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Results: 1 to 20 of 1129

1.

Microbial Sensing by Toll-Like Receptors and Intracellular Nucleic Acid Sensors.

Pandey S, Kawai T, Akira S.

Cold Spring Harb Perspect Biol. 2014 Oct 9. pii: a016246. doi: 10.1101/cshperspect.a016246. [Epub ahead of print]

PMID:
25301932
[PubMed - as supplied by publisher]
2.

B Cell-Intrinsic TLR7 Signaling Is Essential for the Development of Spontaneous Germinal Centers.

Soni C, Wong EB, Domeier PP, Khan TN, Satoh T, Akira S, Rahman ZS.

J Immunol. 2014 Nov 1;193(9):4400-14. doi: 10.4049/jimmunol.1401720. Epub 2014 Sep 24.

PMID:
25252960
[PubMed - in process]
3.

Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization and K+ Efflux.

Franchi L, Eigenbrod T, Muñoz-Planillo R, Ozkurede U, Kim YG, Chakrabarti A, Gale M Jr, Silverman RH, Colonna M, Akira S, Núñez G.

J Immunol. 2014 Oct 15;193(8):4214-22. doi: 10.4049/jimmunol.1400582. Epub 2014 Sep 15.

PMID:
25225670
[PubMed - in process]
4.

JAK2V617F-positive myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2.

Kagoya Y, Yoshimi A, Tsuruta-Kishino T, Arai S, Satoh T, Akira S, Kurokawa M.

Blood. 2014 Sep 12. pii: blood-2014-04-570572. [Epub ahead of print]

PMID:
25217696
[PubMed - as supplied by publisher]
5.

Innate lymphoid cells regulate intestinal epithelial cell glycosylation.

Goto Y, Obata T, Kunisawa J, Sato S, Ivanov II, Lamichhane A, Takeyama N, Kamioka M, Sakamoto M, Matsuki T, Setoyama H, Imaoka A, Uematsu S, Akira S, Domino SE, Kulig P, Becher B, Renauld JC, Sasakawa C, Umesaki Y, Benno Y, Kiyono H.

Science. 2014 Sep 12;345(6202):1254009. doi: 10.1126/science.1254009. Epub 2014 Aug 21.

PMID:
25214634
[PubMed - indexed for MEDLINE]
6.

TRIF Signaling Drives Homeostatic Intestinal Epithelial Antimicrobial Peptide Expression.

Stockinger S, Duerr CU, Fulde M, Dolowschiak T, Pott J, Yang I, Eibach D, Bäckhed F, Akira S, Suerbaum S, Brugman M, Hornef MW.

J Immunol. 2014 Oct 15;193(8):4223-34. doi: 10.4049/jimmunol.1302708. Epub 2014 Sep 10.

PMID:
25210121
[PubMed - in process]
7.

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.

Ntziachristos P, Tsirigos A, Welstead GG, Trimarchi T, Bakogianni S, Xu L, Loizou E, Holmfeldt L, Strikoudis A, King B, Mullanders J, Becksfort J, Nedjic J, Paietta E, Tallman MS, Rowe JM, Tonon G, Satoh T, Kruidenier L, Prinjha R, Akira S, Van Vlierberghe P, Ferrando AA, Jaenisch R, Mullighan CG, Aifantis I.

Nature. 2014 Aug 17. doi: 10.1038/nature13605. [Epub ahead of print]

PMID:
25132549
[PubMed - as supplied by publisher]
8.

MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus.

Reynolds LA, Harcus Y, Smith KA, Webb LM, Hewitson JP, Ross EA, Brown S, Uematsu S, Akira S, Gray D, Gray M, MacDonald AS, Cunningham AF, Maizels RM.

J Immunol. 2014 Sep 15;193(6):2984-93. doi: 10.4049/jimmunol.1401056. Epub 2014 Aug 11.

PMID:
25114104
[PubMed - in process]
Free PMC Article
9.

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex.

Tartey S, Matsushita K, Vandenbon A, Ori D, Imamura T, Mino T, Standley DM, Hoffmann JA, Reichhart JM, Akira S, Takeuchi O.

EMBO J. 2014 Oct 16;33(20):2332-48. doi: 10.15252/embj.201488447. Epub 2014 Aug 8.

PMID:
25107474
[PubMed - in process]
10.

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis.

Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E.

J Clin Invest. 2014 Aug 1;124(8):3566-78. doi: 10.1172/JCI74068. Epub 2014 Jul 1.

PMID:
24983318
[PubMed - in process]
Free PMC Article
11.

The early activation of CD8+ T cells is dependent on type I IFN signaling following intramuscular vaccination of adenovirus vector.

