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Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells.

Ali D, Hamam R, Alfayez M, Kassem M, Aldahmash A, Alajez NM.

Stem Cells Transl Med. 2016 May 18. pii: sctm.2015-0331. [Epub ahead of print]


microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection.

Hamam R, Ali AM, Alsaleh KA, Kassem M, Alfayez M, Aldahmash A, Alajez NM.

Sci Rep. 2016 May 16;6:25997. doi: 10.1038/srep25997.


Integrated Study of Globally Expressed microRNAs in IL-1β-stimulated Human Osteoarthritis Chondrocytes and Osteoarthritis Relevant Genes: A Microarray and Bioinformatics Analysis.

Rasheed Z, Al-Shobaili HA, Rasheed N, Al Salloom AA, Al-Shaya O, Mahmood A, Alajez NM, Alghamdi AS, Mehana el-SE.

Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):335-55. doi: 10.1080/15257770.2016.1163380. Epub 2016 May 6.


MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1.

Vishnubalaji R, Hamam R, Yue S, Al-Obeed O, Kassem M, Liu FF, Aldahmash A, Alajez NM.

Oncotarget. 2016 Apr 22. doi: 10.18632/oncotarget.8937. [Epub ahead of print]


Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model.

Vishnubalaji R, Atteya M, Al-Nbaheen M, Oreffo RO, Aldahmash A, Alajez NM.

Stem Cells Int. 2015;2015:257019. doi: 10.1155/2015/257019. Epub 2015 Jun 29.


CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells.

Al-toub M, Vishnubalaji R, Hamam R, Kassem M, Aldahmash A, Alajez NM.

Stem Cell Res Ther. 2015 Jul 24;6:135. doi: 10.1186/s13287-015-0123-0.


Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer.

Vishnubalaji R, Hamam R, Abdulla MH, Mohammed MA, Kassem M, Al-Obeed O, Aldahmash A, Alajez NM.

Cell Death Dis. 2015 Jan 22;6:e1614. doi: 10.1038/cddis.2014.556.


microRNAs as regulators of adipogenic differentiation of mesenchymal stem cells.

Hamam D, Ali D, Kassem M, Aldahmash A, Alajez NM.

Stem Cells Dev. 2015 Feb 15;24(4):417-25. doi: 10.1089/scd.2014.0331. Epub 2014 Dec 31. Review.


microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells.

Hamam D, Ali D, Vishnubalaji R, Hamam R, Al-Nbaheen M, Chen L, Kassem M, Aldahmash A, Alajez NM.

Cell Death Dis. 2014 Oct 30;5:e1499. doi: 10.1038/cddis.2014.462.


Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells.

Al-toub M, Almusa A, Almajed M, Al-Nbaheen M, Kassem M, Aldahmash A, Alajez NM.

Stem Cell Res Ther. 2013 Sep 17;4(5):114. doi: 10.1186/scrt325.


MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

How C, Hui AB, Alajez NM, Shi W, Boutros PC, Clarke BA, Yan R, Pintilie M, Fyles A, Hedley DW, Hill RP, Milosevic M, Liu FF.

PLoS One. 2013 Jul 4;8(7):e67846. doi: 10.1371/journal.pone.0067846. Print 2013.


Lin28b promotes head and neck cancer progression via modulation of the insulin-like growth factor survival pathway.

Alajez NM, Shi W, Wong D, Lenarduzzi M, Waldron J, Weinreb I, Liu FF.

Oncotarget. 2012 Dec;3(12):1641-52.


MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1.

Lenarduzzi M, Hui AB, Alajez NM, Shi W, Williams J, Yue S, O'Sullivan B, Liu FF.

PLoS One. 2013;8(1):e53765. doi: 10.1371/journal.pone.0053765. Epub 2013 Jan 15.


Enhanced vesicular stomatitis virus (VSVΔ51) targeting of head and neck cancer in combination with radiation therapy or ZD6126 vascular disrupting agent.

Alajez NM, Mocanu JD, Krushel T, Bell JC, Liu FF.

Cancer Cell Int. 2012 Jun 15;12(1):27. doi: 10.1186/1475-2867-12-27.


In vitro differentiation of human skin-derived multipotent stromal cells into putative endothelial-like cells.

Vishnubalaji R, Manikandan M, Al-Nbaheen M, Kadalmani B, Aldahmash A, Alajez NM.

BMC Dev Biol. 2012 Jan 27;12:7. doi: 10.1186/1471-213X-12-7.


Cancer stem cells. From characterization to therapeutic implications.

Alajez NM.

Saudi Med J. 2011 Dec;32(12):1229-34. Review.


Significance of dysregulated metadherin and microRNA-375 in head and neck cancer.

Hui AB, Bruce JP, Alajez NM, Shi W, Yue S, Perez-Ordonez B, Xu W, O'Sullivan B, Waldron J, Cummings B, Gullane P, Siu L, Liu FF.

Clin Cancer Res. 2011 Dec 15;17(24):7539-50. doi: 10.1158/1078-0432.CCR-11-2102. Epub 2011 Oct 26.


MicroRNA-301 mediates proliferation and invasion in human breast cancer.

Shi W, Gerster K, Alajez NM, Tsang J, Waldron L, Pintilie M, Hui AB, Sykes J, P'ng C, Miller N, McCready D, Fyles A, Liu FF.

Cancer Res. 2011 Apr 15;71(8):2926-37. doi: 10.1158/0008-5472.CAN-10-3369. Epub 2011 Mar 10.


MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway.

Alajez NM, Lenarduzzi M, Ito E, Hui AB, Shi W, Bruce J, Yue S, Huang SH, Xu W, Waldron J, O'Sullivan B, Liu FF.

Cancer Res. 2011 Mar 15;71(6):2381-91. doi: 10.1158/0008-5472.CAN-10-2754. Epub 2011 Mar 8.


Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98.

Alajez NM, Shi W, Hui AB, Bruce J, Lenarduzzi M, Ito E, Yue S, O'Sullivan B, Liu FF.

Cell Death Dis. 2010 Oct 21;1:e85. doi: 10.1038/cddis.2010.64.

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