 Nov;6(11):1048-53. Review.


ATLAS: a system to selectively identify human-specific L1 insertions.

Badge RM, Alisch RS, Moran JV.

Am J Hum Genet. 2003 Apr;72(4):823-38. Epub 2003 Mar 11.


Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein.

Brunkow ME, Gardner JC, Van Ness J, Paeper BW, Kovacevich BR, Proll S, Skonier JE, Zhao L, Sabo PJ, Fu Y, Alisch RS, Gillett L, Colbert T, Tacconi P, Galas D, Hamersma H, Beighton P, Mulligan J.

Am J Hum Genet. 2001 Mar;68(3):577-89. Epub 2001 Feb 9.


A transient assay reveals that cultured human cells can accommodate multiple LINE-1 retrotransposition events.

Wei W, Morrish TA, Alisch RS, Moran JV.

Anal Biochem. 2000 Sep 10;284(2):435-8. No abstract available.

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