Alhusainy W[Author] - Search Results

Year	Number of Results
2010	1
2012	1
2013	4
2014	3
2015	2
2016	2
2024	0

1

Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.

Probert PM, Palmer JM, Alhusainy W, Amer AO, Rietjens IM, White SA, Jones DE, Wright MC. Probert PM, et al. Among authors: alhusainy w. Toxicol Lett. 2016 Jan 22;243:98-110. doi: 10.1016/j.toxlet.2015.12.010. Epub 2015 Dec 29. Toxicol Lett. 2016. PMID: 26739637 Free PMC article.

2

The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.

Alhusainy W, Williams GM, Jeffrey AM, Iatropoulos MJ, Taylor S, Adams TB, Rietjens IM. Alhusainy W, et al. Food Chem Toxicol. 2014 Dec;74:28-34. doi: 10.1016/j.fct.2014.08.016. Epub 2014 Sep 10. Food Chem Toxicol. 2014. PMID: 25218219

3

Matrix-derived combination effect and risk assessment for estragole from basil-containing plant food supplements (PFS).

van den Berg SJ, Klaus V, Alhusainy W, Rietjens IM. van den Berg SJ, et al. Among authors: alhusainy w. Food Chem Toxicol. 2013 Dec;62:32-40. doi: 10.1016/j.fct.2013.08.019. Epub 2013 Aug 16. Food Chem Toxicol. 2013. PMID: 23959103 Free article.

4

Chemical analysis of estragole in fennel based teas and associated safety assessment using the Margin of Exposure (MOE) approach.

van den Berg SJ, Alhusainy W, Restani P, Rietjens IM. van den Berg SJ, et al. Among authors: alhusainy w. Food Chem Toxicol. 2014 Mar;65:147-54. doi: 10.1016/j.fct.2013.12.035. Epub 2013 Dec 30. Food Chem Toxicol. 2014. PMID: 24384409 Free article.

5

Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations.

Al-Subeihi AA, Alhusainy W, Kiwamoto R, Spenkelink B, van Bladeren PJ, Rietjens IM, Punt A. Al-Subeihi AA, et al. Among authors: alhusainy w. Toxicol Appl Pharmacol. 2015 Mar 1;283(2):117-26. doi: 10.1016/j.taap.2014.12.009. Epub 2014 Dec 27. Toxicol Appl Pharmacol. 2015. PMID: 25549870

6

Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I.

Abdullah R, Alhusainy W, Woutersen J, Rietjens IM, Punt A. Abdullah R, et al. Among authors: alhusainy w. Food Chem Toxicol. 2016 Jun;92:104-16. doi: 10.1016/j.fct.2016.03.017. Epub 2016 Mar 23. Food Chem Toxicol. 2016. PMID: 27016491

7

In vivo validation and physiologically based biokinetic modeling of the inhibition of SULT-mediated estragole DNA adduct formation in the liver of male Sprague-Dawley rats by the basil flavonoid nevadensin.

Alhusainy W, Paini A, van den Berg JH, Punt A, Scholz G, Schilter B, van Bladeren PJ, Taylor S, Adams TB, Rietjens IM. Alhusainy W, et al. Mol Nutr Food Res. 2013 Nov;57(11):1969-78. doi: 10.1002/mnfr.201300144. Epub 2013 Jul 26. Mol Nutr Food Res. 2013. PMID: 23894034

8

Inhibition of methyleugenol bioactivation by the herb-based constituent nevadensin and prediction of possible in vivo consequences using physiologically based kinetic modeling.

Al-Subeihi AA, Alhusainy W, Paini A, Punt A, Vervoort J, van Bladeren PJ, Rietjens IM. Al-Subeihi AA, et al. Among authors: alhusainy w. Food Chem Toxicol. 2013 Sep;59:564-71. doi: 10.1016/j.fct.2013.06.043. Epub 2013 Jul 4. Food Chem Toxicol. 2013. PMID: 23831728

9

Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect.

Alhusainy W, Paini A, Punt A, Louisse J, Spenkelink A, Vervoort J, Delatour T, Scholz G, Schilter B, Adams T, van Bladeren PJ, Rietjens IM. Alhusainy W, et al. Toxicol Appl Pharmacol. 2010 Jun 1;245(2):179-90. doi: 10.1016/j.taap.2010.02.017. Epub 2010 Mar 11. Toxicol Appl Pharmacol. 2010. PMID: 20226806

10

Matrix modulation of the bioactivation of estragole by constituents of different alkenylbenzene-containing herbs and spices and physiologically based biokinetic modeling of possible in vivo effects.

Alhusainy W, van den Berg SJ, Paini A, Campana A, Asselman M, Spenkelink A, Punt A, Scholz G, Schilter B, Adams TB, van Bladeren PJ, Rietjens IM. Alhusainy W, et al. Toxicol Sci. 2012 Sep;129(1):174-87. doi: 10.1093/toxsci/kfs196. Epub 2012 May 30. Toxicol Sci. 2012. PMID: 22649189

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