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Results: 1 to 20 of 551

1.

LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance.

Rothaug M, Zunke F, Mazzulli JR, Schweizer M, Altmeppen H, Lüllmann-Rauch R, Kallemeijn WW, Gaspar P, Aerts JM, Glatzel M, Saftig P, Krainc D, Schwake M, Blanz J.

Proc Natl Acad Sci U S A. 2014 Oct 14. pii: 201405700. [Epub ahead of print]

PMID:
25316793
[PubMed - as supplied by publisher]
2.

Label-Free LC-MSe in Tissue and Serum Reveals Protein Networks Underlying Differences between Benign and Malignant Serous Ovarian Tumors.

Wegdam W, Argmann CA, Kramer G, Vissers JP, Buist MR, Kenter GG, Aerts JM, Meijer D, Moerland PD.

PLoS One. 2014 Sep 29;9(9):e108046. doi: 10.1371/journal.pone.0108046. eCollection 2014.

PMID:
25265318
[PubMed - in process]
Free PMC Article
3.

Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B cell malignancy.

Pavlova EV, Archer J, Wang S, Dekker N, Aerts JM, Karlsson S, Cox TM.

J Pathol. 2014 Sep 25. doi: 10.1002/path.4452. [Epub ahead of print]

PMID:
25256118
[PubMed - as supplied by publisher]
4.

Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors.

Ghisaidoobe AT, van den Berg RJ, Butt SS, Strijland A, Donker-Koopman WE, Scheij S, van den Nieuwendijk AM, Koomen GJ, van Loevezijn A, Leemhuis M, Wennekes T, van der Stelt M, van der Marel GA, van Boeckel CA, Aerts JM, Overkleeft HS.

J Med Chem. 2014 Oct 17. [Epub ahead of print]

PMID:
25250725
[PubMed - as supplied by publisher]
5.

Sequence Diversity Diagram for comparative analysis of multiple sequence alignments.

Sakai R, Aerts J.

BMC Proc. 2014 Aug 28;8(Suppl 2 Proceedings of the 3rd Annual Symposium on Biologica):S9. doi: 10.1186/1753-6561-8-S2-S9. eCollection 2014.

PMID:
25237396
[PubMed]
Free PMC Article
6.

dendsort: modular leaf ordering methods for dendrogram representations in R.

Sakai R, Winand R, Verbeiren T, Moere AV, Aerts J.

F1000Res. 2014 Jul 30;3:177. doi: 10.12688/f1000research.4784.1. eCollection 2014.

PMID:
25232468
[PubMed]
Free PMC Article
7.

Improvement in population-based survival of stage IV NSCLC due to increased use of chemotherapy.

Aarts MJ, van den Borne BE, Biesma B, Kloover JS, Aerts JG, Lemmens VE.

Int J Cancer. 2014 Sep 15. doi: 10.1002/ijc.29216. [Epub ahead of print]

PMID:
25219898
[PubMed - as supplied by publisher]
8.

Analysis of endogenous nucleotides by single cell capillary electrophoresis-mass spectrometry.

Liu JX, Aerts JT, Rubakhin SS, Zhang XX, Sweedler JV.

Analyst. 2014 Oct 15;139(22):5835-42. doi: 10.1039/c4an01133c.

PMID:
25212237
[PubMed - in process]
9.

Duplication of a promiscuous transcription factor drives the emergence of a new regulatory network.

Pougach K, Voet A, Kondrashov FA, Voordeckers K, Christiaens JF, Baying B, Benes V, Sakai R, Aerts J, Zhu B, Van Dijck P, Verstrepen KJ.

Nat Commun. 2014 Sep 10;5:4868. doi: 10.1038/ncomms5868.

PMID:
25204769
[PubMed - in process]
Free PMC Article
10.

Guidance on current good radiopharmacy practice for the small-scale preparation of radiopharmaceuticals using automated modules: a European perspective.

Aerts J, Ballinger JR, Behe M, Decristoforo C, Elsinga PH, Faivre-Chauvet A, Mindt TL, Kolenc Peitl P, Todde SC, Koziorowski J.

J Labelled Comp Radiopharm. 2014 Aug;57(10):615-20. doi: 10.1002/jlcr.3227. Epub 2014 Sep 5.

PMID:
25196257
[PubMed - in process]
11.

