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The pig X and Y Chromosomes: structure, sequence and evolution.

Skinner BM, Sargent CA, Churcher C, Hunt T, Herrero J, Loveland JE, Dunn M, Louzada S, Fu B, Chow W, Gilbert J, Austin-Guest S, Beal K, Carvalho-Silva D, Cheng W, Gordon D, Grafham D, Hardy M, Harley J, Hauser H, Howden P, Howe K, Lachani K, Ellis PJ, Kelly D, Kerry G, Kerwin J, Ng BL, Threadgold G, Wileman T, Wood JM, Yang F, Harrow J, Affara NA, Tyler-Smith C.

Genome Res. 2015 Nov 11. pii: gr.188839.114. [Epub ahead of print]


Expansion of the HSFY gene family in pig lineages : HSFY expansion in suids.

Skinner BM, Lachani K, Sargent CA, Yang F, Ellis P, Hunt T, Fu B, Louzada S, Churcher C, Tyler-Smith C, Affara NA.

BMC Genomics. 2015 Jun 9;16:442. doi: 10.1186/s12864-015-1650-x.


Impact on offspring methylation patterns of maternal gestational diabetes mellitus and intrauterine growth restraint suggest common genes and pathways linked to subsequent type 2 diabetes risk.

Quilter CR, Cooper WN, Cliffe KM, Skinner BM, Prentice PM, Nelson L, Bauer J, Ong KK, Constância M, Lowe WL, Affara NA, Dunger DB.

FASEB J. 2014 Nov;28(11):4868-79. doi: 10.1096/fj.14-255240. Epub 2014 Aug 21.


Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming.

Ellis PJ, Morris TJ, Skinner BM, Sargent CA, Vickers MH, Gluckman PD, Gilmour S, Affara NA.

BMC Genomics. 2014 Jan 21;15:49. doi: 10.1186/1471-2164-15-49.


Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds.

Fowler KE, Pong-Wong R, Bauer J, Clemente EJ, Reitter CP, Affara NA, Waite S, Walling GA, Griffin DK.

BMC Genomics. 2013 Nov 13;14:784. doi: 10.1186/1471-2164-14-784.


Regions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region.

Skinner BM, Lachani K, Sargent CA, Affara NA.

BMC Genet. 2013 Jan 15;14:3. doi: 10.1186/1471-2156-14-3.


A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse.

Cocquet J, Ellis PJ, Mahadevaiah SK, Affara NA, Vaiman D, Burgoyne PS.

PLoS Genet. 2012 Sep;8(9):e1002900. doi: 10.1371/journal.pgen.1002900. Epub 2012 Sep 13.


An association and haplotype analysis of porcine maternal infanticide: a model for human puerperal psychosis?

Quilter CR, Sargent CA, Bauer J, Bagga MR, Reiter CP, Hutchinson EL, Southwood OI, Evans G, Mileham A, Griffin DK, Affara NA.

Am J Med Genet B Neuropsychiatr Genet. 2012 Dec;159B(8):908-27. doi: 10.1002/ajmg.b.32097. Epub 2012 Sep 13.


The polymorphism analysis of CD169 and CD163 related with the risk of porcine reproductive and respiratory syndrome virus (PRRSV) infection.

Ren YW, Zhang YY, Affara NA, Sargent CA, Yang LG, Zhao JL, Fang LR, Wu JJ, Fang R, Tong Q, Xiao J, Li JL, Jiang YB, Chen HC, Zhang SJ.

Mol Biol Rep. 2012 Nov;39(11):9903-9. Epub 2012 Jun 28.


Association of multi-pathogenic infections with BAT2, CXCL12, Mx1 and EHMT2 variations in pigs.

Wang SJ, Liu WJ, Yang LG, Liu HB, Sargent CA, Affara NA, Zhang SJ.

Mol Biol Rep. 2012 Aug;39(8):8169-76. doi: 10.1007/s11033-012-1664-2. Epub 2012 Apr 25.


Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: a study of a unique resource in the Gambia.

Khulan B, Cooper WN, Skinner BM, Bauer J, Owens S, Prentice AM, Belteki G, Constancia M, Dunger D, Affara NA.

Hum Mol Genet. 2012 May 1;21(9):2086-101. doi: 10.1093/hmg/dds026. Epub 2012 Feb 3.


DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial.

Cooper WN, Khulan B, Owens S, Elks CE, Seidel V, Prentice AM, Belteki G, Ong KK, Affara NA, Constância M, Dunger DB.

FASEB J. 2012 May;26(5):1782-90. doi: 10.1096/fj.11-192708. Epub 2012 Jan 20.


Effects of FUT1 gene mutation on resistance to infectious disease.

Wang SJ, Liu WJ, Yang LG, Sargent CA, Liu HB, Wang C, Liu XD, Zhao SH, Affara NA, Liang AX, Zhang SJ.

Mol Biol Rep. 2012 Mar;39(3):2805-10. doi: 10.1007/s11033-011-1039-0. Epub 2011 Jun 22.


Effects of the polymorphisms of Mx1, BAT2 and CXCL12 genes on immunological traits in pigs.

Wang SJ, Liu WJ, Sargent CA, Zhao SH, Liu HB, Liu XD, Wang C, Hua GH, Yang LG, Affara NA, Zhang SJ.

Mol Biol Rep. 2012 Mar;39(3):2417-27. doi: 10.1007/s11033-011-0992-y. Epub 2011 Jun 12.


Association of Sly with sex-linked gene amplification during mouse evolution: a side effect of genomic conflict in spermatids?

Ellis PJ, Bacon J, Affara NA.

Hum Mol Genet. 2011 Aug 1;20(15):3010-21. doi: 10.1093/hmg/ddr204. Epub 2011 May 6.


An algorithm for determining the origin of trisomy and the positions of chiasmata from SNP genotype data.

Gabriel AS, Hassold TJ, Thornhill AR, Affara NA, Handyside AH, Griffin DK.

Chromosome Res. 2011 Feb;19(2):155-63. doi: 10.1007/s10577-010-9181-4. Epub 2011 Jan 12.


Deficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation.

Cocquet J, Ellis PJ, Yamauchi Y, Riel JM, Karacs TP, Rattigan A, Ojarikre OA, Affara NA, Ward MA, Burgoyne PS.

Mol Biol Cell. 2010 Oct 15;21(20):3497-505. doi: 10.1091/mbc.E10-07-0601. Epub 2010 Aug 25.


Analysis of X chromosome genomic DNA sequence copy number variation associated with premature ovarian failure (POF).

Quilter CR, Karcanias AC, Bagga MR, Duncan S, Murray A, Conway GS, Sargent CA, Affara NA.

Hum Reprod. 2010 Aug;25(8):2139-50. doi: 10.1093/humrep/deq158. Epub 2010 Jun 22.


The human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis.

Lopes AM, Miguel RN, Sargent CA, Ellis PJ, Amorim A, Affara NA.

BMC Mol Biol. 2010 May 7;11:33. doi: 10.1186/1471-2199-11-33.

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