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Results: 1 to 20 of 234

1.

Colorectal cancer cell-derived microvesicles containing microRNA-1246 promote angiogenesis by activating Smad 1/5/8 signaling elicited by PML down-regulation in endothelial cells.

Yamada N, Tsujimura N, Kumazaki M, Shinohara H, Taniguchi K, Nakagawa Y, Naoe T, Akao Y.

Biochim Biophys Acta. 2014 Sep 10. pii: S1874-9399(14)00234-X. doi: 10.1016/j.bbagrm.2014.09.002. [Epub ahead of print]

PMID:
25218966
[PubMed - as supplied by publisher]
2.

Propolis cinnamic acid derivatives induce apoptosis through both extrinsic and intrinsic apoptosis signaling pathways and modulate of miRNA expression.

Kumazaki M, Shinohara H, Taniguchi K, Yamada N, Ohta S, Ichihara K, Akao Y.

Phytomedicine. 2014 Jul-Aug;21(8-9):1070-7. doi: 10.1016/j.phymed.2014.04.006. Epub 2014 May 20.

PMID:
24854570
[PubMed - in process]
3.

Stereocontrolled total synthesis of hedyotol A.

Kawabe Y, Ishikawa R, Akao Y, Yoshida A, Inai M, Asakawa T, Hamashima Y, Kan T.

Org Lett. 2014 Apr 4;16(7):1976-9. doi: 10.1021/ol500524y. Epub 2014 Mar 24.

PMID:
24660822
[PubMed - indexed for MEDLINE]
4.

Enantioselective synthesis of SB-203207.

Hirooka Y, Ikeuchi K, Kawamoto Y, Akao Y, Furuta T, Asakawa T, Inai M, Wakimoto T, Fukuyama T, Kan T.

Org Lett. 2014 Mar 21;16(6):1646-9. doi: 10.1021/ol5002973. Epub 2014 Mar 6.

PMID:
24601822
[PubMed - indexed for MEDLINE]
5.

Extracellular disposal of tumor-suppressor miRs-145 and -34a via microvesicles and 5-FU resistance of human colon cancer cells.

Akao Y, Khoo F, Kumazaki M, Shinohara H, Miki K, Yamada N.

Int J Mol Sci. 2014 Jan 20;15(1):1392-401. doi: 10.3390/ijms15011392.

PMID:
24447928
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

γ-Mangostin from Garcinia mangostana pericarps as a dual agonist that activates Both PPARα and PPARδ.

Matsuura N, Gamo K, Miyachi H, Iinuma M, Kawada T, Takahashi N, Akao Y, Tosa H.

Biosci Biotechnol Biochem. 2013;77(12):2430-5. Epub 2013 Dec 7.

PMID:
24317060
[PubMed - indexed for MEDLINE]
Free Article
7.

Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia jurkat cells by modulating expression of fas-associated protein with death domain (FADD).

Yamada N, Noguchi S, Kumazaki M, Shinohara H, Miki K, Naoe T, Akao Y.

Biochim Biophys Acta. 2014 Mar;1843(3):590-602.

PMID:
24316133
[PubMed - indexed for MEDLINE]
8.

Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesicles.

Tsugita M, Yamada N, Noguchi S, Yamada K, Moritake H, Shimizu K, Akao Y, Ohno T.

PLoS One. 2013 Oct 4;8(10):e77416. doi: 10.1371/journal.pone.0077416. eCollection 2013.

PMID:
24124617
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells.

Kumazaki M, Noguchi S, Yasui Y, Iwasaki J, Shinohara H, Yamada N, Akao Y.

J Nutr Biochem. 2013 Nov;24(11):1849-58. doi: 10.1016/j.jnutbio.2013.04.006. Epub 2013 Aug 16.

PMID:
23954321
[PubMed - indexed for MEDLINE]
10.

DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells.

Iio A, Takagi T, Miki K, Naoe T, Nakayama A, Akao Y.

Biochim Biophys Acta. 2013 Oct;1829(10):1102-10. doi: 10.1016/j.bbagrm.2013.07.010. Epub 2013 Aug 9.

PMID:
23932921
[PubMed - indexed for MEDLINE]
11.

