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Results: 10

1.

Acquired resistance to mutant-selective EGFR inhibitor AZD9291 is associated with increased dependence on RAS signaling in preclinical models.

Eberlein CA, Stetson D, Markovets AA, Al-Kadhimi KJ, Lai Z, Fisher PR, Meador CB, Spitzler P, Ichihara E, Ross SJ, Ahdesmaki MJ, Ahmed A, Ratcliffe LE, O'Brien EL, Barnes CH, Brown H, Smith PD, Dry JR, Beran G, Thress KS, Dougherty B, Pao W, Cross DA.

Cancer Res. 2015 Apr 13. pii: canres.3167.2014. [Epub ahead of print]

PMID:
25870145
2.

A reliable method for the detection of BRCA1 and BRCA2 mutations in fixed tumour tissue utilising multiplex PCR-based targeted next generation sequencing.

Ellison G, Huang S, Carr H, Wallace A, Ahdesmaki M, Bhaskar S, Mills J.

BMC Clin Pathol. 2015 Mar 24;15:5. doi: 10.1186/s12907-015-0004-6. eCollection 2015.

3.

PIM kinase inhibitor AZD1208 for treatment of MYC-driven prostate cancer.

Kirschner AN, Wang J, van der Meer R, Anderson PD, Franco-Coronel OE, Kushner MH, Everett JH, Hameed O, Keeton EK, Ahdesmaki M, Grosskurth SE, Huszar D, Abdulkadir SA.

J Natl Cancer Inst. 2014 Dec 13;107(2). pii: dju407. doi: 10.1093/jnci/dju407. Print 2015 Feb.

PMID:
25505253
4.

A Predictive Genetic Signature for Response to Fluoropyrimidine-Based Neoadjuvant Chemoradiation in Clinical Stage II and III Rectal Cancer.

Chan J, Kinsella MT, Willis JE, Hu H, Reynolds H Jr, Delaney C, McCulla A, Deharo S, Ahdesmäki M, Allen WL, Johnston PG, Kinsella TJ.

Front Oncol. 2013 Nov 25;3:288. doi: 10.3389/fonc.2013.00288. eCollection 2013.

5.

Model selection for prognostic time-to-event gene signature discovery with applications in early breast cancer data.

Ahdesmäki M, Lancashire L, Proutski V, Wilson C, Davison TS, Harkin DP, Kennedy RD.

Stat Appl Genet Mol Biol. 2013 Oct 1;12(5):619-35. doi: 10.1515/sagmb-2012-0047.

PMID:
24077567
6.

Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue.

Kennedy RD, Bylesjo M, Kerr P, Davison T, Black JM, Kay EW, Holt RJ, Proutski V, Ahdesmaki M, Farztdinov V, Goffard N, Hey P, McDyer F, Mulligan K, Mussen J, O'Brien E, Oliver G, Walker SM, Mulligan JM, Wilson C, Winter A, O'Donoghue D, Mulcahy H, O'Sullivan J, Sheahan K, Hyland J, Dhir R, Bathe OF, Winqvist O, Manne U, Shanmugam C, Ramaswamy S, Leon EJ, Smith WI Jr, McDermott U, Wilson RH, Longley D, Marshall J, Cummins R, Sargent DJ, Johnston PG, Harkin DP.

J Clin Oncol. 2011 Dec 10;29(35):4620-6. doi: 10.1200/JCO.2011.35.4498. Epub 2011 Nov 7.

7.

Computational methods for estimation of cell cycle phase distributions of yeast cells.

Niemistö A, Nykter M, Aho T, Jalovaara H, Marjanen K, Ahdesmäki M, Ruusuvuori P, Tiainen M, Linne ML, Yli-Harja O.

EURASIP J Bioinform Syst Biol. 2007:46150. doi: 10.1155/2007/46150.

8.

Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data.

Ahdesmäki M, Lähdesmäki H, Gracey A, Shmulevich L, Yli-Harja O.

BMC Bioinformatics. 2007 Jul 2;8:233.

9.

Simulation of microarray data with realistic characteristics.

Nykter M, Aho T, Ahdesmäki M, Ruusuvuori P, Lehmussola A, Yli-Harja O.

BMC Bioinformatics. 2006 Jul 18;7:349.

10.

Robust detection of periodic time series measured from biological systems.

Ahdesmäki M, Lähdesmäki H, Pearson R, Huttunen H, Yli-Harja O.

BMC Bioinformatics. 2005 May 13;6:117.

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