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Molecular evolution of SARS-CoV-2 from December 2019 to August 2022.
Wolf JM, Wolf LM, Bello GL, Maccari JG, Nasi LA. Wolf JM, et al. J Med Virol. 2023 Jan;95(1):e28366. doi: 10.1002/jmv.28366. J Med Virol. 2023. PMID: 36458547 Free PMC article. Review.
Severe acute respiratorysyndrome coronavirus-2 (SARS-CoV-2) pandemic spread rapidly and this scenario is concerning worldwide, presenting more than 590 million coronavirus disease 2019 cases and 6.4 million deaths. ...Between December 2019 and June 2020, 11 clades were det …
Severe acute respiratorysyndrome coronavirus-2 (SARS-CoV-2) pandemic spread rapidly and this scenario is concerning worldwide, presen …
Prognostic Value of MicroRNA-20b in Acute Myeloid Leukemia.
Cheng Z, Dai Y, Huang W, Zhong Q, Zhu P, Zhang W, Wu Z, Lin Q, Zhu H, Cui L, Qian T, Deng C, Fu L, Liu Y, Zeng T. Cheng Z, et al. Front Oncol. 2021 Feb 18;10:553344. doi: 10.3389/fonc.2020.553344. eCollection 2020. Front Oncol. 2021. PMID: 33680910 Free PMC article.
Acute myeloid leukemia (AML) is a highly heterogeneous disease that requires fine-grained risk stratification for the best prognosis of patients. ...In conclusion, our findings suggest that high miR-20b expression is a poor prognostic indicator for AML, but allo-HSC …
Acute myeloid leukemia (AML) is a highly heterogeneous disease that requires fine-grained risk stratification for the best prognosis …
MiR-20b-5p modulates inflammation, apoptosis and angiogenesis in severe acute pancreatitis through autophagy by targeting AKT3.
Tang GX, Yang MS, Xiang KM, Yang BC, Liu ZL, Zhao SP. Tang GX, et al. Autoimmunity. 2021 Nov;54(7):460-470. doi: 10.1080/08916934.2021.1953484. Epub 2021 Aug 17. Autoimmunity. 2021. PMID: 34402705
BACKGROUND: Severe acute pancreatitis (SAP) is a common acute abdominal disease with high morbidity and mortality. ...Furthermore, miR-20b-5p promoted the angiogenesis of vascular endothelial cells, since the viability, migration and the capability of tube fo …
BACKGROUND: Severe acute pancreatitis (SAP) is a common acute abdominal disease with high morbidity and mortality. ...Furtherm …
Genetic and Epigenetic Regulation of the Innate Immune Response to Gout.
de Lima JD, de Paula AGP, Yuasa BS, de Souza Smanioto CC, da Cruz Silva MC, Dos Santos PI, Prado KB, Winter Boldt AB, Braga TT. de Lima JD, et al. Immunol Invest. 2023 Apr;52(3):364-397. doi: 10.1080/08820139.2023.2168554. Epub 2023 Feb 6. Immunol Invest. 2023. PMID: 36745138 Review.
Genetic variants of inflammasome genes and of genes encoding their molecular partners may influence hyperuricemia and gout susceptibility, while also influencing other comorbidities such as metabolic syndrome and cardiovascular diseases. In this review, we summarize the inflammat …
Genetic variants of inflammasome genes and of genes encoding their molecular partners may influence hyperuricemia and gout susceptibility, w …
miR-20b suppresses mitochondrial dysfunction-mediated apoptosis to alleviate hyperoxia-induced acute lung injury by directly targeting MFN1 and MFN2.
Mu G, Deng Y, Lu Z, Li X, Chen Y. Mu G, et al. Acta Biochim Biophys Sin (Shanghai). 2021 Feb 4;53(2):220-228. doi: 10.1093/abbs/gmaa161. Acta Biochim Biophys Sin (Shanghai). 2021. PMID: 33347533 Free article.
Dysregulation of microRNAs contributes to multiple diseases, including hyperoxia-induced acute lung injury (HALI). In this study, we explored the roles of miR-20b in mediating the response of type II alveolar epithelial cells (ACE IIs) to hyperoxia and the potential …
Dysregulation of microRNAs contributes to multiple diseases, including hyperoxia-induced acute lung injury (HALI). In this study, we …
SARS-CoV-2 Monitoring on Mink Farms in Poland.