Role of Intracellular and Extracellular MicroRNA-92a in Colorectal Cancer.

Yamada N, Nakagawa Y, Tsujimura N, Kumazaki M, Noguchi S, Mori T, Hirata I, Maruo K, Akao Y.

Transl Oncol. 2013 Aug 1;6(4):482-92. Print 2013 Aug.

PMID:
23908691
[PubMed]
Free PMC Article
12.

MicroRNA-203 regulates melanosome transport and tyrosinase expression in melanoma cells by targeting kinesin superfamily protein 5b.

Noguchi S, Kumazaki M, Yasui Y, Mori T, Yamada N, Akao Y.

J Invest Dermatol. 2014 Feb;134(2):461-9. doi: 10.1038/jid.2013.310. Epub 2013 Jul 22.

PMID:
23884313
[PubMed - indexed for MEDLINE]
13.

Chemically modified siRNAs and miRNAs bearing urea/thiourea-bridged aromatic compounds at their 3'-end for RNAi therapy.

Kitamura Y, Masegi Y, Ogawa S, Nakashima R, Akao Y, Ueno Y, Kitade Y.

Bioorg Med Chem. 2013 Aug 1;21(15):4494-501. doi: 10.1016/j.bmc.2013.05.046. Epub 2013 Jun 4.

PMID:
23791869
[PubMed - indexed for MEDLINE]
Free Article
14.

MicroRNAs as tumour suppressors in canine and human melanoma cells and as a prognostic factor in canine melanomas.

Noguchi S, Mori T, Hoshino Y, Yamada N, Maruo K, Akao Y.

Vet Comp Oncol. 2013 Jun;11(2):113-23. doi: 10.1002/vco.306.

PMID:
23638671
[PubMed - indexed for MEDLINE]
15.

Chemically modified synthetic microRNA-205 inhibits the growth of melanoma cells in vitro and in vivo.

Noguchi S, Iwasaki J, Kumazaki M, Mori T, Maruo K, Sakai H, Yamada N, Shimada K, Naoe T, Kitade Y, Akao Y.

Mol Ther. 2013 Jun;21(6):1204-11. doi: 10.1038/mt.2013.70. Epub 2013 Apr 30.

PMID:
23629002
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Tumor-suppressive microRNA-145 targets catenin δ-1 to regulate Wnt/β-catenin signaling in human colon cancer cells.

Yamada N, Noguchi S, Mori T, Naoe T, Maruo K, Akao Y.

Cancer Lett. 2013 Jul 28;335(2):332-42. doi: 10.1016/j.canlet.2013.02.060. Epub 2013 Mar 7.

PMID:
23499891
[PubMed - indexed for MEDLINE]
17.

Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors.

Kamatani A, Nakagawa Y, Akao Y, Maruyama N, Nagasaka M, Shibata T, Tahara T, Hirata I.

Med Mol Morphol. 2013 Sep;46(3):166-71. doi: 10.1007/s00795-013-0020-5. Epub 2013 Feb 9.

PMID:
23397547
[PubMed - indexed for MEDLINE]
18.

socs7, a target gene of microRNA-145, regulates interferon-β induction through STAT3 nuclear translocation in bladder cancer cells.

Noguchi S, Yamada N, Kumazaki M, Yasui Y, Iwasaki J, Naito S, Akao Y.

Cell Death Dis. 2013 Feb 7;4:e482. doi: 10.1038/cddis.2013.11.

PMID:
23392170
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Occurrence of stilbene oligomers in Cyperus rhizomes.

Ito T, Endo H, Shinohara H, Oyama M, Akao Y, Iinuma M.

Fitoterapia. 2012 Dec;83(8):1420-9.

PMID:
23339254
[PubMed - indexed for MEDLINE]
20.

Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B.

Tanaka YT, Tanaka K, Kojima H, Hamada T, Masutani T, Tsuboi M, Akao Y.

Bioorg Med Chem Lett. 2013 Jan 15;23(2):518-23. doi: 10.1016/j.bmcl.2012.11.034. Epub 2012 Nov 21.

PMID:
23232059
[PubMed - indexed for MEDLINE]

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