Hemmi M, Tachibana M, Tsuzuki S, Shoji M, Sakurai F, Kawabata K, Kobiyama K, Ishii KJ, Akira S, Mizuguchi H.

Biomed Res Int. 2014;2014:158128. doi: 10.1155/2014/158128. Epub 2014 May 27.

PMID:
24971314
[PubMed - in process]
Free PMC Article
12.

Advanced scheduling for zygote intrafallopian transfer is possible via the use of a hormone replacement cycle for patients who have experienced repeated implantation failures.

Nakagawa K, Juen H, Nishi Y, Sugiyama R, Motoyama H, Kuribayashi Y, Inoue M, Akira S, Sugiyama R.

Arch Gynecol Obstet. 2014 Nov;290(5):1031-5. doi: 10.1007/s00404-014-3324-3. Epub 2014 Jun 26.

PMID:
24966120
[PubMed - in process]
13.

The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.

Choi J, Park S, Biering SB, Selleck E, Liu CY, Zhang X, Fujita N, Saitoh T, Akira S, Yoshimori T, Sibley LD, Hwang S, Virgin HW.

Immunity. 2014 Jun 19;40(6):924-35. doi: 10.1016/j.immuni.2014.05.006. Epub 2014 Jun 12.

PMID:
24931121
[PubMed - indexed for MEDLINE]
14.

Prospective signs of cleidocranial dysplasia in Cebpb deficiency.

Huang B, Takahashi K, Jennings EA, Pumtang-On P, Kiso H, Togo Y, Saito K, Sugai M, Akira S, Shimizu A, Bessho K.

J Biomed Sci. 2014 May 13;21:44. doi: 10.1186/1423-0127-21-44.

PMID:
24885110
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like receptor 3 knockout mice.

Leung YH, Nicholls JM, Ho CK, Sia SF, Mok CK, Valkenburg SA, Cheung P, Hui KP, Chan RW, Guan Y, Akira S, Peiris JS.

J Gen Virol. 2014 Sep;95(Pt 9):1870-9. doi: 10.1099/vir.0.066258-0. Epub 2014 May 30.

PMID:
24878639
[PubMed - in process]
16.

Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-κB activation.

Shinohara H, Behar M, Inoue K, Hiroshima M, Yasuda T, Nagashima T, Kimura S, Sanjo H, Maeda S, Yumoto N, Ki S, Akira S, Sako Y, Hoffmann A, Kurosaki T, Okada-Hatakeyama M.

Science. 2014 May 16;344(6185):760-4. doi: 10.1126/science.1250020.

PMID:
24833394
[PubMed - indexed for MEDLINE]
17.

Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria.

Zhao H, Aoshi T, Kawai S, Mori Y, Konishi A, Ozkan M, Fujita Y, Haseda Y, Shimizu M, Kohyama M, Kobiyama K, Eto K, Nabekura J, Horii T, Ishino T, Yuda M, Hemmi H, Kaisho T, Akira S, Kinoshita M, Tohyama K, Yoshioka Y, Ishii KJ, Coban C.

Cell Host Microbe. 2014 May 14;15(5):551-63. doi: 10.1016/j.chom.2014.04.008.

PMID:
24832450
[PubMed - in process]
18.

Epicutaneously applied Der p 2 induces a strong TH 2-biased antibody response in C57BL/6 mice, independent of functional TLR4.

Stremnitzer C, Manzano-Szalai K, Starkl P, Willensdorfer A, Schrom S, Singer J, Reichart U, Akira S, Jensen-Jarolim E.

Allergy. 2014 Jun;69(6):741-51. doi: 10.1111/all.12399. Epub 2014 Apr 16.

PMID:
24735481
[PubMed - in process]
Free PMC Article
19.

The enzyme Cyp26b1 mediates inhibition of mast cell activation by fibroblasts to maintain skin-barrier homeostasis.

Kurashima Y, Amiya T, Fujisawa K, Shibata N, Suzuki Y, Kogure Y, Hashimoto E, Otsuka A, Kabashima K, Sato S, Sato T, Kubo M, Akira S, Miyake K, Kunisawa J, Kiyono H.

Immunity. 2014 Apr 17;40(4):530-41. doi: 10.1016/j.immuni.2014.01.014. Epub 2014 Apr 10.

PMID:
24726878
[PubMed - indexed for MEDLINE]
20.

Nucleic acid sensing by T cells initiates Th2 cell differentiation.

Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T.

Nat Commun. 2014 Apr 10;5:3566. doi: 10.1038/ncomms4566.

PMID:
24717539
[PubMed - in process]

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