Ratio of intratumoral macrophage phenotypes is a prognostic factor in epithelioid malignant pleural mesothelioma.

Cornelissen R, Lievense LA, Maat AP, Hendriks RW, Hoogsteden HC, Bogers AJ, Hegmans JP, Aerts JG.

PLoS One. 2014 Sep 5;9(9):e106742. doi: 10.1371/journal.pone.0106742. eCollection 2014.

PMID:
25192022
[PubMed - in process]
Free PMC Article
12.

Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors.

Li KY, Jiang J, Witte MD, Kallemeijn WW, Donker-Koopman WE, Boot RG, Aerts JM, Codée JD, van der Marel GA, Overkleeft HS.

Org Biomol Chem. 2014 Oct 21;12(39):7786-91. doi: 10.1039/c4ob01611d. Epub 2014 Aug 26.

PMID:
25156485
[PubMed - in process]
13.

AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells.

Maenhout SK, Du Four S, Corthals J, Neyns B, Thielemans K, Aerts JL.

Oncotarget. 2014 Aug 30;5(16):6801-15.

PMID:
25149535
[PubMed - in process]
Free PMC Article
14.

MALDI-guided SIMS: Multiscale Imaging of Metabolites in Bacterial Biofilms.

Lanni EJ, Masyuko RN, Driscoll CM, Aerts JT, Shrout JD, Bohn PW, Sweedler JV.

Anal Chem. 2014 Sep 16;86(18):9139-45. doi: 10.1021/ac5020222. Epub 2014 Aug 26.

PMID:
25133532
[PubMed - in process]
Free PMC Article
15.

ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.

Tan YL, Genereux JC, Pankow S, Aerts JM, Yates JR 3rd, Kelly JW.

Chem Biol. 2014 Aug 14;21(8):967-76. doi: 10.1016/j.chembiol.2014.06.008.

PMID:
25126989
[PubMed - in process]
16.

Potent and selective activity-based probes for GH27 human retaining α-galactosidases.

Willems LI, Beenakker TJ, Murray B, Scheij S, Kallemeijn WW, Boot RG, Verhoek M, Donker-Koopman WE, Ferraz MJ, van Rijssel ER, Florea BI, Codée JD, van der Marel GA, Aerts JM, Overkleeft HS.

J Am Chem Soc. 2014 Aug 20;136(33):11622-5. doi: 10.1021/ja507040n. Epub 2014 Aug 11.

PMID:
25105979
[PubMed - in process]
17.

Design and synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates.

Duivenvoorden BA, Ghauharali K, Scheij S, Boot RG, Aerts JM, van der Marel GA, Overkleeft HS, Codée JD.

Carbohydr Res. 2014 Jul 18. pii: S0008-6215(14)00284-5. doi: 10.1016/j.carres.2014.07.007. [Epub ahead of print]

PMID:
25104395
[PubMed - as supplied by publisher]
18.

From covalent glycosidase inhibitors to activity-based glycosidase probes.

Willems LI, Jiang J, Li KY, Witte MD, Kallemeijn WW, Beenakker TJ, Schröder SP, Aerts JM, van der Marel GA, Codée JD, Overkleeft HS.

Chemistry. 2014 Aug 25;20(35):10864-72. doi: 10.1002/chem.201404014. Epub 2014 Aug 5.

PMID:
25100671
[PubMed - in process]
19.

Selective chaperone effect of aminocyclitol derivatives on G202R and other mutant glucocerebrosidases causing Gaucher disease.

Serra-Vinardell J, Díaz L, Guitiérrez-de Terán H, Sánchez-Ollé G, Bujons J, Michelakakis H, Mavridou I, Aerts JM, Delgado A, Grinberg D, Vilageliu L, Casas J.

Int J Biochem Cell Biol. 2014 Sep;54:245-54. doi: 10.1016/j.biocel.2014.07.017. Epub 2014 Jul 30.

PMID:
25084554
[PubMed - in process]
20.

Immunomodulation in cancer.

Hegmans JP, Aerts JG.

Curr Opin Pharmacol. 2014 Aug;17C:17-21. doi: 10.1016/j.coph.2014.06.007. Epub 2014 Jul 8. Review.

PMID:
25011112
[PubMed - as supplied by publisher]

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