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Results: 1 to 20 of 200

1.

Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ibα.

Gitz E, Koopman CD, Giannas A, Koekman CA, van den Heuvel DJ, Deckmyn H, Akkerman JW, Gerritsen HC, Urbanus RT.

Haematologica. 2013 Nov;98(11):1810-8. doi: 10.3324/haematol.2013.087221. Epub 2013 Jun 10.

PMID:
23753027
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ibα and Fc RIIa in immune thrombocytopenia.

Urbanus RT, van der Wal DE, Koekman CA, Huisman A, van den Heuvel DJ, Gerritsen HC, Deckmyn H, Akkerman JW, Schutgens RE, Gitz E.

Haematologica. 2013 Jul;98(7):e70-2. doi: 10.3324/haematol.2013.087874. Epub 2013 May 28. No abstract available.

PMID:
23716547
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci.

Paul DS, Albers CA, Rendon A, Voss K, Stephens J; HaemGen Consortium, van der Harst P, Chambers JC, Soranzo N, Ouwehand WH, Deloukas P.

Genome Res. 2013 Jul;23(7):1130-41. doi: 10.1101/gr.155127.113. Epub 2013 Apr 9.

PMID:
23570689
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Altered platelet contents in survivors of early ischemic ventricular fibrillation: preliminary findings.

De Jong JS, Nieuwland R, Meijers JC, Korporaal SJ, Akkerman JW, Wilde AA, Dekker LR.

Platelets. 2014;25(1):71-4. doi: 10.3109/09537104.2012.754418. Epub 2013 Jan 9.

PMID:
23301869
[PubMed - indexed for MEDLINE]
5.

Reactome - a curated knowledgebase of biological pathways: megakaryocytes and platelets.

Jupe S, Akkerman JW, Soranzo N, Ouwehand WH.

J Thromb Haemost. 2012 Nov;10(11):2399-402. doi: 10.1111/j.1538-7836.2012.04930.x. No abstract available.

PMID:
22985186
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.

Nürnberg ST, Rendon A, Smethurst PA, Paul DS, Voss K, Thon JN, Lloyd-Jones H, Sambrook JG, Tijssen MR; HaemGen Consortium, Italiano JE Jr, Deloukas P, Gottgens B, Soranzo N, Ouwehand WH.

Blood. 2012 Dec 6;120(24):4859-68. doi: 10.1182/blood-2012-01-401893. Epub 2012 Sep 12.

PMID:
22972982
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Improved platelet survival after cold storage by prevention of glycoprotein Ibα clustering in lipid rafts.

Gitz E, Koekman CA, van den Heuvel DJ, Deckmyn H, Akkerman JW, Gerritsen HC, Urbanus RT.

Haematologica. 2012 Dec;97(12):1873-81. doi: 10.3324/haematol.2012.066290. Epub 2012 Jun 24.

PMID:
22733027
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Induction of insulin resistance by the adipokines resistin, leptin, plasminogen activator inhibitor-1 and retinol binding protein 4 in human megakaryocytes.

Gerrits AJ, Gitz E, Koekman CA, Visseren FL, van Haeften TW, Akkerman JW.

Haematologica. 2012 Aug;97(8):1149-57. doi: 10.3324/haematol.2011.054916. Epub 2012 Apr 4.

PMID:
22491740
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Arachidonic acid depletion extends survival of cold-stored platelets by interfering with the [glycoprotein Ibα--14-3-3ζ] association.

van der Wal DE, Gitz E, Du VX, Lo KS, Koekman CA, Versteeg S, Akkerman JW.

Haematologica. 2012 Oct;97(10):1514-22. doi: 10.3324/haematol.2011.059956. Epub 2012 Feb 27.

PMID:
22371179
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The platelet P2Y12 receptor contributes to granule secretion through Ephrin A4 receptor.

Tournoij E, Koekman CA, Du VX, Roest M, Ruijtenbeek R, Moll FL, Akkerman JW.

Platelets. 2012;23(8):617-25. doi: 10.3109/09537104.2011.645924. Epub 2012 Jan 24.

PMID:
22273509
[PubMed - indexed for MEDLINE]
11.

New gene functions in megakaryopoiesis and platelet formation.

Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Mägi R, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, Ellinghaus D, Gögele M, Hottenga JJ, Langenberg C, Kovacs P, O'Reilly PF, Shin SY, Esko T, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, Ellen van der Schoot C, Allayee H, Attwood A, Balkau B, Bastardot F, Basu S, Baumeister SE, Biino G, Bomba L, Bonnefond A, Cambien F, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJ, Döring A, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen AL, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJ, Jolley J, Khaw KT, Kühnel B, Kyrtsonis MC, Lagou V, Lloyd-Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell BD, Montgomery GW, Nakamura Y, Nauck M, Navis G, Nöthlings U, Nolte IM, Porteous DJ, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WH, Taylor K, Tenesa A, Lay Thein S, Tönjes A, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, Völker U, Wichmann HE, Wiggins KL, Willemsen G, Yang TP, Hua Zhao J, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, Joost van Pelt L, Zwaginga JJ, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin MR, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman JW, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH, Soranzo N.

Nature. 2011 Nov 30;480(7376):201-8. doi: 10.1038/nature10659.

PMID:
22139419
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A novel small molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose mimics the antiplatelet actions of insulin.

Perveen R, Funk K, Thuma J, Wulf Ridge S, Cao Y, Akkerman JW, Chen X, Akbar H.

PLoS One. 2011;6(11):e26238. doi: 10.1371/journal.pone.0026238. Epub 2011 Nov 2.

PMID:
22073153
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Activated human platelet products induce proarrhythmic effects in ventricular myocytes.

de Jong JS, Verkerk AO, van Borren MM, Zakhrabova-Zwiauer OM, Nieuwland R, Meijers JC, Akkerman JW, Wilde AA, Tan HL, Dekker LR.

J Mol Cell Cardiol. 2011 Sep;51(3):347-56. doi: 10.1016/j.yjmcc.2011.05.016. Epub 2011 May 30.

PMID:
21651913
[PubMed - indexed for MEDLINE]
14.

Increased tissue factor expression in diabetes mellitus type 2 monocytes caused by insulin resistance.

Gerrits AJ, Koekman CA, van Haeften TW, Akkerman JW.

J Thromb Haemost. 2011 Apr;9(4):873-5. doi: 10.1111/j.1538-7836.2011.04201.x. No abstract available.

PMID:
21251203
[PubMed - indexed for MEDLINE]
15.

Deletion of the high-density lipoprotein receptor scavenger receptor BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol.

Korporaal SJ, Meurs I, Hauer AD, Hildebrand RB, Hoekstra M, Cate HT, Praticò D, Akkerman JW, Van Berkel TJ, Kuiper J, Van Eck M.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):34-42. doi: 10.1161/ATVBAHA.110.210252. Epub 2010 Nov 4.

PMID:
21051668
[PubMed - indexed for MEDLINE]
Free Article
16.

Platelet apoptosis by cold-induced glycoprotein Ibα clustering.

van der Wal DE, DU VX, Lo KS, Rasmussen JT, Verhoef S, Akkerman JW.

J Thromb Haemost. 2010 Nov;8(11):2554-62. doi: 10.1111/j.1538-7836.2010.04043.x.

PMID:
20735720
[PubMed - indexed for MEDLINE]
17.

Efficient inhibition of collagen-induced platelet activation and adhesion by LAIR-2, a soluble Ig-like receptor family member.

Lenting PJ, Westerlaken GH, Denis CV, Akkerman JW, Meyaard L.

PLoS One. 2010 Aug 13;5(8):e12174. doi: 10.1371/journal.pone.0012174.

PMID:
20730098
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Co-expression of the collagen receptors leukocyte-associated immunoglobulin-like receptor-1 and glycoprotein VI on a subset of megakaryoblasts.

Steevels TA, Westerlaken GH, Tijssen MR, Coffer PJ, Lenting PJ, Akkerman JW, Meyaard L.

Haematologica. 2010 Dec;95(12):2005-12. doi: 10.3324/haematol.2010.026120. Epub 2010 Aug 16.

PMID:
20713462
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Role of glycoprotein Ibalpha mobility in platelet function.

van der Wal DE, Verhoef S, Schutgens RE, Peters M, Wu Y, Akkerman JW.

Thromb Haemost. 2010 May;103(5):1033-43. doi: 10.1160/TH09-11-0751. Epub 2010 Mar 9.

PMID:
20216992
[PubMed - indexed for MEDLINE]
20.

Platelet tissue factor synthesis in type 2 diabetic patients is resistant to inhibition by insulin.

Gerrits AJ, Koekman CA, van Haeften TW, Akkerman JW.

Diabetes. 2010 Jun;59(6):1487-95. doi: 10.2337/db09-1008. Epub 2010 Mar 3.

PMID:
20200314
[PubMed - indexed for MEDLINE]
Free PMC Article

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