Domańska-Blicharz K, Orłowska A, Smreczak M, Munnink BO, Trębas P, Socha W, Niemczuk K, Kawiak-Sadurska M, Opolska J, Lisowska A, Giza A, Bomba A, Iwan E, Koopmans M, Rola J. Domańska-Blicharz K, et al. J Vet Res. 2022 Dec 3;66(4):449-458. doi: 10.2478/jvetres-2022-0066. eCollection 2022 Dec. J Vet Res. 2022. PMID: 36846035 Free PMC article.
INTRODUCTION: Many countries have reported severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infections in mink, and transmission back to humans has raised the concern of novel variants emerging in these animals. ...These genomes belonged to four different varia …
INTRODUCTION: Many countries have reported severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infections in mink, and trans …
Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues.
Eygeris Y, Gupta M, Kim J, Jozic A, Gautam M, Renner J, Nelson D, Bloom E, Tuttle A, Stoddard J, Reynaga R, Neuringer M, Lauer AK, Ryals RC, Sahay G. Eygeris Y, et al. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307813120. doi: 10.1073/pnas.2307813120. Epub 2024 Mar 4. Proc Natl Acad Sci U S A. 2024. PMID: 38437570 Free PMC article.
Using high-throughput formulation and barcoding techniques, we optimized the formulations to select two top lipids-20b and 29d-and investigated their biodistribution in mice. Lipid 20b enabled LNPs to transfect the liver and spleen, and 29d LNP transfected the lung …
Using high-throughput formulation and barcoding techniques, we optimized the formulations to select two top lipids-20b and 29d-and in …
Whole-Genome Sequencing of SARS-CoV-2 Strains from Asymptomatic Individuals in India.
Rangaiah A, Shankar SM, Padukone S, Rangappa KG, Basawarajappa SG. Rangaiah A, et al. Microbiol Resour Announc. 2022 Feb 17;11(2):e0085021. doi: 10.1128/MRA.00850-21. Epub 2022 Jan 27. Microbiol Resour Announc. 2022. PMID: 35084216 Free PMC article.
We performed targeted genome sequencing of 11 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) samples collected from asymptomatic individuals. These nasopharyngeal and oropharyngeal samples were collected during the first wave of coronavirus disease 2019 (COVI …
We performed targeted genome sequencing of 11 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) samples collected from asy …
A Founder Effect Led Early SARS-CoV-2 Transmission in Spain.
Díez-Fuertes F, Iglesias-Caballero M, García-Pérez J, Monzón S, Jiménez P, Varona S, Cuesta I, Zaballos Á, Jiménez M, Checa L, Pozo F, Pérez-Olmeda M, Thomson MM, Alcamí J, Casas I. Díez-Fuertes F, et al. J Virol. 2021 Jan 13;95(3):e01583-20. doi: 10.1128/JVI.01583-20. Print 2021 Jan 13. J Virol. 2021. PMID: 33127745 Free PMC article.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) whole-genome analysis has identified five large clades worldwide which emerged in 2019 (19A and 19B) and in 2020 (20A, 20B, and 20C). ...However, from mid-March to June 2020, G614-bearing viruses (clades 2 …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) whole-genome analysis has identified five large clades worldwide which e …
Genome Sequences of SARS-CoV-2 Strains from the Republic of Moldova.
Ulinici M, Soñora M, Orsini E, Licastro D, Dal Monego S, Todiras M, Lungu L, Groppa S, Marcello A. Ulinici M, et al. Microbiol Resour Announc. 2023 Jan 24;12(1):e0113222. doi: 10.1128/mra.01132-22. Epub 2022 Dec 12. Microbiol Resour Announc. 2023. PMID: 36507680 Free PMC article.
The whole-genome sequences of 15 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains from nasopharyngeal swab samples collected in the Republic of Moldova in June 2020 to September 2021 were determined. Little variability was observed in the early stages, …
The whole-genome sequences of 15 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains from nasopharyngeal swab sample …
62 results