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Results: 10

1.

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.

Fu J, Kanne DB, Leong M, Glickman LH, McWhirter SM, Lemmens E, Mechette K, Leong JJ, Lauer P, Liu W, Sivick KE, Zeng Q, Soares KC, Zheng L, Portnoy DA, Woodward JJ, Pardoll DM, Dubensky TW Jr, Kim Y.

Sci Transl Med. 2015 Apr 15;7(283):283ra52. doi: 10.1126/scitranslmed.aaa4306.

PMID:
25877890
2.

Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes-Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer.

Le DT, Wang-Gillam A, Picozzi V, Greten TF, Crocenzi T, Springett G, Morse M, Zeh H, Cohen D, Fine RL, Onners B, Uram JN, Laheru DA, Lutz ER, Solt S, Murphy AL, Skoble J, Lemmens E, Grous J, Dubensky T Jr, Brockstedt DG, Jaffee EM.

J Clin Oncol. 2015 Apr 20;33(12):1325-33. doi: 10.1200/JCO.2014.57.4244. Epub 2015 Jan 12.

PMID:
25584002
3.

Glutathione activates virulence gene expression of an intracellular pathogen.

Reniere ML, Whiteley AT, Hamilton KL, John SM, Lauer P, Brennan RG, Portnoy DA.

Nature. 2015 Jan 8;517(7533):170-3. doi: 10.1038/nature14029.

PMID:
25567281
4.
5.

Attenuated Listeria monocytogenes reprograms M2-polarized tumor-associated macrophages in ovarian cancer leading to iNOS-mediated tumor cell lysis.

Lizotte PH, Baird JR, Stevens CA, Lauer P, Green WR, Brockstedt DG, Fiering SN.

Oncoimmunology. 2014 May 23;3:e28926. eCollection 2014.

6.

Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants.

Dubensky TW Jr, Kanne DB, Leong ML.

Ther Adv Vaccines. 2013 Nov;1(4):131-43. doi: 10.1177/2051013613501988. Review.

7.

A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.

Keenan BP, Saenger Y, Kafrouni MI, Leubner A, Lauer P, Maitra A, Rucki AA, Gunderson AJ, Coussens LM, Brockstedt DG, Dubensky TW Jr, Hassan R, Armstrong TD, Jaffee EM.

Gastroenterology. 2014 Jun;146(7):1784-94.e6. doi: 10.1053/j.gastro.2014.02.055. Epub 2014 Mar 6.

PMID:
24607504
8.

Enhanced virus-specific CD8+ T cell responses by Listeria monocytogenes-infected dendritic cells in the context of Tim-3 blockade.

Ma CJ, Ren JP, Li GY, Wu XY, Brockstedt DG, Lauer P, Moorman JP, Yao ZQ.

PLoS One. 2014 Jan 31;9(1):e87821. doi: 10.1371/journal.pone.0087821. eCollection 2014.

9.

Killed but metabolically active vaccines.

Dubensky TW Jr, Skoble J, Lauer P, Brockstedt DG.

Curr Opin Biotechnol. 2012 Dec;23(6):917-23. doi: 10.1016/j.copbio.2012.04.005. Epub 2012 May 18. Review.

PMID:
22608846
10.

Assessment of intratumor non-antibody directed iron oxide nanoparticle hyperthermia cancer therapy and antibody directed IONP uptake in murine and human cells.

Hoopes P, Tate J, Ogden J, Strawbridge R, Fiering S, Petryk A, Cassim S, Giustini A, Demidenko E, Ivkov R, Barry S, Chinn P, Foreman A.

Proc Soc Photo Opt Instrum Eng. 2009 Feb 23;7181:71810P.

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