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Results: 1 to 20 of 97

1.

Cytotoxicity of surface-functionalized silicon and germanium nanoparticles: the dominant role of surface charges.

Bhattacharjee S, Rietjens IM, Singh MP, Atkins TM, Purkait TK, Xu Z, Regli S, Shukaliak A, Clark RJ, Mitchell BS, Alink GM, Marcelis AT, Fink MJ, Veinot JG, Kauzlarich SM, Zuilhof H.

Nanoscale. 2013 Jun 7;5(11):4870-83. doi: 10.1039/c3nr34266b. Epub 2013 Apr 25.

2.

In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.

Paini A, Punt A, Scholz G, Gremaud E, Spenkelink B, Alink G, Schilter B, van Bladeren PJ, Rietjens IM.

Mutagenesis. 2012 Nov;27(6):653-63. doi: 10.1093/mutage/ges031. Epub 2012 Jul 27.

3.

Cytotoxicity and cellular uptake of tri-block copolymer nanoparticles with different size and surface characteristics.

Bhattacharjee S, Ershov D, Fytianos K, van der Gucht J, Alink GM, Rietjens IM, Marcelis AT, Zuilhof H.

Part Fibre Toxicol. 2012 Apr 30;9:11. doi: 10.1186/1743-8977-9-11.

4.

Genotoxic effects in the Eastern mudminnow (Umbra pygmaea) after prolonged exposure to River Rhine water, as assessed by use of the in vivo SCE and Comet assays.

Penders EJ, Spenkelink A, Hoogenboezem W, Rotteveel SG, Maas JL, Alink GM.

Environ Mol Mutagen. 2012 May;53(4):304-10. doi: 10.1002/em.21687. Epub 2012 Mar 19.

PMID:
22430935
5.

Comparison of micro- and nanoscale Fe⁺³-containing (Hematite) particles for their toxicological properties in human lung cells in vitro.

Bhattacharya K, Hoffmann E, Schins RF, Boertz J, Prantl EM, Alink GM, Byrne HJ, Kuhlbusch TA, Rahman Q, Wiggers H, Schulz C, Dopp E.

Toxicol Sci. 2012 Mar;126(1):173-82. doi: 10.1093/toxsci/kfs014. Epub 2012 Jan 18.

6.

Surface charge-specific cytotoxicity and cellular uptake of tri-block copolymer nanoparticles.

Bhattacharjee S, Ershov D, Gucht Jv, Alink GM, Rietjens IM, Zuilhof H, Marcelis AT.

Nanotoxicology. 2013 Feb;7(1):71-84. doi: 10.3109/17435390.2011.633714. Epub 2011 Nov 17.

PMID:
22087472
7.

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells.

Bhattacharjee S, de Haan LH, Evers NM, Jiang X, Marcelis AT, Zuilhof H, Rietjens IM, Alink GM.

Part Fibre Toxicol. 2010 Sep 11;7:25. doi: 10.1186/1743-8977-7-25.

8.

An n-3 PUFA-rich microalgal oil diet protects to a similar extent as a fish oil-rich diet against AOM-induced colonic aberrant crypt foci in F344 rats.

van Beelen VA, Spenkelink B, Mooibroek H, Sijtsma L, Bosch D, Rietjens IM, Alink GM.

Food Chem Toxicol. 2009 Feb;47(2):316-20. doi: 10.1016/j.fct.2008.11.014. Epub 2008 Nov 18.

PMID:
19049816
9.

Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rats.

Schutte ME, Alink GM, Freidig AP, Spenkelink B, Vaessen JC, van de Sandt JJ, Groten JP, Rietjens IM.

Food Chem Toxicol. 2008 Nov;46(11):3422-8. doi: 10.1016/j.fct.2008.08.015. Epub 2008 Aug 22.

PMID:
18783729
10.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
11.

Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis.

Dihal AA, van der Woude H, Hendriksen PJ, Charif H, Dekker LJ, Ijsselstijn L, de Boer VC, Alink GM, Burgers PC, Rietjens IM, Woutersen RA, Stierum RH.

Proteomics. 2008 Jan;8(1):45-61.

PMID:
18095365
12.

Genotoxic effects in the Eastern mudminnow (Umbra pygmaea L.) after exposure to Rhine water, as assessed by use of the SCE and Comet assays: a comparison between 1978 and 2005.

Alink GM, Quik JT, Penders EJ, Spenkelink A, Rotteveel SG, Maas JL, Hoogenboezem W.

Mutat Res. 2007 Jul 28;631(2):93-100. Epub 2007 Apr 29.

PMID:
17561437
13.

A comparative study on the effect of algal and fish oil on viability and cell proliferation of Caco-2 cells.

van Beelen VA, Roeleveld J, Mooibroek H, Sijtsma L, Bino RJ, Bosch D, Rietjens IM, Alink GM.

Food Chem Toxicol. 2007 May;45(5):716-24. Epub 2006 Oct 28.

PMID:
17141934
14.

Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats.

Dihal AA, de Boer VC, van der Woude H, Tilburgs C, Bruijntjes JP, Alink GM, Rietjens IM, Woutersen RA, Stierum RH.

J Nutr. 2006 Nov;136(11):2862-7.

15.

An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers.

Schutte ME, Freidig AP, van de Sandt JJ, Alink GM, Rietjens IM, Groten JP.

Toxicol Appl Pharmacol. 2006 Dec 1;217(2):204-15. Epub 2006 Aug 10.

PMID:
16997339
16.

Future of toxicology--low-dose toxicology and risk--benefit analysis.

Rietjens IM, Alink GM.

Chem Res Toxicol. 2006 Aug;19(8):977-81.

PMID:
16918235
17.

Application of a continuous bioreactor cascade to study the effect of linoleic acid on hybridoma cell physiology.

Kisztelinski D, Alink GM, Rietjens IM, Bielecki S, Tramper J, Martens DE.

Biotechnol Bioeng. 2006 Oct 20;95(3):370-83.

PMID:
16894630
18.

Differential induction of electrophile-responsive element-regulated genes by n-3 and n-6 polyunsaturated fatty acids.

van Beelen VA, Aarts JM, Reus A, Mooibroek H, Sijtsma L, Bosch D, Rietjens IM, Alink GM.

FEBS Lett. 2006 Aug 21;580(19):4587-90. Epub 2006 Jul 20.

19.

Consequences of quercetin methylation for its covalent glutathione and DNA adduct formation.

van der Woude H, Boersma MG, Alink GM, Vervoort J, Rietjens IM.

Chem Biol Interact. 2006 Apr 15;160(3):193-203. Epub 2006 Mar 3.

PMID:
16516181
20.

The definition of hormesis and its implications for in vitro to in vivo extrapolation and risk assessment.

van der Woude H, Alink GM, Rietjens IM.

Crit Rev Toxicol. 2005 Jul;35(6):603-7. Review.

PMID:
16422398
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