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Results: 1 to 20 of 240

1.

MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer.

Taniguchi K, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Ito Y, Otsuki Y, Uno B, Uchiyama K, Akao Y.

Cancer Lett. 2015 Jul 10;363(1):17-27. doi: 10.1016/j.canlet.2015.03.026. Epub 2015 Mar 24.

PMID:
25818238
2.

Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.

Taniguchi K, Ito Y, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Sugiyama T, Futamura M, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.

Sci Rep. 2015 Feb 27;5:8647. doi: 10.1038/srep08647.

3.

Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia.

Shinohara H, Taniguchi K, Kumazaki M, Yamada N, Ito Y, Otsuki Y, Uno B, Hayakawa F, Minami Y, Naoe T, Akao Y.

Cancer Lett. 2015 Apr 28;360(1):28-38. doi: 10.1016/j.canlet.2015.01.039. Epub 2015 Jan 30.

PMID:
25644089
4.

Age-induced reduction of autophagy-related gene expression is associated with onset of Alzheimer's disease.

Omata Y, Lim YM, Akao Y, Tsuda L.

Am J Neurodegener Dis. 2014 Dec 5;3(3):134-42. eCollection 2014.

5.

Relationship between expression of onco-related miRNAs and the endoscopic appearance of colorectal tumors.

Nakagawa Y, Akao Y, Taniguchi K, Kamatani A, Tahara T, Kamano T, Nakano N, Komura N, Ikuno H, Ohmori T, Jodai Y, Miyata M, Nagasaka M, Shibata T, Ohmiya N, Hirata I.

Int J Mol Sci. 2015 Jan 9;16(1):1526-43. doi: 10.3390/ijms16011526.

6.

Analysis of microRNA-203 function in CREB/MITF/RAB27a pathway: comparison between canine and human melanoma cells.

Noguchi S, Kumazaki M, Mori T, Baba K, Okuda M, Mizuno T, Akao Y.

Vet Comp Oncol. 2014 Oct 3. doi: 10.1111/vco.12118. [Epub ahead of print]

PMID:
25280339
7.

Colorectal cancer cell-derived microvesicles containing microRNA-1246 promote angiogenesis by activating Smad 1/5/8 signaling elicited by PML down-regulation in endothelial cells.

Yamada N, Tsujimura N, Kumazaki M, Shinohara H, Taniguchi K, Nakagawa Y, Naoe T, Akao Y.

Biochim Biophys Acta. 2014 Nov;1839(11):1256-72. doi: 10.1016/j.bbagrm.2014.09.002. Epub 2014 Sep 10.

PMID:
25218966
8.

Propolis cinnamic acid derivatives induce apoptosis through both extrinsic and intrinsic apoptosis signaling pathways and modulate of miRNA expression.

Kumazaki M, Shinohara H, Taniguchi K, Yamada N, Ohta S, Ichihara K, Akao Y.

Phytomedicine. 2014 Jul-Aug;21(8-9):1070-7. doi: 10.1016/j.phymed.2014.04.006. Epub 2014 May 20.

PMID:
24854570
9.

Stereocontrolled total synthesis of hedyotol A.

Kawabe Y, Ishikawa R, Akao Y, Yoshida A, Inai M, Asakawa T, Hamashima Y, Kan T.

Org Lett. 2014 Apr 4;16(7):1976-9. doi: 10.1021/ol500524y. Epub 2014 Mar 24.

PMID:
24660822
10.

Enantioselective synthesis of SB-203207.

Hirooka Y, Ikeuchi K, Kawamoto Y, Akao Y, Furuta T, Asakawa T, Inai M, Wakimoto T, Fukuyama T, Kan T.

Org Lett. 2014 Mar 21;16(6):1646-9. doi: 10.1021/ol5002973. Epub 2014 Mar 6.

PMID:
24601822
11.

Extracellular disposal of tumor-suppressor miRs-145 and -34a via microvesicles and 5-FU resistance of human colon cancer cells.

Akao Y, Khoo F, Kumazaki M, Shinohara H, Miki K, Yamada N.

Int J Mol Sci. 2014 Jan 20;15(1):1392-401. doi: 10.3390/ijms15011392.

12.

γ-Mangostin from Garcinia mangostana pericarps as a dual agonist that activates Both PPARα and PPARδ.

Matsuura N, Gamo K, Miyachi H, Iinuma M, Kawada T, Takahashi N, Akao Y, Tosa H.

Biosci Biotechnol Biochem. 2013;77(12):2430-5. Epub 2013 Dec 7.

14.

Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesicles.

Tsugita M, Yamada N, Noguchi S, Yamada K, Moritake H, Shimizu K, Akao Y, Ohno T.

PLoS One. 2013 Oct 4;8(10):e77416. doi: 10.1371/journal.pone.0077416. eCollection 2013.

15.

Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells.

Kumazaki M, Noguchi S, Yasui Y, Iwasaki J, Shinohara H, Yamada N, Akao Y.

J Nutr Biochem. 2013 Nov;24(11):1849-58. doi: 10.1016/j.jnutbio.2013.04.006. Epub 2013 Aug 16.

PMID:
23954321
16.

DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells.

Iio A, Takagi T, Miki K, Naoe T, Nakayama A, Akao Y.

Biochim Biophys Acta. 2013 Oct;1829(10):1102-10. doi: 10.1016/j.bbagrm.2013.07.010. Epub 2013 Aug 9.

PMID:
23932921
17.

Role of Intracellular and Extracellular MicroRNA-92a in Colorectal Cancer.

Yamada N, Nakagawa Y, Tsujimura N, Kumazaki M, Noguchi S, Mori T, Hirata I, Maruo K, Akao Y.

Transl Oncol. 2013 Aug 1;6(4):482-92. Print 2013 Aug.

18.

MicroRNA-203 regulates melanosome transport and tyrosinase expression in melanoma cells by targeting kinesin superfamily protein 5b.

Noguchi S, Kumazaki M, Yasui Y, Mori T, Yamada N, Akao Y.

J Invest Dermatol. 2014 Feb;134(2):461-9. doi: 10.1038/jid.2013.310. Epub 2013 Jul 22.

19.

Chemically modified siRNAs and miRNAs bearing urea/thiourea-bridged aromatic compounds at their 3'-end for RNAi therapy.

Kitamura Y, Masegi Y, Ogawa S, Nakashima R, Akao Y, Ueno Y, Kitade Y.

Bioorg Med Chem. 2013 Aug 1;21(15):4494-501. doi: 10.1016/j.bmc.2013.05.046. Epub 2013 Jun 4.

20.

MicroRNAs as tumour suppressors in canine and human melanoma cells and as a prognostic factor in canine melanomas.

Noguchi S, Mori T, Hoshino Y, Yamada N, Maruo K, Akao Y.

Vet Comp Oncol. 2013 Jun;11(2):113-23. doi: 10.1002/vco.306.

PMID:
23638671
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