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Items: 16

1.

Inhaled loxapine and intramuscular lorazepam in healthy volunteers: a randomized placebo-controlled drug-drug interaction study.

Spyker DA, Cassella JV, Stoltz RR, Yeung PP.

Pharmacol Res Perspect. 2015 Dec 17;3(6):e00194. doi: 10.1002/prp2.194. eCollection 2015 Dec.

2.

A randomized, placebo-controlled repeat-dose thorough QT study of inhaled loxapine in healthy volunteers.

Cassella JV, Spyker DA, Yeung PP.

Int J Clin Pharmacol Ther. 2015 Nov;53(11):963-71.

3.

Multiple dose pharmacokinetics of inhaled loxapine in subjects on chronic, stable antipsychotic regimens.

Spyker DA, Riesenberg RA, Cassella JV.

J Clin Pharmacol. 2015 Sep;55(9):985-94. doi: 10.1002/jcph.502. Epub 2015 May 6.

PMID:
25808074
4.

Effect of smoking on the pharmacokinetics of inhaled loxapine.

Takahashi LH, Huie K, Spyker DA, Fishman RS, Cassella JV.

Ther Drug Monit. 2014 Oct;36(5):618-23. doi: 10.1097/FTD.0000000000000048.

5.

Loxapine delivered as a thermally generated aerosol does not prolong QTc in a thorough QT/QTc study in healthy subjects.

Spyker DA, Voloshko P, Heyman ER, Cassella JV.

J Clin Pharmacol. 2014 Jun;54(6):665-74. doi: 10.1002/jcph.257. Epub 2014 Jan 22.

PMID:
24375070
6.

Pulmonary delivery of therapeutic compounds for treating CNS disorders.

Noymer P, Biondi S, Myers D, Cassella J.

Ther Deliv. 2011 Sep;2(9):1125-40. Review.

PMID:
22833910
7.

Loxapine P-glycoprotein interactions in vitro.

Reed A, Huie K, Perloff ES, Cassella JV, Takahashi LH.

Drug Metab Lett. 2012 Mar;6(1):26-32.

PMID:
22300294
8.

Consistency of dosing with a thermal aerosol generation system: in vitro and in vivo correlation.

Myers DJ, Spyker DA, Dinh K, Quintana RJ, Biondi SA, Cassella JV.

Future Med Chem. 2011 Oct;3(13):1719-33. doi: 10.4155/fmc.11.122. Review. Erratum in: Future Med Chem. 2012 Jan;4(1):123.

PMID:
21942258
9.

In vitro aerosol characterization of Staccato(®) Loxapine.

Dinh K, Myers DJ, Glazer M, Shmidt T, Devereaux C, Simis K, Noymer PD, He M, Choosakul C, Chen Q, Cassella JV.

Int J Pharm. 2011 Jan 17;403(1-2):101-8. doi: 10.1016/j.ijpharm.2010.10.030. Epub 2010 Oct 31.

PMID:
20971174
10.

An investigation into the morphology of loxapine in a thermal aerosolization process from crystalline to amorphous.

Gao Q, Lew A, Takahashi LH, Cassella JV.

J Pharm Sci. 2011 Apr;100(4):1407-15. doi: 10.1002/jps.22364. Epub 2010 Oct 20.

PMID:
20963844
11.

Assessing the temperature of thermally generated inhalation aerosols.

Noymer PD, Myers DJ, Cassella JV, Timmons R.

J Aerosol Med Pulm Drug Deliv. 2011 Feb;24(1):11-5. doi: 10.1089/jamp.2010.0835. Epub 2010 Oct 20.

PMID:
20961165
12.

In vitro aerosol deposition in the oropharyngeal region for Staccato loxapine.

Dinh KV, Myers DJ, Noymer PD, Cassella JV.

J Aerosol Med Pulm Drug Deliv. 2010 Aug;23(4):253-60. doi: 10.1089/jamp.2009.0814.

PMID:
20528148
13.

Forced degradation of fentanyl: identification and analysis of impurities and degradants.

Garg A, Solas DW, Takahashi LH, Cassella JV.

J Pharm Biomed Anal. 2010 Nov 2;53(3):325-34. doi: 10.1016/j.jpba.2010.04.004. Epub 2010 Apr 13.

PMID:
20462721
14.

Pharmacokinetics of loxapine following inhalation of a thermally generated aerosol in healthy volunteers.

Spyker DA, Munzar P, Cassella JV.

J Clin Pharmacol. 2010 Feb;50(2):169-79. doi: 10.1177/0091270009347866. Epub 2009 Nov 13.

PMID:
19915181
15.

Nicotine aerosol generation from thermally reversible zinc halide complexes using the Staccato system.

Simis K, Lei M, Lu AT, Sharma KC, Hale RL, Timmons R, Cassella J.

Drug Dev Ind Pharm. 2008 Sep;34(9):936-42. doi: 10.1080/03639040802149061 .

PMID:
18800254
16.

The effect of film thickness on thermal aerosol generation.

Myers DJ, Timmons RD, Lu AT, Hale RL, Solas DW, Soni P, Rabinowitz JD.

Pharm Res. 2007 Feb;24(2):336-42. Epub 2006 Dec 19.

PMID:
17180726
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